Colts–Jaguars rivalry

{{Main|History of the Indianapolis Colts}}

The Indianapolis Colts were established during the 1953 NFL season, originally located in Baltimore and known as the Baltimore Colts.{{cite web|url=http://colts.com/sub.cfm?page=football_dynamic&id=174|title=A look at the history of the Indianapolis Colts|access-date=July 10, 2012|archive-url=https://web.archive.org/web/20101225204727/http://www.colts.com/sub.cfm?page=football_dynamic&id=174|archive-date=December 25, 2010|url-status=dead}} Although the team experienced championship success,{{cite web |title=Indianapolis Colts Franchise Encyclopedia |url=https://www.pro-football-reference.com/teams/clt/index.htm |website=Pro Football Reference}} owner Robert Irsay threatened to move the franchise due to issues with their home venue, the Baltimore Memorial Stadium.{{cite news |last1=Attner |first1=Paul |title=Stadium Driving Irsay Up a Wall, Maybe Elsewhere |url=https://www.washingtonpost.com/archive/sports/1984/02/11/stadium-driving-irsay-up-a-wall-maybe-elsewhere/85bd5ffc-e71b-4d03-b324-82c70331e256/ |newspaper=The Washington Post |publisher=William Lewis |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20170828131637/https://www.washingtonpost.com/web/20170828131637/https://www.washingtonpost.com/archive/sports/1984/02/11/stadium-driving-irsay-up-a-wall-maybe-elsewhere/85bd5ffc-e71b-4d03-b324-82c70331e256/ |archive-date=August 28, 2017 |date=February 11, 1984}} Among the potential cities he evaluated for relocation, Jacksonville was one of them. On August 15, 1979, Irsay attended the Gater Bowl, where an enthusiastic crowd of 50,000 fans gathered to express their passion for an NFL team, waving banners and cheering in hopes of persuading him to move his team to Jacksonville.{{cite web |title=A Look Back: Colt Fever at the Gator Bowl |url=https://www.jacksonville.com/picture-gallery/sports/nfl/2019/08/15/a-look-back-colt-fever/65874268007/ |website=Jacksonville.com |publisher=Morris Comunications |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20240814175801/https://www.jacksonville.com/picture-gallery/sports/nfl/2019/08/15/a-look-back-colt-fever/65874268007/ |archive-date=August 14, 2024 |date=August 15, 2019}} This event was famously referred to as "Colts Fever," with the stadium resonating with chants of "We want the Colts."{{cite web |last1=Smits |first1=Garry |title=Colts Fever lit city's football fuse |url=https://www.jacksonville.com/story/sports/nfl/2019/08/12/nfl-eventually-caught-fever-after-jacksonvilles-pep-rally-for-colts/4459907007/ |website=Jacksonville.com |publisher=Morris Comunications |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20240921155635/https://www.jacksonville.com/story/sports/nfl/2019/08/12/nfl-eventually-caught-fever-after-jacksonvilles-pep-rally-for-colts/4459907007/ |archive-date=September 21, 2024 |date=August 12, 2019}}{{cite web |last1=Kouvaris |first1=Sam |title=Colt Fever 40 Years Ago Was the Start |url=https://www.samsportsline.com/colt-fever-40-years-ago-was-the-start/ |website=SamSportsLine |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20201129021650/https://www.samsportsline.com/colt-fever-40-years-ago-was-the-start/ |archive-date=November 29, 2020 |date=August 2, 2019}} Despite the overwhelming support, Irsay ultimately decided on Indianapolis as the new home for the team, which became known as the Indianapolis Colts in the 1984 season.{{cite web |title=CHRONOLOGY OF COLTS' MOVE TO INDIANAPOLIS |url=https://www.baltimoresun.com/1994/03/29/chronology-of-colts-move-to-indianapolis/ |website=Baltimore Sun |publisher=Trif Alatzas |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20240613162319/https://www.baltimoresun.com/1994/03/29/chronology-of-colts-move-to-indianapolis/ |archive-date=June 13, 2024 |date=March 29, 1994}} Since their relocation, the team has struggled, making the playoffs only once in the 1987 season.

