CCRL1
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{{Short description|Protein-coding gene in the species Homo sapiens}}
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C-C chemokine receptor type 11 is a protein that in humans is encoded by the CCRL1 gene.{{cite journal | vauthors = Khoja H, Wang G, Ng CT, Tucker J, Brown T, Shyamala V | title = Cloning of CCRL1, an orphan seven transmembrane receptor related to chemokine receptors, expressed abundantly in the heart | journal = Gene | volume = 246 | issue = 1–2 | pages = 229–38 |date=May 2000 | pmid = 10767544 | doi =10.1016/S0378-1119(00)00076-7 }}
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described.{{cite web | title = Entrez Gene: CCRL1 chemokine (C-C motif) receptor-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51554}}
References
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Further reading
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- {{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
- {{cite journal | vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |display-authors=etal}}
- {{cite journal | vauthors=Bacon KB, Schall TJ, Dairaghi DJ |title=RANTES activation of phospholipase D in Jurkat T cells: requirement of GTP-binding proteins ARF and RhoA |journal=J. Immunol. |volume=160 |issue= 4 |pages= 1894–900 |year= 1998 |doi=10.4049/jimmunol.160.4.1894 |pmid= 9469451 |doi-access=free }}
- {{cite journal | vauthors=Gosling J, Dairaghi DJ, Wang Y |title=Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK |journal=J. Immunol. |volume=164 |issue= 6 |pages= 2851–6 |year= 2000 |pmid= 10706668 |doi= 10.4049/jimmunol.164.6.2851|display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Schweickart VL, Epp A, Raport CJ, Gray PW |title=CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines |journal=J. Biol. Chem. |volume=275 |issue= 13 |pages= 9550–6 |year= 2000 |pmid= 10734104 |doi=10.1074/jbc.275.13.9550 |doi-access=free }}
- {{cite journal | vauthors=Schweickart VL, Epp A, Raport CJ, Gray PW |title=CCR11 is a functional receptor for the monocyte chemoaattractant protein family of chemokines |journal= The Journal of Biological Chemistry|volume=276 |issue= 1 |pages= 856 |year= 2001|pmid= 11134065 }}
- {{cite journal | vauthors=Townson JR, Nibbs RJ |title=Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3beta/mCCL19: comparison to human CCX-CKR |journal=Eur. J. Immunol. |volume=32 |issue= 5 |pages= 1230–41 |year= 2002 |pmid= 11981810 |doi= 10.1002/1521-4141(200205)32:5<1230::AID-IMMU1230>3.0.CO;2-L|s2cid=21911348 }}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
- {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal | vauthors=Comerford I, Milasta S, Morrow V |title=The chemokine receptor CCX-CKR mediates effective scavenging of CCL19 in vitro |journal=Eur. J. Immunol. |volume=36 |issue= 7 |pages= 1904–16 |year= 2006 |pmid= 16791897 |doi= 10.1002/eji.200535716 |s2cid=31855788 |display-authors=etal}}
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External links
- {{UCSC gene info|ACKR4}}
- {{UCSC gene info|CCR10}}
{{NLM content}}
{{Chemokine receptors}}
{{Chemokine receptor modulators}}
{{transmembranereceptor-stub}}