CYP6M2

{{Short description|Gene location in Anopheles gambiae chromosome 3R}}

{{Infobox nonhuman protein

| Organism=Anopheles gambiae

| TaxID = 7165

| Name=Cytochrome P450 6m2

| Symbol=Cyp6m2

| AltSymbols =

| UniProt=

| ECnumber = 1.14.-.-

| EntrezGene = 5668319

}}

CYP6M2 is a gene location in Anopheles gambiae chromosome 3R, involved in the insecticide resistant.{{cite journal |last1=Djouaka |first1=RF |last2=Bakare |first2=AA |last3=Coulibaly |first3=ON |last4=Akogbeto |first4=MC |last5=Ranson |first5=H |last6=Hemingway |first6=J |last7=Strode |first7=C |title=Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria. |journal=BMC Genomics |date=13 November 2008 |volume=9 |pages=538 |doi=10.1186/1471-2164-9-538 |pmid=19014539|pmc=2588609 |doi-access=free }} The enzyme encoded by this gene is capable of directly metabolizing pyrethroids,{{cite journal | vauthors = Ismail HM, O'Neill PM, Hong DW, Finn RD, Henderson CJ, Wright AT, Cravatt BF, Hemingway J, Paine MJ | display-authors = 6 | title = Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 110 | issue = 49 | pages = 19766–71 | date = December 2013 | pmid = 24248381 | pmc = 3856776 | doi = 10.1073/pnas.1320185110 | bibcode = 2013PNAS..11019766I | doi-access = free }} belongs to the cytochrome P450 family CYP6{{cite journal |last1=Wagah |first1=MG |last2=Korlević |first2=P |last3=Clarkson |first3=C |last4=Miles |first4=A |last5=Anopheles gambiae 1000 Genomes |first5=Consortium. |last6=Lawniczak |first6=MKN |last7=Makunin |first7=A |title=Genetic variation at the Cyp6m2 putative insecticide resistance locus in Anopheles gambiae and Anopheles coluzzii. |journal=Malaria Journal |date=25 May 2021 |volume=20 |issue=1 |pages=234 |doi=10.1186/s12936-021-03757-4 |pmid=34034756|pmc=8146665 |doi-access=free }}