Balasubramanian Gopal

{{Short description|Indian biologist (born 1970)}}

{{Use dmy dates|date=January 2019}}

{{Use Indian English|date=January 2019}}

{{Infobox scientist

| name = Balasubramanian Gopal

| image =

| alt =

| caption =

| birth_date = {{Birth date and age|df=yes|1970|8|31}}

| birth_place = India

| death_date =

| death_place =

| fields = {{ublist | Molecular biophysics | Structural biology }}

| workplaces = {{ublist | Indian Institute of Science | Torrent Pharmaceuticals }}

| alma_mater = {{ublist | Indian Institute of Technology, Kanpur | Indian Institute of Science | National Institute for Medical Research }}

| doctoral_advisor =

| doctoral_students =

| known_for = Studies on molecular biophysics

| awards = {{ublist | 2010 National Bioscience Award for Career Development | 2015 Shanti Swarup Bhatnagar Prize }}

}}

Balasubramanian Gopal (born 1970) is an Indian structural biologist, molecular biophysicist and a professor at the Molecular Biophysics Unit of the Indian Institute of Science.{{cite news | url=http://www.thehindu.com/news/national/11-selected-for-shanti-swarup-bhatnagar-award/article7692862.ece | title=11 selected for Shanti Swarup Bhatnagar award | newspaper=The Hindu | date=27 September 2015 | access-date=3 November 2016}}{{cite web | url=http://ssbprize.gov.in/content/Detail.aspx?AID=139 | title=Brief Profile of the Awardee | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | access-date=5 October 2016}} He is known for his studies on cell wall synthesis in Staphylococcus aureus and is an elected fellow of the National Academy of Sciences, India,{{cite web|url=http://www.nasi.org.in/fellows.asp?RsFilter=G |title=NASI fellows |publisher=National Academy of Sciences, India |date=2016 |access-date=4 November 2016 |url-status=dead |archive-url=https://web.archive.org/web/20141021102942/http://www.nasi.org.in/fellows.asp?RsFilter=G |archive-date=21 October 2014 }} Indian National Science Academy{{cite web | url=http://insaindia.res.in/detail.php?id=P16-1717 | title=Indian fellow | publisher=Indian National Science Academy | date=2016 | access-date=2 November 2016 | archive-date=4 November 2016 | archive-url=https://web.archive.org/web/20161104005727/http://insaindia.res.in/detail.php?id=P16-1717 | url-status=dead }} and the Indian Academy of Sciences.{{cite web | url=http://www.ias.ac.in/describe/fellow/Gopal,_Prof._Balasubramanian | title=Fellow Profile | publisher=Indian Academy of Sciences | date=2016 | access-date=2 November 2016}} He received the National Bioscience Award for Career Development of the Department of Biotechnology in 2010.{{cite web | url=http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf | title=Awardees of National Bioscience Awards for Career Development | publisher=Department of Biotechnology | date=2016 | access-date=17 October 2016 | archive-date=4 March 2018 | archive-url=https://web.archive.org/web/20180304191331/http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf | url-status=dead }} The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2015, for his contributions to biological sciences.{{cite web | url=http://ssbprize.gov.in/Content/AwardeeList.aspx | title=View Bhatnagar Awardees | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | access-date=5 October 2016}}

Biography

Balasubramnian Gopal, born on 31 August 1970, completed his master's degree at Indian Institute of Technology, Kanpur and started his career as a biochemist by joining Torrent Pharmaceuticals at their Ahmedabad station.{{cite journal | title=Biotech in Bangalore | author=Gene Russo | journal=Nature | date=April 2008 | volume=452 |issue = 7187| pages=660–61 | doi=10.1038/nj7187-660a| pmid=18389533 }} Later, he took a break from his job and joined the Indian Institute of Science (IISc) from where he secured a PhD. Moving to the UK, he did his post-doctoral studies in crystallography at the National Institute for Medical Research. Returning to India, he joined the Molecular Biophysics Unit of IISc as a member of Lab 301{{cite web | url=http://mbu.iisc.ac.in/~bggrp/index_files/Page1207.htm | title=Members | publisher=MBU - Indian Institute of Science | date=2016 | access-date=3 November 2016}} where he and his colleagues are engaged in researches on structural and mechanistic aspects of membrane-associated proteins involved in inter-cell communication, transcriptional regulation and mediate antimicrobial resistance.{{cite web | url=http://mbu.iisc.ac.in/~bggrp/ | title=Lab 301 | publisher=MBU - Indian Institute of Science | date=2016 | access-date=3 November 2016}}

