Arun Kumar Shukla
{{Short description|Indian structural biologist}}
{{Use dmy dates|date=March 2019}}
{{Use Indian English|date=March 2019}}
{{Infobox scientist
| name = Arun Kumar Shukla
| image =
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| birth_date =
| birth_place = Kushinagar, Uttar Pradesh, India
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| nationality = Indian
| fields = {{ublist | Structural biology }}
| workplaces = {{ublist | Duke University | Indian Institute of Technology, Kanpur }}
| alma_mater = {{ublist|Jawaharlal Nehru University | Max Planck Institute|Duke University | Stanford University }}
| doctoral_advisor = {{ublist|Hartmut Michel | Robert J. Lefkowitz | Brian Kobilka}}
| doctoral_students =
| known_for = Studies on G protein-coupled receptor
| awards = {{ublist| 2023 Infosys Prize in Life Sciences |2022 Fellow, Indian National Science Academy|2021 Shanti Swarup Bhatnagar Prize for Science and Technology| 2019 Rajib Goyal Prize by Kurukshetra University| 2017 B. M. Birla Science Prize | 2016 NASI-Young Scientist Platinum Jubilee Award | 2017 EMBO Young Investigator Award | 2017/18 N-BIOS Prize | 2018 ICMR Shakuntala Amir Chand Prize | 2018 CDRI Award}}
}}
Arun Kumar Shukla is an Indian structural biologist and the Joy-Gill Chair professor at the department of biological sciences and bioengineering at the Indian Institute of Technology, Kanpur.{{Cite web |url=https://www.iitk.ac.in/bsbe/arun-k-shukla |title=Arun K. Shukla IITK |date=2018-12-30 |website=www.iitk.ac.in |access-date=2018-12-30}} Known for his studies on G protein-coupled receptor, Shukla is a Wellcome Trust-DBT Intermediate Fellow and a recipient of the SwarnaJayanti Fellowship of the Department of Science and Technology.{{Cite web |url=http://www.dst.gov.in/sites/default/files/Final-List-SwarnaJayanti-Fellows-2017-18.pdf |title=List of Awardees - SwarnaJayanti Fellowships Scheme – 2017-18 |date=2018-12-30 |website=Department of Science and Technology |access-date=2018-12-30}} The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2017/18. He received the 2021 Shanti Swarup Bhatnagar Prize for Science and Technology in Biological Science.{{cite web |title=Shanti Swarup Bhatnagar Prize (SSB) for Science and Technology 2021 |url=https://ssbprize.gov.in/WriteReadData/LatestUpdates/202109260133259214500SSBPrize2021Website.pdf |website=sbprize.gov.in |publisher=Council of Scientific and Industrial Research |access-date=26 September 2021}} He was awarded the [https://www.infosysprize.org/laureates/2023/arun-shulka.html Infosys Prize 2023] in Life Sciences his outstanding contributions to the biology of G-protein coupled receptors (GPCRs).
Biography
File:A building at IIT Kanpur.jpg
Dr. Arun Kumar Shukla was born on 01 November 1981{{cite web |title=Arun Kumar Shukla Biography |url=https://nikhilbharat.com/arun-kumar-shukla-biography-in-hindi/ |website=Online Hindi world |date=27 November 2021}} in Kushinagar in the Indian state of Uttar Pradesh,{{Cite web |url=https://www.telegraphindia.com/science-tech/better-pill/cid/1377263 |title=Better pill |date=2018-12-30 |website=www.telegraphindia.com |language=en |access-date=2018-12-30}} earned his master's degree in biotechnology from Jawaharlal Nehru University after which he did his doctoral studies under the guidance of Hartmut Michel (Nobel Laureate, 1988) of Max Planck Institute of Biophysics. His post-doctoral work was with Robert J. Lefkowitz (Nobel Laureate, 2012) of Duke University and Brian Kobilka (Nobel Laureate, 2012) of Stanford University and he started his career at Duke University as an assistant professor at their department of medicine. Returning to India, he joined the Indian Institute of Technology, Kanpur (IITK) at the Department of Biological Sciences and Bioengineering (BSBE){{Cite web |url=https://www.iitk.ac.in/bsbe/people |title=BSBE People |date=2018-12-30 |website=www.iitk.ac.in |access-date=2018-12-30}} where he holds the position of a professor{{Cite web |url=https://samviti.com/profile/arun-shukla-NzA4 |title=Arun Shukla on Samviti |date=2018-12-30 |website=samviti.com |language=en |access-date=2018-12-30}} and heads the Laboratory of GPCR Biology.{{Cite web |url=https://sites.google.com/site/laboratoryofgpcrbiology/curriculum-vitae |title=Principal Investigator - Laboratory of GPCR Biology |date=2018-12-30 |website=sites.google.com |access-date=2018-12-30}}