{{Main|History of the Jacksonville Jaguars}}

In 1991, Jacksonville made another attempt to secure an NFL franchise when the NFL revealed its intention to introduce two new expansion teams. The newly formed ownership group, Touchdown Jacksonville!, submitted a proposal to obtain a team for the city.{{cite web |title=Jaguars: The road to the franchise's birth |url=https://www.jacksonville.com/picture-gallery/sports/nfl/2018/11/28/jaguars-the-road-to-the/67970566007/ |website=Jacksonville.com |publisher=Morris Communications |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20240131104303/https://www.jacksonville.com/picture-gallery/sports/nfl/2018/11/28/jaguars-the-road-to-the/67970566007/ |archive-date=January 31, 2024 |date=November 28, 2018}} Although they faced challenges and were not the frontrunners compared to other cities, the NFL ultimately voted to award Jacksonville an expansion team on November 30, 1993.{{cite web |last1=Stellino |first1=Vito |title=Twenty years ago, how upstart Jacksonville won an NFL franchise |url=https://www.jacksonville.com/story/sports/nfl/2013/12/02/twenty-years-ago-how-upstart-jacksonville-won-nfl-franchise/15807332007/ |website=Jacksonville.com |publisher=Morris Communications |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20220924225536/https://www.jacksonville.com/story/sports/nfl/2013/12/02/twenty-years-ago-how-upstart-jacksonville-won-nfl-franchise/15807332007/ |archive-date=September 24, 2022 |date=December 1, 2013}} Consequently, the Jacksonville Jaguars were established to compete in the NFL starting in the 1995 season, joining the AFC alongside the Indianapolis Colts.{{cite web |last1=Litsky |first1=Frank |title=PRO FOOTBALL; N.F.L. Expansion Surprise: Jacksonville Jaguars |url=https://www.nytimes.com/1993/12/01/sports/pro-football-nfl-expansion-surprise-jacksonville-jaguars.html |website=The New York Times |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20091125065345/https://www.nytimes.com/1993/12/01/sports/pro-football-nfl-expansion-surprise-jacksonville-jaguars.html |archive-date=November 25, 2009 |date=December 1, 1993}} However, they joined the AFC Central, rather than the AFC East where the Colts where.{{cite web |title=1995 NFL Division Standings |url=https://www.nfl.com/standings/division/1995/reg |website=NFL.com |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20200606134943/https://www.nfl.com/standings/division/1995/reg/ |archive-date=June 6, 2020}}

In the 1995 season, the inaugural game between the Colts and Jaguars took place on December 10 in Jacksonville.{{cite web |title=JACKSONVILLE JAGUARS (3-10)VS.INDIANAPOLIS COLTS (7-6)Sunday, December 10, 1995, 1:00 |url=https://www.jaguars.com/news/jacksonville-jaguars-3-10-vs-indianapolis-colts-7-6-sunday-december-10-1-5848184 |website=Jacksonville Jaguars |access-date=14 August 2024 |archive-url=https://web.archive.org/web/20210516183911/https://www.jaguars.com/news/jacksonville-jaguars-3-10-vs-indianapolis-colts-7-6-sunday-december-10-1-5848184 |archive-date=May 16, 2021 |date=December 3, 1995}} The 3–10 Jaguars struggled against the 7–6 Colts, as issues with their special teams resulted in 14 Colts points, creating a deficit they were unable to overcome. This ultimately culminated in a 41–31 Colts victory in their inaugural matchup.{{cite web |title=Colts 41, Jaguars 31 |url=https://www.upi.com/Archives/1995/12/10/Colts-41-Jaguars-31/7815487800162/ |website=UPI.com |access-date=24 September 2024 |date=December 10, 1995}} This victory helped the Colts to secure a playoff berth for the first time since their 1987 season.

From 1996 to 1999, the two teams did not face each other in the regular season. However, they both qualified for the playoffs in the same season twice in 1996 and 1999.

During the 1996 season playoffs, the Colts were defeated by the Pittsburgh Steelers, whereas the Jaguars unexpectedly advanced to the AFC Championship by overcoming the Buffalo Bills and the Denver Broncos, only to fall to the New England Patriots.{{cite web |title=National Football League (NFL) 1996 NFL Playoffs |url=https://www.retroseasons.com/leagues/nfl/1996/playoffs/ |website=Retro Seasons |date=21 March 2023 |access-date=14 August 2024 |archive-url=https://web.archive.org/web/20240814203745/https://www.retroseasons.com/leagues/nfl/1996/playoffs/ |archive-date=August 14, 2024}}

