COG3860 RNA motif

{{primary sources|date=November 2021}}

{{Infobox rfam

| Name = COG3860

| image = RF02940.svg

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| caption = Consensus secondary structure and sequence conservation of COG3860 RNA

| Symbol = COG3860

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| Rfam = RF02940

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| RNA_type = Cis-reg

| Tax_domain =

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| SO = {{SO|0005836}}

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| EntrezGene =

| HGNCid =

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The COG3860 RNA motif is a conserved RNA structure that was discovered by bioinformatics.{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811–10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 }}

COG3860 motifs are found in Alphaproteobacteria, Betaproteobacteria, and Thermodesulfobacteriota.

Energetically stable tetraloops often occur in this motif.

COG3860 motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. Unfortunately the functions of the putatively regulated genes are not sufficiently well known to be able to hypothesize a biological function for COG3860 RNAs.