:Vacuolar interface dermatitis
File:Vacuolar interface dermatitis, annotated.jpg (white arrow) at the dermoepidermal junction.]]
Image:Vacuolar interface dermatitis - high mag.jpg of a vacuolar interface dermatitis with dermal mucin, as may be seen in lupus. H&E stain.]]
Vacuolar interface dermatitis (VAC, also known as liquefaction degeneration, vacuolar alteration or hydropic degeneration) is a dermatitis with vacuolization at the dermoepidermal junction, with lymphocytic inflammation at the epidermis and dermis.{{cite book |author=Bolognia, Jean L.|title=Dermatology |publisher=Mosby |location=St. Louis |year=2007 |pages=11 |isbn=1-4160-2999-0 |display-authors=etal}}
Causes
{{Table of causes of vacuolar interface dermatitis}}
An interface dermatitis with vacuolar alteration, not otherwise specified, may be caused by viral exanthems, phototoxic dermatitis, acute radiation dermatitis, erythema dyschromicum perstans, lupus erythematosus and dermatomyositis.
References
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