During the 1999 season playoffs, the Jaguars and Colts secured the 1st and 2nd seeds in the AFC, respectively. The Jaguars defeated the Miami Dolphins, but both teams ultimately fell to the Tennessee Titans.{{cite web |title=National Football League (NFL) 1999 NFL Playoffs |url=https://www.retroseasons.com/leagues/nfl/1999/playoffs/ |website=Retro Seasons |access-date=2 September 2024 |archive-url=https://web.archive.org/web/20210121120713/https://www.retroseasons.com/leagues/nfl/1999/playoffs/ |archive-date=January 21, 2021}}

In the 2000 season on September 25, the Colts and Jaguars faced off for the first time in Indianapolis. The Jaguars arrived at the game having the 7th-ranked defense and fresh off their first shutout in franchise history against the Cincinnati Bengals.{{cite web |title=Manning's 440 yards lead Colts over Jags, 43 - 14 |url=https://www.newson6.com/story/5e3684942f69d76f62099c41/mannings-440-yards-lead-colts-over-jags-43--14 |website=NewsOn6 |access-date=15 August 2024 |archive-url=https://web.archive.org/web/20200925203534/https://www.newson6.com/story/5e3684942f69d76f62099c41/mannings-440-yards-lead-colts-over-jags-43--14 |archive-date=September 25, 2020 |date=September 26, 2000}} However, future hall–of–famer QB Peyton Manning, drafted first overall by the Colts in the 1998 NFL Draft, had one of his best performances yet. He threw for 440 yards and four touchdowns, leading the Colts to a dominant 43–14 win.{{cite web |title=Colts star, but it's Manning's show |url=https://www.espn.com/nfl/2000/20000925/recap/jacind.html |website=ESPN |publisher=The Walt Disney Company |access-date=25 August 2024 |archive-url=https://web.archive.org/web/20240814223246/https://www.espn.com/nfl/2000/20000925/recap/jacind.html |archive-date=August 14, 2024 |date=September 25, 2000 |url-status=live}}

Following the NFL's approval for the creation of the Houston Texans, the league opted to reorganize into eight divisions: four teams in each division and four divisions in each conference, effective in the 2002 season. In the newly established AFC South division, the NFL incorporated the following teams: the newly formed Houston Texans, the Jacksonville Jaguars and Tennessee Titans from the AFC Central, and the Indianapolis Colts from the AFC East.{{cite web |title=New NFL alignment created for 2002 |url=https://www.deseret.com/2001/5/22/19587654/new-nfl-alignment-created-for-2002/ |website=Deseret News |publisher=Burke Olsen |access-date=19 June 2024 |archive-url=https://web.archive.org/web/20201221134711/https://www.deseret.com/2001/5/22/19587654/new-nfl-alignment-created-for-2002/ |archive-date=December 21, 2020 |date=May 21, 2001}} Initially, the NFL offered Wayne Huizenga, owner of the Dolphins, the opportunity to move to the more geographically suitable AFC South over the Colts, potentially fostering an in-state rivalry with the Jaguars.{{cite web |last1=Graham |first1=Tim |title=The Dolphins had the option to join the AFC South. Revisiting what could have been |url=https://www.nytimes.com/athletic/3641340/2022/09/30/dolphins-nfl-division-realignment/ |website=The Athletic |publisher=The New York Times Company |access-date=14 August 2024 |archive-url=https://web.archive.org/web/20240523174454/https://www.nytimes.com/athletic/3641340/2022/09/30/dolphins-nfl-division-realignment/ |archive-date=May 23, 2024 |date=September 30, 2022}} However, Huizenga chose to maintain the traditional AFL rivalries within the AFC East. Consequently, the Colts and Jaguars became divisional rivals, meeting twice annually – once in Indianapolis and once in Jacksonville.

File:Peyton Manning Miami Super Bowl XLIV team photo.jpg consistently excelled against them, achieving a 14–5 record as a Colts player and significantly contributing to the Colts success throughout the 2000s.]]

