zinterol

{{chembox

| Verifiedfields = changed

| verifiedrevid = 470637341

|ImageFile=Zinterol.svg

|ImageSize=200px

|IUPACName=N-[5-[2-[(1,1-dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide

|OtherNames=

|Section1={{Chembox Identifiers

| IUPHAR_ligand = 3466

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 34825

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 1243407

| InChI = 1/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3

| InChIKey = XJBCFFLVLOPYBV-UHFFFAOYAI

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = XJBCFFLVLOPYBV-UHFFFAOYSA-N

| CASNo_Ref = {{cascite|changed|??}}

| CASNo=37000-20-7

| PubChem=37990

| SMILES = O=S(=O)(Nc1cc(ccc1O)C(O)CNC(C)(C)Cc2ccccc2)C

| MeSHName=Zinterol

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 7167N7AJJR

}}

|Section2={{Chembox Properties

| Formula=C19H26N2O4S

| MolarMass=378.49 g/mol

| Appearance=

| Density=

| MeltingPt=

| BoilingPt=

| Solubility=

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|Section3={{Chembox Hazards

| MainHazards=

| FlashPt=

| AutoignitionPt=

}}

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Zinterol is a beta-adrenergic agonist.{{cite journal |vauthors=Heubach JF, Graf EM, Molenaar P, etal |title=Murine ventricular L-type Ca2+ current is enhanced by zinterol via β1-adrenoceptors, and is reduced in TG4 mice overexpressing the human β2-adrenoceptor |journal=Br. J. Pharmacol. |volume=133 |issue=1 |pages=73–82 |date=May 2001 |pmid=11325796 |pmc=1572761 |doi=10.1038/sj.bjp.0704045}}

Its structure is based on soterenol (antiarrhythmic) and phentermine.

References

{{reflist}}

{{Adrenergic agonists}}

Category:Sulfonamides

Category:Phenols

Category:Phenylethanolamines

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