Gopal is known to have done considerable research in molecular biophysics{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | access-date=5 October 2016 | pages=34 | archive-url=https://web.archive.org/web/20160304043957/http://www.csirhrdg.res.in/ssb.pdf | archive-date=4 March 2016 | url-status=dead }} and has contributed to widening our understanding of the cell wall synthesis in Staphylococcus aureus, a common gram-positive bacterium found in human respiratory tract and skin.{{cite web | url=http://www.rcb.res.in/upload/2014/Dr.Gopal_Aug4th_seminar_LCDTV.pdf | title=Seminar series | publisher=Regional Centre for Biotechnology | date=2016 | access-date=3 November 2016}} He has published his research findings as articles in peer-reviewed journals{{Refn|group=note|Please see Selected bibliography section}} and Google Scholar, an online article repository has listed 77 of them.{{cite web | url=https://scholar.google.co.in/citations?user=EsBdbbkAAAAJ | title=Gopal on Google Scholar | publisher=Google Scholar | date=2016 | access-date=3 November 2016}} He has delivered keynote addresses at several seminars including the Graduate Students' Meet 2007{{cite web | url=http://graduatestudentsmeet.weebly.com/-hall-of-fame.html | title=Graduate Students' Meet 2007 | publisher=Graduate Students' Meet | date=2016 | access-date=3 November 2016}} and the 2nd International Conference on Structural and Functional Genomics organised by Sastra university, Tanjore in August 2016.{{cite web | url=http://sastra.edu/icsafg2016/sp.html | title=International Conference on Structural and Functional Genomics | publisher=Sastra University | date=2016 | access-date=3 November 2016}}

Awards and honors

The Department of Biotechnology awarded him the National Bioscience Award for Career Development in 2010. The Indian Academy of Sciences elected him as its fellow in 2013, the same year as he was elected as a fellow by the National Academy of Sciences, India. He was awarded the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, by the Council of Scientific and Industrial Research in 2015.{{cite web | url=http://alumni.iisc.ernet.in/news/10648 | title=Prof. Balasubramanian Gopal wins coveted Shanti Swarup Bhatnagar Award 2015 | publisher=IISc Alumni Association | date=30 September 2015 | access-date=3 November 2016}} The elected fellowship of the Indian National Science Academy reached him in 2016.

Selected bibliography

  • {{cite journal | title=Structural and biochemical bases for the redox sensitivity of Mycobacterium tuberculosis RslA |author1=Krishan Gopal Thakur |author2=T Praveena |author3=B Gopal | journal=Journal of Molecular Biology | date=April 2010 | volume=397 | issue=5 | pages=1199–1208 | doi=10.1016/j.jmb.2010.02.026 | pmid=20184899 | pmc=2877774}}
  • {{cite journal | title=Molecular basis for the role of Staphylococcus aureus penicillin binding protein 4 in antimicrobial resistance |author1=Vikas Navratna |author2=Savitha Nadig |author3=Varun Sood |author4=K Prasad |author5=Gayathri Arakere |author6=B Gopal | journal=Journal of Bacteriology | date=January 2010 | volume=192 | issue=1 | pages=134–144 | doi=10.1128/JB.00822-09 | pmid=19854906 | pmc=2798245}}
  • {{cite journal | title=Structure-based phylogeny as a diagnostic for functional characterization of proteins with a cupin fold |author1=Garima Agarwal |author2=Malligarjunan Rajavel |author3=Balasubramanian Gopal |author4=Narayanaswamy Srinivasan | journal=PLOS ONE | date=May 2009 | volume=4 | issue=5 | doi=10.1371/journal.pone.0005736 |pmid=19478949 |pmc=2684688 | page=e5736|bibcode=2009PLoSO...4.5736A |doi-access=free }}
  • {{cite journal | title=Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase |author1=Tavarekere S Girish |author2=Eshita Sharma |author3=B Gopal | journal=FEBS Letters | date=August 2008 | volume=582 | issue=19 | pages=2923–2930 | doi=10.1016/j.febslet.2008.07.035 | pmid=18671976|s2cid=26217430 | doi-access= }}
  • {{cite journal | title=The crystal structure of a quercetin 2, 3-dioxygenase from Bacillus subtilis suggests modulation of enzyme activity by a change in the metal ion at the active site (s) |author1=B Gopal |author2=Lalima L Madan |author3=Stephen F Betz |author4=Anthony A Kossiakoff | journal=Biochemistry | date=January 2005 | volume=44 | issue=1 | pages=193–201 | doi=10.1021/bi0484421 | pmid=15628860}}
  • {{cite journal | title=Crystal structure of the transcription elongation/anti-termination factor NusA from Mycobacterium tuberculosis at 1.7 Å resolution |author1=B Gopal |author2=Lesley F Haire |author3=Steven J Gamblin |author4=Eleanor J Dodson |author5=Andrew N Lane |author6=KG Papavinasasundaram |author7=M Jo Colston |author8=Guy Dodson | journal=Journal of Molecular Biology | date=December 2001 | volume=314 | issue=5 | pages=1087–1095 | doi=10.1006/jmbi.2000.5144 | pmid=11743725}}
  • {{cite journal | title=Thermodynamics of metal ion binding and denaturation of a calcium binding protein from Entamoeba histolytica |author1=B Gopal |author2=CP Swaminathan |author3=Sudha Bhattacharya |author4=Alok Bhattacharya |author5=MRN Murthy |author6=A Surolia | journal=Biochemistry | date=September 1997 | volume=36 | issue=36 | pages=10910–10916 | doi=10.1021/bi9702546|pmid=9283081 }}

See also

{{Portal|India|Biology}}

Notes

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References

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