In the 2002 season, the Colts and Jaguars faced off for the first time as divisional rivals in their season opener on September 8 in Jacksonville. The Colts initiated the scoring with a touchdown in the first quarter. The Jaguars tied it in the second quarter. In the final minutes of the second quarter, Mark Brunell threw a 40–yard pick–six to LB Marcus Washington. The Jaguars then missed a 52–yard field goal attempt, resulting in a halftime score of 14–7 in favor of the Colts. In the third quarter, a fumble by Colts RB Edgerrin James led to a Jaguars' field goal, followed by another fumble from Colts TE Marcus Pollard that led to a Jaguars touchdown, giving them the lead. However, after the Jaguars forced a Colts three–and–out, return specialist Damon Gibson mishandled the catch, allowing Colts DB Clifton Crosby to recover the ball at Jacksonville's 19–yard line. The Colts capitalized on this opportunity, scoring a touchdown to regain the lead. In the fourth quarter, the Colts added another touchdown to widen their advantage. The Jaguars mounted a lengthy drive, scoring a touchdown and converting a two-point attempt to narrow the Colts' lead. The Colts effectively managed the Jaguars' timeouts, leaving them with the ball and about a minute remaining. The Jaguars advanced to the Colts' 46–yard line but ultimately ran out of time, resulting in a 28–25 victory for the Colts.{{cite web |title=Indianapolis Colts at Jacksonville Jaguars - September 8th, 2002 |url=https://www.pro-football-reference.com/boxscores/200209080jax.htm |website=Pro Football Reference |access-date=16 August 2024 |archive-url=https://web.archive.org/web/20190226014549/https://www.pro-football-reference.com/boxscores/200209080jax.htm |archive-date=February 26, 2019 |url-status=live}}{{cite web |last1=Sullivan |first1=Tim |title=Jaguars pay for mistakes |url=https://www.gainesville.com/story/news/2002/09/09/jaguars-pay-for-mistakes/31614389007/ |website=The Gainesville Sun |publisher=Rynni Henderson |access-date=16 August 2024 |archive-url=https://web.archive.org/web/20240816171819/https://www.gainesville.com/story/news/2002/09/09/jaguars-pay-for-mistakes/31614389007/ |archive-date=August 16, 2024 |date=September 9, 2002 |url-status=live}}

The two teams faced off in the season finale on December 30 in Indianapolis. Although the Colts had lost the inaugural AFC South title to the Titans the week prior, they still have the opportunity to secure a playoff berth with a victory against the eliminated Jaguars.{{cite web |last1=Penner |first1=Mike |title=Playoff Picture Still Out of Focus |url=https://www.latimes.com/archives/la-xpm-2002-dec-23-sp-penner23-story.html |website=Los Angeles times |access-date=16 August 2024 |archive-url=https://web.archive.org/web/20240816220239/https://www.latimes.com/archives/la-xpm-2002-dec-23-sp-penner23-story.html |archive-date=August 16, 2024 |date=December 23, 2002 |url-status=live}} The Jaguars had a 13–10 lead heading into the fourth quarter. On the subsequent drive, the Jaguars appeared to force a three–and–out, but a penalty for running into the kicker granted the Colts a fresh set of downs. Capitalizing on this opportunity, the Colts tied the game with a field goal. After forcing another three–and–out, a strong punt return positioned the Colts at Jacksonville's 47–yard line. Manning then connected with Pollard for an 11–yard touchdown, putting the Colts ahead. In the closing moments, the Colts' defense held firm, securing a 20–13 victory over the Jaguars, completing a sweep in their initial matchups as divisional rivals and earning a wild card spot in the playoffs.{{cite web |last1=Marot |first1=Michael |title=Colts Kick Jaguars 20-13 |url=https://www.ourmidland.com/news/article/Colts-Kick-Jaguars-20-13-7151217.php |website=Midland Daily News |publisher=Hearst Corporation |access-date=16 August 2024 |archive-url=https://web.archive.org/web/20240620223204/https://www.ourmidland.com/news/article/Colts-Kick-Jaguars-20-13-7151217.php |archive-date=June 20, 2024 |date=December 28, 2002 |url-status=live}}

