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CD3EAP

{{Short description|Protein-coding gene in humans}}

{{Infobox_gene}}

DNA-directed RNA polymerase I subunit RPA34 is an enzyme that in humans is encoded by the CD3EAP gene.{{cite journal | vauthors = Yamazaki T, Hamano Y, Tashiro H, Itoh K, Nakano H, Miyatake S, Saito T | title = CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells | journal = J Biol Chem | volume = 274 | issue = 26 | pages = 18173–80 |date=Jul 1999 | pmid = 10373416 | doi =10.1074/jbc.274.26.18173 | doi-access = free }}{{cite journal | vauthors = Whitehead CM, Winkfein RJ, Fritzler MJ, Rattner JB | title = ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes | journal = Chromosoma | volume = 106 | issue = 8 | pages = 493–502 |date=Mar 1998 | pmid = 9426281 | doi =10.1007/s004120050271 | s2cid = 10684078 }}{{cite journal | vauthors = Yamamoto K, Yamamoto M, Hanada K, Nogi Y, Matsuyama T, Muramatsu M | title = Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription | journal = Mol Cell Biol | volume = 24 | issue = 14 | pages = 6338–49 |date=Jun 2004 | pmid = 15226435 | pmc = 434256 | doi = 10.1128/MCB.24.14.6338-6349.2004 }}{{cite web | title = Entrez Gene: CD3EAP CD3e molecule, epsilon associated protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10849}}

Interactions

CD3EAP has been shown to interact with T-cell surface glycoprotein CD3 epsilon chain, POLR1E and POLR1C.

References

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Further reading

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  • {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
  • {{cite journal | vauthors=Bouwmeester T, Bauch A, Ruffner H |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 |s2cid=11683986 |display-authors=etal}}
  • {{cite journal | vauthors=Beausoleil SA, Jedrychowski M, Schwartz D |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 |bibcode=2004PNAS..10112130B |display-authors=etal|doi-access=free }}
  • {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
  • {{cite journal | vauthors=Ma J, Dempsey AA, Stamatiou D |title=Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects. |journal=Atherosclerosis |volume=191 |issue= 1 |pages= 63–72 |year= 2007 |pmid= 16806233 |doi= 10.1016/j.atherosclerosis.2006.05.032 |display-authors=etal}}
  • {{cite journal | vauthors=Panov KI, Panova TB, Gadal O |title=RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor. |journal=Mol. Cell. Biol. |volume=26 |issue= 14 |pages= 5436–48 |year= 2006 |pmid= 16809778 |doi= 10.1128/MCB.00230-06 | pmc=1592716 |display-authors=etal}}
  • {{cite journal | vauthors=Skjelbred CF, Saebø M, Nexø BA |title=Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study. |journal=BMC Cancer |volume=6|pages= 175 |year= 2006 |pmid= 16817948 |doi= 10.1186/1471-2407-6-175 | pmc=1533843 |display-authors=etal |doi-access=free }}
  • {{cite journal | vauthors=Beausoleil SA, Villén J, Gerber SA |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |s2cid=14294292 |display-authors=etal}}

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External links

  • {{UCSC gene info|CAST}}
  • {{UCSC gene info|CD3EAP}}

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