Amos Bairoch

{{Short description|Swiss bioinformatician}}

{{redirect|Bairoch|the economic historian|Paul Bairoch}}

{{COI|date=July 2018}}

{{Use dmy dates|date=December 2023}}

{{Infobox scientist

|name = Amos Bairoch

|image = SIB Bairoch.jpg

|image_size = 120px

|caption = Amos Bairoch

|birth_date = {{Birth date and age|1957|11|22|df=yes}}

|birth_place =

|death_date =

|death_place =

|citizenship =

|nationality =

|field = {{Plainlist|

|work_institutions = Swiss Institute of Bioinformatics

|alma_mater = University of Geneva

|doctoral_advisor =

|doctoral_students =

|known_for = {{Plainlist|

| last1 = Bairoch | first1 = A.

| last2 = Boeckmann | first2 = B.

| title = The SWISS-PROT protein sequence data bank

| journal = Nucleic Acids Research

| volume = 19 Suppl

| pages = 2247–2249

| year = 1991

| issue = Suppl

| pmid = 2041811

| pmc = 331359

| doi = 10.1093/nar/19.suppl.2247

}}

| last1 = Gasteiger | first1 = E.

| last2 = Gattiker | first2 = A.

| last3 = Hoogland | first3 = C.

| last4 = Ivanyi | first4 = I.

| last5 = Appel | first5 = R. D.

| last6 = Bairoch | first6 = A.

| title = ExPASy: The proteomics server for in-depth protein knowledge and analysis

| journal = Nucleic Acids Research

| volume = 31

| issue = 13

| pages = 3784–3788

| year = 2003

| pmid = 12824418

| pmc = 168970 | doi=10.1093/nar/gkg563

}}}}

|influences =

|influenced =

|prizes = {{Plainlist|

  • Proteomics pioneer award (2013){{Cite journal | doi = 10.1016/j.euprot.2013.12.002| title = Proteomics Pioneer Award 2013: Professor Amos Bairoch, University of Geneva, Switzerland| journal = EuPA Open Proteomics| volume = 2| pages = 34| year = 2014| last1 = Lisacek | first1 = F. | last2 = Lane | first2 = L. | doi-access = free}}
  • Otto Naegeli prize (2010)
  • European Latsis Prize (2004)}}

| website = {{URL|http://web.expasy.org/groups/people/amos.html}}}}

Amos Bairoch (born 22 November 1957) is a Swiss bioinformatician{{cite web|url=http://web.expasy.org/groups/people/amos.html|archive-url=https://web.archive.org/web/20140214004338/http://web.expasy.org/groups/people/amos.html|title=Amos Bairoch's home page|publisher=ExPASy|archive-date=2014-02-14}}{{Scopus|id=7005698429}}{{EuropePMC|ORCID=0000-0003-2826-6444}} and Professor of Bioinformatics at the Department of Human Protein Sciences of the University of Geneva where he leads the CALIPHO group{{cite web|url=http://www.isb-sib.ch/groups/geneva/calipho-bairoch.html|title=CALIPHO (Computer Analysis and Laboratory Investigation of Proteins of Human Origin) group page on the SIB website|archive-url=https://web.archive.org/web/20130420065450/http://www.isb-sib.ch/groups/geneva/calipho-bairoch.html|archive-date=2013-04-20}} at the Swiss Institute of Bioinformatics (SIB) combining bioinformatics, curation, and experimental efforts to functionally characterize human proteins.{{cite web|url=http://www.genomeweb.com/informatics/sibs-bairoch-step-down-swiss-prot-director-launch-new-human-protein-resource|archive-url=https://web.archive.org/web/20120220003341/http://www.genomeweb.com/informatics/sibs-bairoch-step-down-swiss-prot-director-launch-new-human-protein-resource|archive-date=2012-02-20|publisher=GenomeWeb.com|title=SIB's Bairoch to Step Down as Swiss-Prot Director to Launch New Human Protein Resource}}

His father was the economic historian Paul Bairoch.

