Chlorosoman

{{Chembox

| Name = Chlorosoman

| ImageFile =Chlorosoman.png

| ImageFile1 =Chlorosoman-3D.png

| PIN = 3,3-Dimethylbutan-2-yl methylphosphonochloridate

| OtherNames = Pinacolyl methylphosphonochloridate

| Section1 = {{Chembox Identifiers

| CASNo = 7040-57-5

| PubChem = 145983

| ChemSpiderID = 128777

| SMILES = CC(C(C)(C)C)OP(=O)(C)Cl

| InChI = InChI=1S/C7H16ClO2P/c1-6(7(2,3)4)10-11(5,8)9/h6H,1-5H3

| InChIKey = XVNBZVNXJMOQEX-UHFFFAOYSA-N

}}

| Section2 = {{Chembox Properties

| C=7 | H=16| Cl=1 | O=2 | P=1

| Appearance =

| Density =

| MeltingPt =

| BoilingPt =

| Solubility = 1,030 mg/L{{cite web

| url=https://pubchem.ncbi.nlm.nih.gov/compound/145983

| title=Chlorosoman - PubChem Compound Database

| access-date=2018-05-26

| author=National Center for Biotechnology Information

| archive-date=2019-04-28

| archive-url=https://web.archive.org/web/20190428162323/https://pubchem.ncbi.nlm.nih.gov/compound/145983

| url-status=live

}}

| VaporPressure = 0.207 mm Hg

}}

| Section3 = {{Chembox Hazards

| MainHazards =

| FlashPt =

| AutoignitionPt =

}}

}}

Chlorosoman is a chlorine analog of soman. It is a highly toxic organophosphorus compound and used as the precursor substance for soman nerve agent.{{Cite journal | doi = 10.1002/slct.201702763| title = Precursors of Nerve Chemical Warfare Agents with Industrial Relevance: Characteristics and Significance for Chemical Security| journal = ChemistrySelect| volume = 3| issue = 10| pages = 2703–2715| year = 2018| last1 = Quagliano| first1 = Javier| last2 = Witkiewicz| first2 = Zygfryd| last3 = Sliwka| first3 = Ewa| last4 = Neffe| first4 = Slawomir}} Its physical properties are estimated. Soman is insoluble in water, with a boiling point of 223 degrees Celsius and a melting point of -27 degrees Celsius. Chlorosoman is at least 2.5x less toxic than its analogue.Ledgard, J. A Laboratory History of Chemical Warfare Agents.

The ClG series of compounds is used more as a precursor to highly toxic compounds. For example, soman is a precursor to EA-2613 and EA-3209.

Synthesis

ClGD follows the same synthetic route as soman, with fluoridation being omitted. Chlorosoman is prepared by the Finkelstein reaction between a solution of sodium chloride in DMF and soman.cit-OPDC. The preparatory manual to chemical warfare. Vol 1:ClG-agents. A fluoride substitution is hypothetically made by the metathetic reaction between soman, anhydrous aluminum chloride, and sodium chloride in a suitable solvent, precipitating sodium hexafluoroaluminate.

6 CH3P(O)FOCH3CHC(CH3)3 + AlCl3 + 3 NaCl-> 6 CH3P(O)ClOCH3CHC(CH3)3 + Na3AlF6v

References

{{reflist}}

{{Chemical agents}}

Category:Nerve agent precursors

Category:Pinacolyl esters

{{ester-stub}}