In the 2003 season, the Colts secured a 23–13 victory over the Jaguars on September 21 in Indianapolis, marking their fifth consecutive win against their rival.{{cite web |last1=Max |first1=Nathan |title=AMAZING WAYNE DOOMS THE JAGS |url=https://www.orlandosentinel.com/2003/09/22/amazing-wayne-dooms-the-jags/ |website=Orlando Sentinel |publisher=Paul Pham |access-date=22 August 2024 |archive-url=https://web.archive.org/web/20240821215906/https://www.orlandosentinel.com/2003/09/22/amazing-wayne-dooms-the-jags/ |archive-date=August 21, 2024 |date=September 22, 2003}} A standout moment from the game occurred when Colts' rookie DB Mike Doss caused Jaguars' RB Fred Taylor to fumble the ball. Doss reportedly quipped, "Hey, Fred, you forgot something." In retaliation, Taylor told reporters ahead of their next encounter, "I'm going to bust his (butt). I'm going to punish him."{{cite web |title=Taylor said it, did it |url=https://www.jaguars.com/news/taylor-said-it-did-it-5836983 |website=Jacksonville Jaguars |access-date=22 August 2024 |archive-url=https://web.archive.org/web/20221007161253/https://www.jaguars.com/news/taylor-said-it-did-it-5836983 |archive-date=October 7, 2022 |date=November 9, 2003}}

The two teams faced off again on November 9 in Jacksonville, with the Colts holding a 7–1 record and the Jaguars at 1–7. As the fourth quarter commenced, the Jaguars, trailing by 13 points, mounted a comeback to take the lead. The Colts briefly regained the lead with a field goal. However, Fred Taylor fulfilled his promise with a 32–yard run, evading Mike Doss as he fell, and reached the end zone, putting the Jaguars ahead with just one minute left in the game. The Jaguars then intercepted Manning, securing a 28–23 victory over the Colts in a stunning upset and recording their first win over the Colts. Taylor concluded the game with 152 rushing yards on 28 carries. After the game, Doss remarked, "I guess you'd have to say he got the final word today."{{cite web |last1=Pells |first1=Eddie |title=Taylor Lifts Jaguars Past Colts for Upset Victory |url=https://www.theledger.com/story/news/2003/11/10/taylor-lifts-jaguars-past-colts-for-upset-victory/26083246007/ |website=The Ledger |publisher=Leon Tucker |access-date=22 August 2024 |archive-url=https://web.archive.org/web/20240822161104/https://www.theledger.com/story/news/2003/11/10/taylor-lifts-jaguars-past-colts-for-upset-victory/26083246007/ |archive-date=August 22, 2024 |location=Lakeland, Florida |date=November 10, 2003 |url-status=live}}

In the 2004 season, The Colts and Jaguars faced off on October 24 in Indianapolis. The Colts were favored by 9 points against the Jaguars as they entered the game, having already won in their earlier matchup on October 3 in Jacksonville.{{cite web |title=Manning Picks the Jaguars Apart |url=https://www.latimes.com/archives/la-xpm-2004-oct-04-sp-colts4-story.html |website=Los Angeles Times |access-date=22 August 2024 |archive-url=https://web.archive.org/web/20240822171340/https://www.latimes.com/archives/la-xpm-2004-oct-04-sp-colts4-story.html |archive-date=August 22, 2024 |date=October 4, 2004 |url-status=live}} The game was fiercely competitive, highlighted by Jaguars QB Byron Leftwich having one of his best games, throwing for 300 yards and two touchdowns. In the final minutes, after the Colts managed to tie the game, Leftwich guided the Jaguars into Colts territory, culminating in rookie K Josh Scobee successfully making a game-winning 53–yard field goal, upsetting the Colts in a 27-24 Jaguars victory and recording their first win in Indianapolis.{{cite web |title=Jaguars tame the Colts |url=https://www.spokesman.com/stories/2004/oct/25/jaguars-tame-the-colts/ |website=The Spokesman-Review |publisher=William Stacey Cowles |access-date=23 August 2024 |archive-url=https://web.archive.org/web/20240823145544/https://www.spokesman.com/stories/2004/oct/25/jaguars-tame-the-colts/ |archive-date=August 23, 2024 |date=October 25, 2004 |url-status=live}} This would ultimately be the Colts' only loss at the RCA Dome that season.

