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CRYZL1

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Quinone oxidoreductase-like protein 1 is an enzyme that in humans is encoded by the CRYZL1 gene.{{cite journal | vauthors = Kim MY, Lee HK, Park JS, Park SH, Kwon HB, Soh J | title = Identification of a zeta-crystallin (quinone reductase)-like 1 gene (CRYZL1) mapped to human chromosome 21q22.1 | journal = Genomics | volume = 57 | issue = 1 | pages = 156–9 |date=Jun 1999 | pmid = 10191096 | doi = 10.1006/geno.1998.5714 }}{{cite web | title = Entrez Gene: CRYZL1 crystallin, zeta (quinone reductase)-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9946}}

This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined.

References

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External links

  • {{UCSC gene info|CRYZL1}}

Further reading

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  • {{cite journal | author=Mount SM |title=Genomic Sequence, Splicing, and Gene Annotation |journal=Am. J. Hum. Genet. |volume=67 |issue= 4 |pages= 788–92 |year= 2000 |pmid= 10986039 |doi=10.1086/303098 | pmc=1287883 }}
  • {{cite journal | author=Hattori M |title=The DNA sequence of human chromosome 21 |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518 |name-list-style=vanc| author2=Fujiyama A | author3=Taylor TD | display-authors=3 | last4=Taylor | first4=T. D. | last5=Watanabe | first5=H. | last6=Yada | first6=T. | last7=Park | first7=H.-S. | last8=Toyoda | first8=A. | last9=Ishii | first9=K. |bibcode=2000Natur.405..311H | doi-access=free }}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-style=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki | doi-access=free }}
  • {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-style=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
  • {{cite journal | author=Kimura K |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 |name-list-style=vanc| author2=Wakamatsu A | author3=Suzuki Y | display-authors=3 | last4=Ota | first4=T | last5=Nishikawa | first5=T | last6=Yamashita | first6=R | last7=Yamamoto | first7=J | last8=Sekine | first8=M | last9=Tsuritani | first9=K }}
  • {{cite journal | author=Hu YH |title=Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins |journal=BMC Genomics |volume=7|pages= 155 |year= 2006 |pmid= 16780588 |doi= 10.1186/1471-2164-7-155 | pmc=1526728 |name-list-style=vanc| author2=Warnatz HJ | author3=Vanhecke D | display-authors=3 | last4=Wagner | first4=Florian | last5=Fiebitz | first5=Andrea | last6=Thamm | first6=Sabine | last7=Kahlem | first7=Pascal | last8=Lehrach | first8=Hans | last9=Yaspo | first9=Marie-Laure |doi-access=free }}
  • {{cite journal | author=Fernández MR |title=Human and yeast zeta-crystallins bind AU-rich elements in RNA |journal=Cell. Mol. Life Sci. |volume=64 |issue= 11 |pages= 1419–27 |year= 2007 |pmid= 17497241 |doi= 10.1007/s00018-007-7091-1 |name-list-style=vanc| author2=Porté S | author3=Crosas E | display-authors=3 | last4=Barberà | first4=N. | last5=Farrés | first5=J. | last6=Biosca | first6=J. A. | last7=Parés | first7=X. |s2cid=2165411 | pmc=11136237}}

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