Education

His first project as a PhD student was the development of PC/Gene,{{Cite journal

| last1 = Moore | first1 = J.

| last2 = Engelberg | first2 = A.

| last3 = Bairoch | first3 = A.

| title = Using PC/GENE for protein and nucleic acid analysis

| journal = BioTechniques

| volume = 6

| issue = 6

| pages = 566–572

| year = 1988

| pmid = 3273189

}} an MS-DOS–based software package for the analysis of protein and nucleotide sequences. PC/Gene was commercialized, first by a Swiss company (Genofit) then by Intelligenetics in the US which was later bought by Oxford Molecular.{{citation needed|date=April 2015}}

Research

His main work{{GoogleScholar|LJNAj68AAAAJ}} is in the field of protein sequence analysis and more particularly in the development of databases and software tools for this purpose. His most important contribution is the input of human knowledge by careful manual annotation in protein-related data.{{Cite journal

| last1 = Lima | first1 = T.

| last2 = Auchincloss | first2 = A. H.

| last3 = Coudert | first3 = E.

| last4 = Keller | first4 = G.

| last5 = Michoud | first5 = K.

| last6 = Rivoire | first6 = C.

| last7 = Bulliard | first7 = V.

| last8 = De Castro | first8 = E.

| last9 = Lachaize | first9 = C.

| doi = 10.1093/nar/gkn661

| last10 = Baratin | first10 = D.

| last11 = Phan | first11 = I.

| last12 = Bougueleret | first12 = L.

| last13 = Bairoch | first13 = A.

| title = HAMAP: A database of completely sequenced microbial proteome sets and manually curated microbial protein families in UniProtKB/Swiss-Prot

| journal = Nucleic Acids Research

| volume = 37

| issue = Database issue

| pages = D471–D478

| year = 2009

| pmid = 18849571

| pmc =2686602

}}

While working on PC/Gene he started to develop an annotated protein sequence database which became Swiss-Prot and was first released in July 1986.{{Cite journal

| last1 = Bairoch | first1 = A.

| title = Serendipity in bioinformatics, the tribulations of a Swiss bioinformatician through exciting times!

| doi = 10.1093/bioinformatics/16.1.48

| journal = Bioinformatics

| volume = 16

| issue = 1

| pages = 48–64

| year = 2000

| pmid = 10812477

| doi-access = free

}} – a historical account by Bairoch. From 1988 onward it has been a collaborative project with the Data Library group of the European Molecular Biology Laboratory which later evolved into the European Bioinformatics Institute (EBI).

The Swiss-Prot database is the primary protein sequence resource in the world and has been a key research instrument for both bioinformaticians and laboratory-based scientists in a very wide range of applications.{{Cite journal

| last1 = Persson | first1 = B.

| title = Bioinformatics in protein analysis

| journal = EXS

| volume = 88

| pages = 215–231

| year = 2000

| pmid = 10803381

| doi=10.1007/978-3-0348-8458-7_14

| isbn = 978-3-0348-9576-7

}} A measure of its success is the recent development of UniProt, the world's most comprehensive catalogue of information on proteins.{{Cite journal

| last1 = Wu | first1 = C. H.

| last2 = Apweiler | first2 = R.

| last3 = Bairoch | first3 = A.

| last4 = Natale | first4 = D. A.

| last5 = Barker | first5 = W. C.

| last6 = Boeckmann | first6 = B.

| last7 = Ferro | first7 = S.

| last8 = Gasteiger | first8 = E.

| last9 = Huang | first9 = H.

| last10 = Lopez | first10 = R.

| last11 = Magrane | first11 = M.

| last12 = Martin | first12 = M. J.

| last13 = Mazumder | first13 = R.

| last14 = O'Donovan | first14 = C.

| last15 = Redaschi | first15 = N.

| last16 = Suzek | first16 = B.

| title = The Universal Protein Resource (UniProt): An expanding universe of protein information

| doi = 10.1093/nar/gkj161

| journal = Nucleic Acids Research

| volume = 34

| issue = 90001

| pages = D187–D191

| year = 2006

| pmid = 16381842

| pmc =1347523

}} UniProt is a central information resource of protein sequences and functions created by joining the information contained in Swiss-Prot, TrEMBL, and the American Protein Information Resource (PIR) databases.