The Colts embarked on a winning streak that ultimately secured them the AFC South title,{{cite web |title=Colts clinch AFC South |url=https://www.capecodtimes.com/story/sports/2004/12/13/colts-clinch-afc-south/50914871007/ |website=Cape Cod Times |publisher=Local Media Group |access-date=23 August 2024 |archive-url=https://web.archive.org/web/20220529024439/https://www.capecodtimes.com/story/sports/2004/12/13/colts-clinch-afc-south/50914871007/ |archive-date=May 29, 2022 |date=December 13, 2004}} and were locked in the 3rd seed after a 34–31 overtime victory over the San Diego Chargers as they entered the final week.{{cite web |title=Colts 34, Chargers 31, Overtime |url=https://www.wthr.com/article/sports/colts-34-chargers-31-overtime/531-05044588-4383-4fc7-a4bc-6d9c7895e491 |website=WTHR |access-date=23 August 2024 |archive-url=https://web.archive.org/web/20240823172106/https://www.wthr.com/article/sports/colts-34-chargers-31-overtime/531-05044588-4383-4fc7-a4bc-6d9c7895e491 |archive-date=August 23, 2024 |date=December 27, 2004 |url-status=live}} In contrast, the Jaguars were still in the hunt for a playoff berth. For the Jaguars to secure the last playoff position, they not only needed to win their game against the Oakland Raiders but also required the Colts to beat the Broncos and the Steelers to beat the Bills. If all conditions were met, the Jaguars would head to Indianapolis for their first playoff matchup against the Colts.{{cite web |title=2004 NFL PLAYOFF SCENARIOS |url=https://www.nfl.info/nflmedia/News/2004News/2004nflplayoffscenarios17A.htm |website=NFL.com |access-date=23 August 2024 |archive-url=https://web.archive.org/web/20240823173657/https://www.nfl.info/nflmedia/News/2004News/2004nflplayoffscenarios17A.htm |archive-date=August 23, 2024 |date=December 28, 2004 |url-status=live}} The Jaguars defeated the Raiders, and the Steelers defeated the Bills.{{cite web |title=Steelers Make History, While Bills Are History |url=https://www.latimes.com/archives/la-xpm-2005-jan-03-sp-steelers3-story.html |website=Los Angeles Times |access-date=23 August 2024 |archive-url=https://web.archive.org/web/20201230225635/https://www.latimes.com/archives/la-xpm-2005-jan-03-sp-steelers3-story.html |archive-date=December 30, 2020 |date=January 3, 2005}} However, the Colts opted to rest their starters, ultimately losing 33–14. This outcome allowed the Broncos to clinch the final 6th seed, resulting in the elimination of the Jaguars.{{cite web |title=Bronco Victory Earns Them a Colt Rematch |url=https://www.latimes.com/archives/la-xpm-2005-jan-03-sp-broncos3-story.html |website=Los Angeles Times |access-date=23 August 2024 |archive-url=https://web.archive.org/web/20240823202058/https://www.latimes.com/archives/la-xpm-2005-jan-03-sp-broncos3-story.html |archive-date=August 23, 2024 |date=January 3, 2005}} After the game, Jaguars players suggested that the Colts were apprehensive about facing Jacksonville and deliberately lost to the Broncos, with LB Mike Peterson stating, “They didn’t want to play us.” Subsequently, the Colts defeated the Broncos 49–24 in the wild-card round.

In the 2005 season, the Jaguars' defense limited Peyton Manning to one of his worst performances in his career on September 18 in Indianapolis. He threw for 122 yards and no touchdowns, resulting in a 44.0 passer rating. However, the Jaguars' offense also struggled significantly, managing only a field goal. The decisive drive occurred in the fourth quarter, during which the Jaguars allowed Edgerrin James to gain 63 yards on an 88-yard touchdown drive, resulting in a 10–3 win for the Colts.{{cite web |title=Jaguars sacked by Colts |url=https://www.jaguars.com/news/jaguars-sacked-by-colts-5836812 |website=Jacksonville Jaguars |access-date=24 August 2024 |archive-url=https://web.archive.org/web/20210514110834/https://www.jaguars.com/news/jaguars-sacked-by-colts-5836812 |archive-date=May 14, 2021 |date=September 18, 2005}}

The two teams again faced off on December 11 in Jacksonville, both vying for the AFC South title. The Colts entered the matchup riding a 12–game winning streak, remaining undefeated, while the Jaguars boasted a 9–3 record. However, the Jaguars struggled to match the Colts' performance, as the Colts jumped to a 26–3 lead before ultimately winning 26–18. This win not only clinched the AFC South for the Colts but also granted them a first-round bye, home-field advantage throughout the playoffs and extended their winning streak to 13 games. Additionally, they achieved a sweep of the AFC South for the first time in franchise history.{{cite web |last1=Brown |first1=Clifton |title=Another Giant Step for Manning and Undefeated Colts |url=https://www.nytimes.com/2005/12/12/sports/football/another-giant-step-for-manning-and-undefeated-colts.html |website=New York Times |access-date=27 August 2024 |archive-url=https://web.archive.org/web/20150529181705/https://www.nytimes.com/2005/12/12/sports/football/another-giant-step-for-manning-and-undefeated-colts.html |archive-date=May 29, 2015 |date=December 12, 2005}}