Shukla is known to have carried out extensive research on G protein-coupled receptor and his research is reported to have led to easier regulation of these receptors for better drug efficacy.{{Cite news |url=https://www.thehindu.com/sci-tech/Drug-discovery-for-GPCR-signalling-made-easy-by-IIT-Kanpur/article16973255.ece |title=Drug discovery for GPCR signalling made easy by IIT Kanpur |last=Prasad |first=R. |date=2017-01-01 |newspaper=The Hindu |language=en-IN |access-date=2018-12-30}} He led a team of IITK scientists who developed nanomachines which could be designed to selectively target signalling events inside living cells.{{Cite web |url=https://www.thehindubusinessline.com/news/science/iitkanpur-scientistled-team-designs-nanomachines-that-can-correct-anomalies-inside-living-cells/article9885557.ece |title=IIT-Kanpur scientist-led team designs nano-machines that can correct anomalies inside living cells |last=Jayan |first=T. V. |date=8 January 2018 |website=@businessline |language=en |access-date=2018-12-30}} The technique developed by them is in use with several drugs that are available in the market such as Telmisartan, Olmesartan, Fexofenadine, Propranolol, and Metoprolol. He has published a number of articles and has contributed chapters to books published by others;{{Cite web |url=https://sites.google.com/site/laboratoryofgpcrbiology/publica |title=Research Publications - Laboratory of GPCR Biology |date=2018-12-31 |website=sites.google.com |access-date=2018-12-31}}{{Refn|group=note|Please see Selected bibliography section}} Google Scholar, an online repository of scientific articles has listed 75 of them.{{Cite web |url=https://scholar.google.co.in/citations?user=xIgDSCwAAAAJ&hl=en |title=Arun K. Shukla - Google Scholar Citations |date=2018-12-31 |website=scholar.google.co.in |access-date=2018-12-31}}
Awards and honours
Shukla received the Infosys Prize 2023 in Life Sciences, he was selected for this prestigious award by an eminent jury chaired by MIT Professor, [https://www.infosysprize.org/jury/life-sciences.html Mriganka Sur]. He received the 2021 Shanti Swarup Bhatnagar Prize for Science and Technology in Biological Science. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2017/18.{{Cite web |url=http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf |title=Awardees of National Bioscience Awards for Career Development |date=2016 |publisher=Department of Biotechnology |access-date=2017-11-20 |archive-date=4 March 2018 |archive-url=https://web.archive.org/web/20180304191331/http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf |url-status=dead }} He has also received the B. M. Birla Science Prize (2017),{{Cite web |url=https://www.thehansindia.com/posts/index/Telangana/2018-01-29/BM-Birla-Science-Prize-presented/354957 |title=BM Birla Science Prize presented |date=2018-12-31 |website=www.thehansindia.com |access-date=2018-12-31}} NASI-Young Scientist Platinum Jubilee Award of the National Academy of Sciences, India (2016),{{Cite web |url=http://www.nasi.org.in/yspja.htm |title=The National Academy of Sciences, India - Activities |date=2018-12-31 |website=www.nasi.org.in |access-date=2018-12-31 |archive-date=9 January 2019 |archive-url=https://web.archive.org/web/20190109212436/http://www.nasi.org.in/yspja.htm |url-status=dead }} CDRI Award (2018),{{Cite web |url=http://www.cdri.res.in/pdf/CDRIAwardsNotification.pdf |title=List of previous CDRI Awardees |date=2018-12-31 |website=Central Drug Research Institute |access-date=2018-12-31 |archive-url=https://web.archive.org/web/20181231194121/http://www.cdri.res.in/pdf/CDRIAwardsNotification.pdf |archive-date=31 December 2018 |url-status=dead }} Shakuntala Amir Chand Prize of the Indian Council for Medical Research (2018){{Cite web |url=https://www.icmr.gov.in/awards |title=Awards - Indian Council of Medical Research |date=2018-12-31 |website=ICMR |access-date=2018-12-31 |archive-url=https://web.archive.org/web/20181231194130/https://www.icmr.gov.in/awards |archive-date=31 December 2018 |url-status=dead }}{{Cite web |url=https://www.iitk.ac.in/dofa/news-archive |title=News Archive |last=Vishwas |date=2018-12-31 |website=www.iitk.ac.in |language=en-gb |access-date=2018-12-31}} and the EMBO Young Investigator Award (2017).{{Cite web |url=https://www.pinterest.com/pin/155514993366608507/ |title=IITK faculty Dr. Arun Shukla, Department of Biosciences & bioengineering has been selected as the EMBO Young Investigator |date=2018-12-30 |website=Pinterest |language=en |access-date=2018-12-30}} He was elected as a fellow of the Indian National Science Academy in 2022.{{Cite web |title=INSA :: Indian Fellows Elected |url=https://www.insaindia.res.in/ref3.php |access-date=2022-10-22 |website=www.insaindia.res.in}} In 2022 and 2024, Shukla was a laureate of the Asian Scientist 100 by the Asian Scientist.