In 1988, he started to develop PROSITE,{{Cite journal | last1 = Hofmann | first1 = K. | last2 = Bucher | first2 = P. | last3 = Falquet | first3 = L. | last4 = Bairoch | first4 = A. | title = The PROSITE database, its status in 1999 | doi = 10.1093/nar/27.1.215 | journal = Nucleic Acids Research | volume = 27 | issue = 1 | pages = 215–219 | year = 1999 | pmid = 9847184| pmc =148139 }} a database of protein families and domains. A little while later he created ENZYME,{{Cite journal

| pmid = 10592255

| pmc = 102465

| year = 2000

| last1 = Bairoch

| first1 = A

| title = The ENZYME database in 2000

| journal = Nucleic Acids Research

| volume = 28

| issue = 1

| pages = 304–5

| doi=10.1093/nar/28.1.304

}}{{Cite journal

| pmid = 9847212

| pmc = 148167

| year = 1999

| last1 = Bairoch

| first1 = A

| title = The ENZYME data bank in 1999

| journal = Nucleic Acids Research

| volume = 27

| issue = 1

| pages = 310–1

| doi=10.1093/nar/27.1.310

}}{{Cite journal

| pmid = 8594586

| pmc = 145615

| year = 1996

| last1 = Bairoch

| first1 = A

| title = The ENZYME data bank in 1995

| journal = Nucleic Acids Research

| volume = 24

| issue = 1

| pages = 221–2

| doi=10.1093/nar/24.1.221

}}{{Cite journal

| pmid = 7937072

| pmc = 308334

| year = 1994

| last1 = Bairoch

| first1 = A

| title = The ENZYME data bank

| journal = Nucleic Acids Research

| volume = 22

| issue = 17

| pages = 3626–7

| doi=10.1093/nar/22.17.3626

}}{{Cite journal

| pmid = 8332535

| pmc = 309744

| year = 1993

| last1 = Bairoch

| first1 = A

| title = The ENZYME data bank

| journal = Nucleic Acids Research

| volume = 21

| issue = 13

| pages = 3155–6

| doi=10.1093/nar/21.13.3155

}} a nomenclature database on enzymes as well as SeqAnalRef,{{Cite journal

| last1 = Bairoch | first1 = A.

| title = SEQANALREF: A sequence analysis bibliographic reference databank

| journal = Computer Applications in the Biosciences

| volume = 7

| issue = 2

| pages = 268

| year = 1991

| pmid = 2059856

| doi=10.1093/bioinformatics/7.2.268

| url = http://doc.rero.ch/record/300192/files/7-2-268.pdf

}} a sequence analysis bibliographic reference database.{{Cite journal

| last1 = Bairoch | first1 = A.

| title = PROSITE: A dictionary of sites and patterns in proteins

| journal = Nucleic Acids Research

| volume = 19 Suppl

| pages = 2241–2245

| year = 1991

| issue = Suppl

| pmid = 2041810

| pmc = 331358

| doi=10.1093/nar/19.suppl.2241

}}{{Cite journal

| last1 = Hulo | first1 = N.

| last2 = Bairoch | first2 = A.

| last3 = Bulliard | first3 = V.

| last4 = Cerutti | first4 = L.

| last5 = Cuche | first5 = B. A.

| last6 = De Castro | first6 = E.

| last7 = Lachaize | first7 = C.

| last8 = Langendijk-Genevaux | first8 = P. S.

| last9 = Sigrist | first9 = C. J. A.

| doi = 10.1093/nar/gkm977

| title = The 20 years of PROSITE

| journal = Nucleic Acids Research

| volume = 36

| issue = Database issue

| pages = D245–D249

| year = 2007

| pmid = 18003654

| pmc =2238851

}}

In collaboration with Ron Appel he initiated, in August 1993, the first molecular biology WWW server, ExPASy.{{Cite journal

| last1 = Appel | first1 = R. D.

| last2 = Bairoch | first2 = A.

| last3 = Hochstrasser | first3 = D. F.

| title = A new generation of information retrieval tools for biologists: The example of the ExPASy WWW server

| journal = Trends in Biochemical Sciences

| volume = 19

| issue = 6

| pages = 258–260

| year = 1994

| pmid = 8073505

| doi=10.1016/0968-0004(94)90153-8

}} What was intended as a prototype grew rapidly into a major site that provides access to the many databases produced partially or completely in Geneva as well as many tools for the analysis of proteins (proteomics).