Despite being swept, the Jaguars secured their first playoff appearance since 1999 with a victory over the Texans.{{cite web |title=Jaguars roll into playoffs |url=https://www.gainesville.com/story/news/2005/12/25/jaguars-roll-into-playoffs/31470117007/ |website=The Gainesville Sun |publisher=Rynni Henderson |access-date=25 August 2024 |date=December 24, 2005}} In the playoffs, the Jaguars were eliminated by the Patriots,{{cite web |title=Patriots look like champions again |url=https://1259.newstogo.us/2006/01/08/patriots-look-like-champions-again/ |website=Southern Standard |access-date=25 August 2024 |archive-url=https://web.archive.org/web/20240825013110/https://1259.newstogo.us/2006/01/08/patriots-look-like-champions-again/ |archive-date=August 25, 2024 |date=January 8, 2006 |url-status=live}} whereas the Colts experienced a surprising defeat in a notable game against the eventual Super Bowl champions Steelers.{{cite web |last1=Flaherty |first1=Dan |title=The 2005 Pittsburgh Steelers: 6-Seed Magic |url=https://ouatsports.com/the-2005-pittsburgh-steelers-sports-history-articles/ |website=Once Upon a Time Sports |date=13 June 2014 |access-date=25 August 2024 |archive-url=https://web.archive.org/web/20240825013323/https://ouatsports.com/the-2005-pittsburgh-steelers-sports-history-articles/q |archive-date=August 25, 2024 |url-status=live}}

{{multiple image|footer= The Jaguars gained a reputation for their strong rushing performance against the Colts. Notably, in a game from the 2006 season, running backs Maurice Jones-Drew (left) and Fred Taylor (right) rushed for 166 yards and 131 yards, respectively. Their combined efforts contributed to the Jaguars setting a franchise record of 375 rushing yards in a single game, which also marked the most rushing yards allowed by the Colts in their franchise history.|align=left|image1=Mjd.jpg|alt1=Maurice Jones-Drew|width1=135|image2=Fred Taylor Jacksonville Jaguar Headshot.JPG|alt2=Fred Taylor|length2=200|width2=235}}

During the 2006 season, the Jaguars established a franchise record for total rushing yards during their game against the Colts on December 10 in Jacksonville. The Colts had previously defeated the Jaguars 21–14 in their earlier matchup on September 24 in Indianapolis,{{cite web |last1=Battista |first1=Judy |title=Colts Teach the Jaguars a Lesson in Winning |url=https://www.nytimes.com/2006/09/25/sports/football/colts-teach-the-jaguars-a-lesson-in-winning.html |website=New York Times |access-date=25 August 2024 |archive-url=https://web.archive.org/web/20240825021855/https://www.nytimes.com/2006/09/25/sports/football/colts-teach-the-jaguars-a-lesson-in-winning.html |archive-date=August 25, 2024 |date=September 25, 2006 |url-status=live}} and a victory in this matchup would secure them the AFC South.{{cite web |title=Jags run away from Colts, win 44-17 |url=https://www.nfl.com/news/jags-run-away-from-colts-win-44-17-09000d5d800584e4 |website=NFL.com |access-date=26 September 2024 |archive-url=https://web.archive.org/web/20200923061333/https://www.nfl.com/news/jags-run-away-from-colts-win-44-17-09000d5d800584e4 |archive-date=September 23, 2020 |date=December 10, 2006 |url-status=live}} Against the league's worst rushing defense, the Jaguars amassed 375 rushing yards en route to a 44–17 win and a franchise record for most total rushing yards in a game,{{cite web |title=Most team rush yards in a game by Jaguars |url=https://www.statmuse.com/nfl/ask/most-team-rush-yards-in-a-game-by-jaguars |website=Statmuse}} while the Colts set a new franchise record for the most rushing yards allowed in a game.{{cite web |title=Colts most rushing yards allowed in a game |url=https://www.statmuse.com/nfl/ask/colts-most-rushing-yards-allowed-in-a-game |website=Statmuse}} Jaguars' RBs Maurice Jones-Drew led the charge with 166 rushing yards on 15 carries with two touchdowns, Fred Taylor added 131 rushing yards on 9 carries with one touchdown, and Alvin Pearman contributed 71 rushing yards on 13 carries with one touchdown.{{cite web |title=Fred Taylor and Maurice Jones-Drew Run Rampant Colts vs. Jaguars (Week 14, 2006);NFL Full Game |url=https://www.youtube.com/watch?v=eO21gTstuPM |website=Youtube |publisher=NFL |access-date=1 September 2024 |archive-url=https://web.archive.org/web/20161007063601/https://www.youtube.com/watch?v=eO21gTstuPM |archive-date=October 7, 2016 |date=September 30, 2016 |url-status=live}} Additionally, Maurice Jones-Drew amassed 303 all-purpose yards, setting a franchise record for most all-purpose yards in a game.{{cite web |title=Most all-purpose yards by a Jagaurs player in a game |url=https://www.statmuse.com/nfl/ask?q=most+all-purpose+yards+by+a+jagaurs+player+in+a+game |website=Statmuse}}

