1-Fluorohexane
{{Chembox
| Name = 1-Fluorohexane
| ImageFile = 1-Fluorohexane.svg
| ImageFile2 = 1-fluorohexane-3D-balls.png
| ImageCaption =
| IUPACName =
| OtherNames = 1-Hexyl fluoride
| Section1 = {{Chembox Identifiers
| CASNo = 373-14-8
| CASNo_Ref = {{Cascite|correct|CAS}}
| PubChem = 9760
| ChemSpiderID = 9377
| EINECS = 206-763-8
| UNII =
| DTXSID = DTXCID0039308
| StdInChI = 1S/C6H13F/c1-2-3-4-5-6-7/h2-6H2,1H3
| StdInChIKey = OFERIJCSHDJMSA-UHFFFAOYSA-N
| SMILES = CCCCCCF
}}
| Section2 = {{Chembox Properties
|C=6| H=13 | F=1
| Appearance = Liquid
| Density = 0.8 g/cm3
| Solubility =
| MeltingPtC = −103
| BoilingPtC = 92–93
}}
| Section4 = {{Chembox Structure
| CrystalStruct =
}}
| Section7 = {{Chembox Hazards
| MainHazards =
| GHSPictograms = {{GHS02}}{{GHS06}}
| GHSSignalWord = Danger
| HPhrases =
| PPhrases =
}}
| Section6 = {{Chembox Related
| OtherCompounds =
}}
}}
1-Fluorohexane is a chemical compound from the group of aliphatic saturated halogenated hydrocarbons.{{cite web |title=1-Fluorohexane |url=https://spectrabase.com/spectrum/1ycvNGB9JhJ |publisher=spectrabase.com |access-date=6 August 2024}} The chemical formula is {{chem2|CH3(CH2)5F}}.{{cite web |title=1-Fluorohexane {{!}} CAS 373-14-8 {{!}} SCBT - Santa Cruz Biotechnology |url=https://www.scbt.com/p/1-fluorohexane-373-14-8 |publisher=scbt.com |access-date=6 August 2024 |language=en}}{{cite book |last1=Dupasquier |first1=Alfredo |last2=Mills |first2=Allen P. |last3=Brusa |first3=Roberto S. |title=Physics with Many Positrons: Proceedings of the International School of Physics "Enrico Fermi", Course CLXXIV, Varenna on Lake Como, Villa Monastero, 7-17 July 2009 |date=2010 |publisher=IOS Press |isbn=978-1-60750-646-1 |page=391 |url=https://books.google.com/books?id=hjriGqtzNToC&dq=1-fluorohexane&pg=PA391 |access-date=6 August 2024 |language=en}}
Synthesis
1-Fluorohexane can be obtained by reacting 1-chlorohexane or 1-bromohexane with potassium fluoride in ethylene glycol.{{citation| author= | title=Houben-Weyl Methods of Organic Chemistry Vol. V/3, 4th Edition Fluorine and Chlorine Compounds | publisher=Georg Thieme Verlag | isbn=978-3-13-179994-4 | date=2014 | page=153 }}
Physical properties
Chemical properties
The compound reacts with activated Mg:{{cite book |last1=Hagen |first1=A. P. |title=Inorganic Reactions and Methods, The Formation of Bonds to Halogens (Part 2) |date=17 September 2009 |publisher=John Wiley & Sons |isbn=978-0-470-14539-5 |page=77 |url=https://books.google.com/books?id=OcD4P1ZeXdAC&dq=1-fluorohexane&pg=PA77 |access-date=6 August 2024 |language=en}}
::{{chem2|CH3(CH2)5F + Mg (activated) -> C6H13MgF}}
Uses
The compound is primarily used in the field of organic chemistry as a reagent or solvent. Also, 1-fluorohexane is used in physical chemistry as a model compound for understanding the physico-chemical properties of fluorinated hydrocarbons.{{Unreliable source?|date=October 2024}}