In 1998, with colleagues in Geneva and Lausanne, he was one of the founders of the SIB Swiss Institute of Bioinformatics, whose mission is to establish in Switzerland a center of excellence in the field of bioinformatics with an emphasis on research, education, services and the developments of databases and tools.{{Cite journal

| last1 = Hoogland | first1 = C.

| last2 = Mostaguir | first2 = K.

| last3 = Appel | first3 = R.

| last4 = Lisacek | first4 = F.

| title = The World-2DPAGE Constellation to promote and publish gel-based proteomics data through the ExPASy server

| doi = 10.1016/j.jprot.2008.02.005

| journal = Journal of Proteomics

| volume = 71

| issue = 2

| pages = 245–248

| year = 2008

| pmid = 18617148

| doi-access = free

}}

In November 1997, together with Ron Appel and Denis Hochstrasser, he founded GeneBio (Geneva Bioinformatics SA), a company involved in biological knowledge. In April 2000, the above persons with Keith Rose and Robin Offord founded GeneProt (Geneva Proteomics), a high throughput proteomics company that ceased operations in 2005.{{cite web|url=http://www.genomeweb.com/no-new-deals-geneprot-close-its-doors|archive-url=https://web.archive.org/web/20110211051808/http://www.genomeweb.com/no-new-deals-geneprot-close-its-doors|archive-date=2011-02-11|title=With No New Deals, GeneProt to Close Its Doors|date=June 2005 |publisher=GenomeWeb.com}}

Since 2009, in the framework of the CALIPHO group, directed by himself and Lydie Lane, he is involved in the development of neXtProt{{Cite journal

| pmid = 22139911

| pmc = 3245017

| year = 2012

| last1 = Lane

| first1 = L

| title = Ne Xt Prot: A knowledge platform for human proteins

| journal = Nucleic Acids Research

| volume = 40

| issue = Database issue

| pages = D76-83

| last2 = Argoud-Puy

| first2 = G

| last3 = Britan

| first3 = A

| last4 = Cusin

| first4 = I

| last5 = Duek

| first5 = P. D.

| last6 = Evalet

| first6 = O

| last7 = Gateau

| first7 = A

| last8 = Gaudet

| first8 = P

| last9 = Gleizes

| first9 = A

| last10 = Masselot

| first10 = A

| last11 = Zwahlen

| first11 = C

| last12 = Bairoch

| first12 = A

| doi = 10.1093/nar/gkr1179

}}{{Cite journal

| pmid = 25593349

| year = 2015

| last1 = Gaudet

| first1 = P

| title = The neXtProt' knowledgebase on human proteins: Current status

| journal = Nucleic Acids Research

| volume = 43

| issue = Database issue

| pages = D764-70

| last2 = Michel

| first2 = P. A.

| last3 = Zahn-Zabal

| first3 = M

| last4 = Cusin

| first4 = I

| last5 = Duek

| first5 = P. D.

| last6 = Evalet

| first6 = O

| last7 = Gateau

| first7 = A

| last8 = Gleizes

| first8 = A

| last9 = Pereira

| first9 = M

| last10 = Teixeira

| first10 = D

| last11 = Zhang

| first11 = Y

| last12 = Lane

| first12 = L

| last13 = Bairoch

| first13 = A

|author-link13= Amos Bairoch

| doi = 10.1093/nar/gku1178

| pmc=4383972

}}{{Cite journal

| pmid = 23205526

| year = 2013

| last1 = Gaudet

| first1 = P

| title = Ne Xt Prot: Organizing protein knowledge in the context of human proteome projects

| journal = Journal of Proteome Research

| volume = 12

| issue = 1

| pages = 293–8

| last2 = Argoud-Puy

| first2 = G

| last3 = Cusin

| first3 = I

| last4 = Duek

| first4 = P

| last5 = Evalet

| first5 = O

| last6 = Gateau

| first6 = A

| last7 = Gleizes

| first7 = A

| last8 = Pereira

| first8 = M

| last9 = Zahn-Zabal

| first9 = M

| last10 = Zwahlen

| first10 = C

| last11 = Bairoch

| first11 = A

| last12 = Lane

| first12 = L

| doi = 10.1021/pr300830v

}} a resource which aims to provide life scientists with a broad spectrum of knowledge on all human proteins.

He is also involved in the development of the Cellosaurus a knowledge resource on cell lines.