Selected bibliography
- {{Cite journal |last1=Ghosh |first1=Eshan |last2=Nidhi |first2=Kumari |last3=Shukla |first3=Arun K. |date=2014 |title=SnapShot: GPCR-Ligand Interactions |journal=Cell |volume=159 |issue=7 |pages=1712–1712.e1 |doi=10.1016/j.cell.2014.12.008 |pmid=25525884 |issn=0092-8674|doi-access=free }}
- {{Cite journal |last1=Reiter |first1=Eric |last2=Ahn |first2=Seungkirl |last3=Shukla |first3=Arun K. |last4=Lefkowitz |first4=Robert J. |date=2012-01-11 |title=Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors |journal=Annual Review of Pharmacology and Toxicology |volume=52 |issue=1 |pages=179–197 |doi=10.1146/annurev.pharmtox.010909.105800 |issn=0362-1642 |pmc=3628752 |pmid=21942629}}
- {{Cite journal |last1=Lefkowitz |first1=Robert J. |last2=Yates |first2=John R. |last3=Shenoy |first3=Sudha K. |last4=Chen |first4=Minyong |last5=Zhao |first5=Yang |last6=Shukla |first6=Arun K. |last7=McClatchy |first7=Daniel B. |last8=Xiao |first8=Kunhong |date=2007-07-17 |title=Functional specialization of β-arrestin interactions revealed by proteomic analysis |journal=Proceedings of the National Academy of Sciences |language=en |volume=104 |issue=29 |pages=12011–12016 |doi=10.1073/pnas.0704849104 |issn=1091-6490 |pmc=1913545 |pmid=17620599 |bibcode=2007PNAS..10412011X |doi-access=free }}
- {{Cite journal |last1=Lefkowitz |first1=Robert J. |last2=Whalen |first2=Erin J. |last3=Muehlbauer |first3=Michael J. |last4=Chen |first4=J. Ruthie |last5=Lam |first5=Christopher M. |last6=DeWire |first6=Scott M. |last7=Violin |first7=Jonathan D. |last8=Kovacs |first8=Jeffrey J. |last9=Shukla |first9=Arun K. |date=2009-05-01 |title=β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice |journal=The Journal of Clinical Investigation |language=en |volume=119 |issue=5 |pages=1312–1321 |doi=10.1172/JCI36806 |issn=0021-9738 |pmc=2673863 |pmid=19349687}}
- {{Cite journal |last1=Lefkowitz |first1=Robert J. |last2=Gygi |first2=Steven P. |last3=Ma'ayan |first3=Avi |last4=Mizuno |first4=Kensaku |last5=Cheng |first5=Yishan |last6=Lin |first6=Yuan |last7=Zhao |first7=Shan |last8=Lachmann |first8=Alexander |last9=Hernandez |first9=Marylens |date=2010-08-24 |title=Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR) |journal=Proceedings of the National Academy of Sciences |language=en |volume=107 |issue=34 |pages=15299–15304 |doi=10.1073/pnas.1008461107 |issn=1091-6490 |pmc=2930550 |pmid=20686112 |bibcode=2010PNAS..10715299X |doi-access=free }}
See also
{{portal|India||Biology}}
Notes
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References
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Further reading
- {{Cite journal |last=The |first=Company of Biologists |date=2017-02-15 |title=Cell scientist to watch – Arun Shukla |journal=J Cell Sci |language=en |volume=130 |issue=4 |pages=659–661 |doi=10.1242/jcs.201384 |issn=1477-9137 |doi-access=free }}
- {{Cite journal |last=Gewin |first=Virginia |date=2015-04-15 |title=Turning point: Arun Shukla |journal=Nature |language=en |volume=520 |issue=7547 |pages=397 |doi=10.1038/nj7547-397a |issn=0028-0836|doi-access=free }}
External links
- {{Cite web |url=https://www.youtube.com/watch?v=2tJIEBO25AQ |title=Prof. Arun K Shukla @Department of Biological Sciences and Bioengineering |last=IIT KANPUR |website=YouTube |date=16 August 2017 |access-date=2018-12-30}}
{{N-BIOS Laureates 2010–2019}}
{{SSBPST recipients in Biological Science}}
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Category:Year of birth missing (living people)
Category:N-BIOS Prize recipients
Category:Jawaharlal Nehru University alumni
Category:Max Planck Society alumni
Category:Duke University alumni
Category:Duke University School of Medicine faculty
Category:Stanford University alumni