:1-Deoxy-11beta-hydroxypentalenate dehydrogenase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = 1-deoxy-11beta-hydroxypentalenate dehydrogenase

| EC_number = 1.1.1.340

| CAS_number =

| GO_code =

| image =

| width =

| caption =

}}

1-deoxy-11beta-hydroxypentalenate dehydrogenase ({{EC number|1.1.1.340}}, 1-deoxy-11beta-hydroxypentalenic acid dehydrogenase, {{not a typo|ptlF}} (gene), {{not a typo|penF}} (gene name)) is an enzyme with systematic name 1-deoxy-11beta-hydroxypentalenate:NAD⁺ oxidoreductase.{{cite journal | vauthors = You Z, Omura S, Ikeda H, Cane DE | title = Pentalenolactone biosynthesis: Molecular cloning and assignment of biochemical function to PtlF, a short-chain dehydrogenase from Streptomyces avermitilis, and identification of a new biosynthetic intermediate | journal = Archives of Biochemistry and Biophysics | volume = 459 | issue = 2 | pages = 233–40 | date = March 2007 | pmid = 17178094 | pmc = 1857356 | doi = 10.1016/j.abb.2006.11.016 }} This enzyme catalyses the following chemical reaction

: 1-deoxy-11beta-hydroxypentalenate + NAD⁺ $\backslash rightleftharpoons$ 1-deoxy-11-oxopentalenate + NADH + H⁺

This enzyme from the bacterium Streptomyces avermitilis participates in pentalenolactone biosynthesis.