According to Google Scholar and Scopus, {{as of|2015}} his most highly cited peer reviewed papers in scientific journals have been published in Nucleic Acids Research,{{Cite journal

| last1 = Bairoch | first1 = A.

| last2 = Apweiler | first2 = R.

| last3 = Wu | first3 = C. H.

| last4 = Barker | first4 = W. C.

| last5 = Boeckmann | first5 = B.

| last6 = Ferro | first6 = S.

| last7 = Gasteiger | first7 = E.

| last8 = Huang | first8 = H.

| last9 = Lopez | first9 = R.

| last10 = Magrane | first10 = M.

| last11 = Martin | first11 = M. J.

| last12 = Natale | first12 = D. A.

| last13 = O'Donovan | first13 = C.

| last14 = Redaschi | first14 = N.

| last15 = Yeh | first15 = L. S.

| title = The Universal Protein Resource (UniProt)

| doi = 10.1093/nar/gki070

| journal = Nucleic Acids Research

| volume = 33

| issue = Database issue

| pages = D154–D159

| year = 2004

| pmid = 15608167

| pmc =540024

}}{{Cite journal

| last1 = Boeckmann | first1 = B.

| last2 = Bairoch | first2 = A.

| last3 = Apweiler | first3 = R.

| last4 = Blatter | first4 = M. C.

| last5 = Estreicher | first5 = A.

| last6 = Gasteiger | first6 = E.

| last7 = Martin | first7 = M. J.

| last8 = Michoud | first8 = K.

| last9 = O'Donovan | first9 = C.

| last10 = Phan | first10 = I.

| last11 = Pilbout | first11 = S.

| last12 = Schneider | first12 = M.

| title = The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003

| doi = 10.1093/nar/gkg095

| journal = Nucleic Acids Research

| volume = 31

| issue = 1

| pages = 365–370

| year = 2003

| pmid = 12520024

| pmc =165542

}}{{Cite journal

| last1 = Apweiler | first1 = R.

|author-link1= Rolf Apweiler

| last2 = Attwood | first2 = T. K.

|author-link2= Terri Attwood

| last3 = Bairoch | first3 = A.

|author-link3= Amos Bairoch

| last4 = Bateman | first4 = A.

|author-link4= Alex Bateman

| last5 = Birney | first5 = E.

|author-link5= Ewan Birney

| last6 = Biswas | first6 = M.

| last7 = Bucher | first7 = P.

| last8 = Cerutti | first8 = L.

| last9 = Corpet | first9 = F.

| last10 = Croning | first10 = M. D.

| last11 = Durbin | first11 = R.

| last12 = Falquet | first12 = L.

| last13 = Fleischmann | first13 = W.

| last14 = Gouzy | first14 = J.

| last15 = Hermjakob | first15 = H.

| last16 = Hulo | first16 = N.

| last17 = Jonassen | first17 = I.

| last18 = Kahn | first18 = D.

| last19 = Kanapin | first19 = A.

| last20 = Karavidopoulou | first20 = Y.

| last21 = Lopez | first21 = R.

| last22 = Marx | first22 = B.

| last23 = Mulder | first23 = N. J.

| last24 = Oinn | first24 = T. M.

| last25 = Pagni | first25 = M.

| last26 = Servant | first26 = F.

| last27 = Sigrist | first27 = C. J.

| last28 = Zdobnov | first28 = E. M.

| title = The InterPro database, an integrated documentation resource for protein families, domains and functional sites

| journal = Nucleic Acids Research

| volume = 29

| issue = 1

| pages = 37–40

| year = 2001

| pmid = 11125043

| pmc = 29841 | doi=10.1093/nar/29.1.37

}}{{Cite journal

| pmid = 12520011

| pmc = 165493

| year = 2003

| last1 = Mulder

| first1 = N. J.

| title = The InterPro Database, 2003 brings increased coverage and new features

| journal = Nucleic Acids Research

| volume = 31

| issue = 1

| pages = 315–8

| last2 = Apweiler

| first2 = R

|author-link2= Rolf Apweiler

| last3 = Attwood

| first3 = T. K.

|author-link3= Terri Attwood

| last4 = Bairoch

| first4 = A

|author-link4= Amos Bairoch

| last5 = Barrell

| first5 = D

| last6 = Bateman

| first6 = A

|author-link6= Alex Bateman

| last7 = Binns

| first7 = D

| last8 = Biswas

| first8 = M

| last9 = Bradley

| first9 = P

| last10 = Bork

| first10 = P

|author-link10= Peer Bork

| last11 = Bucher

| first11 = P

| last12 = Copley

| first12 = R. R.

| last13 = Courcelle

| first13 = E

| last14 = Das

| first14 = U

| last15 = Durbin

| first15 = R

|author-link15= Richard M. Durbin

| last16 = Falquet

| first16 = L

| last17 = Fleischmann

| first17 = W

| last18 = Griffiths-Jones

| first18 = S

| last19 = Haft

| first19 = D

| last20 = Harte

| first20 = N

| last21 = Hulo

| first21 = N

| last22 = Kahn

| first22 = D

| last23 = Kanapin

| first23 = A

| last24 = Krestyaninova

| first24 = M

| last25 = Lopez

| first25 = R

| last26 = Letunic

| first26 = I

| last27 = Lonsdale

| first27 = D

| last28 = Silventoinen

| first28 = V.

| last29 = Orchard

| first29 = S. E.

| last30 = Pagni

| first30 = M.

| last31 = Pagni

| first31 = Marco

| last32 = Peyruc

| first32 = D.

| last33 = Ponting

| first33 = C.P.

|author-link33=Chris Ponting

| last34 = Selengut

| first34 = J.D.

| last35 = Servant

| first35 = F.

| last36 = Sigrist

| first36 = C.J.A.

| last37 = Vaughan

| first37 = R.

| last38 = Zdobnov

| first38 = E.M.

| doi=10.1093/nar/gkg046

}}{{Cite journal

| pmid = 15608177

| pmc = 540060

| year = 2005

| last1 = Mulder

| first1 = N. J.

| title = InterPro, progress and status in 2005

| journal = Nucleic Acids Research

| volume = 33

| issue = Database issue

| pages = D201-5

| last2 = Apweiler | first2 = R |author-link2= Rolf Apweiler

| last3 = Attwood | first3 = T. K. |author-link3= Terri Attwood

| last4 = Bairoch | first4 = A |author-link4= Amos Bairoch

| last5 = Bateman | first5 = A |author-link5= Alex Bateman

| last6 = Binns

| first6 = D

| last7 = Bradley

| first7 = P

| last8 = Bork | first8 = P |author-link8= Peer Bork

| last9 = Bucher

| first9 = P

| last10 = Cerutti

| first10 = L

| last11 = Copley

| first11 = R

| last12 = Courcelle

| first12 = E

| last13 = Das

| first13 = U

| last14 = Durbin | first14 = R |author-link14= Richard M. Durbin

| last15 = Fleischmann

| first15 = W

| last16 = Gough | first16 = J |author-link16= Julian Gough (scientist)

| last17 = Haft

| first17 = D

| last18 = Harte

| first18 = N

| last19 = Hulo

| first19 = N

| last20 = Kahn

| first20 = D

| last21 = Kanapin

| first21 = A

| last22 = Krestyaninova

| first22 = M

| last23 = Lonsdale

| first23 = D

| last24 = Lopez

| first24 = R

| last25 = Letunic

| first25 = I

| last26 = Madera

| first26 = M

| last27 = Maslen

| first27 = J

| last28 = McDowall

| first28 = J

| last29 = Mitchell

| first29 = A

| last30 = Nikolskaya

| first30 = A. N.

| display-authors = 29

| doi = 10.1093/nar/gki106

}} {{open access}} the Biochemical Journal,{{Cite journal

| pmid = 8687420

| pmc = 1217404

| year = 1996

| last1 = Henrissat

| first1 = B

| title = Updating the sequence-based classification of glycosyl hydrolases

| journal = The Biochemical Journal

| volume = 316

| pages = 695–6

| last2 = Bairoch

| first2 = A

| issue=2

| doi=10.1042/bj3160695

}}{{Cite journal

| pmid = 8352747

| pmc = 1134435

| year = 1993

| last1 = Henrissat

| first1 = B

| title = New families in the classification of glycosyl hydrolases based on amino acid sequence similarities

| journal = The Biochemical Journal

| volume = 293

| pages = 781–8

| last2 = Bairoch

| first2 = A

| issue=3

| doi=10.1042/bj2930781

}} Nature,{{Cite journal | doi = 10.1038/387394a0| pmid = 9163424| title = Molecular basis of symbiosis between Rhizobium and legumes| journal = Nature| volume = 387| issue = 6631| pages = 394–401| year = 1997| last1 = Freiberg | first1 = C. | last2 = Fellay | first2 = R. M. | last3 = Bairoch | first3 = A. | last4 = Broughton | first4 = W. J. | last5 = Rosenthal | first5 = A. | last6 = Perret | first6 = X. | bibcode = 1997Natur.387..394F| s2cid = 4336941}} Briefings in Bioinformatics,{{Cite journal

| pmid = 12230035

| year = 2002

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| first1 = C. J.

| title = PROSITE: A documented database using patterns and profiles as motif descriptors

| journal = Briefings in Bioinformatics

| volume = 3

| issue = 3

| pages = 265–74

| last2 = Cerutti

| first2 = L

| last3 = Hulo

| first3 = N

| last4 = Gattiker

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| last6 = Pagni

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| url = https://archive-ouverte.unige.ch/unige:40347/ATTACHMENT01

| doi-access = free

}} and Database.{{Cite journal

| last1 = Gaudet | first1 = P.

| last2 = Bairoch | first2 = A. |author-link2= Amos Bairoch

| last3 = Field | first3 = D.

| last4 = Sansone | first4 = S. -A.

| last5 = Taylor | first5 = C.

| last6 = Attwood | first6 = T. K. |author-link6= Terri Attwood

| last7 = Bateman | first7 = A. |author-link7= Alex Bateman

| last8 = Blake | first8 = J. A.

| last9 = Built | first9 = C. J.

| last10 = Cherry | first10 = J. M.

| last11 = Chisholm | first11 = R. L.

| last12 = Cochrane | first12 = G.

| last13 = Cook | first13 = C. E.

| last14 = Eppig | first14 = J. T.

| last15 = Galperin | first15 = M. Y.

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| last17 = Goble | first17 = C. A. |author-link17= Carole Goble

| last18 = Gojobori | first18 = T. |author-link18= Takashi Gojobori

| last19 = Hancock | first19 = J. M.

| last20 = Howe | first20 = D. G.

| last21 = Imanishi | first21 = T.

| last22 = Kelso | first22 = J.

| last23 = Landsman | first23 = D.

| last24 = Lewis | first24 = S. E. |author-link24= Suzanna Lewis

| last25 = Karsch Mizrachi | first25 = I.

| last26 = Orchard | first26 = S.

| last27 = Ouellette | first27 = B. F. F.

| last28 = Ranganathan | first28 = S.

| last29 = Richardson | first29 = L.

| last30 = Rocca-Serra | first30 = P.

| title = Towards BioDBcore: A community-defined information specification for biological databases

| doi = 10.1093/database/baq027

| journal = Database

| volume = 2011

| pages = baq027

| year = 2011

| pmid = 21205783

| pmc =3017395

}}

Awards and honours

Bairoch was the recipient of the 1993 Friedrich Miescher Award from the Swiss Society of Biochemistry, the 1995 Helmut Horten Foundation Incentive Award, the 2004 Pehr Edman award, the 2004 European Latsis Prize, the 2010 Otto Naegeli

prize, the 2011 HUPO Distinguished Achievement Award in Proteomic Sciences.,{{cite web|url=http://www.hupo.org/communications/HUPO_awards/|archive-url=https://web.archive.org/web/20130605151023/http://www.hupo.org/communications/HUPO_awards/|archive-date=2013-06-05|publisher=HUPO|title=HUPO Distinguished Awards}} the 2013 EUPA proteomics pioneer award, and in 2018 the ABRF Award.

Quotes

{{Cquote|As the process keeps going down we're reaching the point where every genome that can be sequenced will be sequenced.{{Cite journal

| pages = 22–5

| year = 2008

| pmid = 18769412

| doi = 10.1038/455022a

| issue = 7209

| volume = 455

| title = Big data: Wikiomics

| journal = Nature

| last1 = Waldrop | first1 = M.

| doi-access = free

}}}}

References