Despite improving to an 8–5 record with their win, the Jaguars lost their last three games and failed to qualify for the playoffs.{{cite web |last1=Freeman |first1=Clayton |title=Heartbreak in the 904: 5 worst end-of-year collapses in Jacksonville Jaguars history |url=https://www.jacksonville.com/story/sports/nfl/2024/01/08/jacksonville-jaguars-worst-late-season-collapses-in-nfl-football/72148220007/ |website=Jacksonville.com |access-date=27 August 2024 |archive-url=https://web.archive.org/web/20240130224347/https://www.jacksonville.com/story/sports/nfl/2024/01/08/jacksonville-jaguars-worst-late-season-collapses-in-nfl-football/72148220007/ |archive-date=January 30, 2024 |date=January 8, 2024}} In contrast, the Colts rebounded and concluded the season with a 12–4 record and secured the 3rd seed. In the playoffs, they went on to defeat the Kansas City Chiefs, Baltimore Ravens, and Patriots to reach their third Super Bowl appearance. In Super Bowl XLI, the Colts defeated the Chicago Bears 29–17, securing their second Super Bowl Championship and their first in Indianapolis.{{cite web |last1=Rietmann |first1=Tom |title=COLTS SEASON IN REVIEW: 2006 |url=https://www.colts.com/news/colts-season-in-review-2006-10270019 |website=Colts |access-date=28 June 2024 |archive-url=https://web.archive.org/web/20210418040015/https://www.colts.com/news/colts-season-in-review-2006-10270019 |archive-date=April 18, 2021 |date=July 16, 2013}}

Both teams began the 2007 season with good records; however, during their first encounter on October 22 in Jacksonville, the defending Super Bowl champions Colts aimed to rectify their last season defeat, successfully limiting the Jaguars' running backs to a decisive 29–7 victory in a Monday Night Football matchup. Following the game, Manning would later remark that they "put a lot of emphasis on this game."{{cite web |last1=Long |first1=Mark |title=Manning, Colts control Jaguars, 29-7 |url=https://www.tuscaloosanews.com/story/sports/2007/10/23/manning-colts-control-jaguars-29-7/27730031007/ |website=Tuscaloosanews |access-date=27 August 2024 |archive-url=https://web.archive.org/web/20240827032014/https://www.tuscaloosanews.com/story/sports/2007/10/23/manning-colts-control-jaguars-29-7/27730031007/ |archive-date=August 27, 2024 |date=October 23, 2007 |url-status=live}}

Both teams were competing for the AFC South when they met again on December 2 in Indianapolis, marking their last matchup at the RCA Dome. The Jaguars entered the game with an 8–3 record, while the Colts boasted a 9–2 record. The match remained competitive throughout; but the Colts emerged victorious with a narrow 28–25 win, completing a season sweep over the Jaguars.{{cite web |last1=Battista |first1=Judy |title=Colts Add Distance and Subtract Some Stress |url=https://www.nytimes.com/2007/12/03/sports/football/03colts.html |website=New York Times |access-date=29 August 2024 |archive-url=https://web.archive.org/web/20150605035602/https://www.nytimes.com/2007/12/03/sports/football/03colts.html |archive-date=June 5, 2015 |date=December 3, 2007}}

The Colts clinched the AFC South title and the 2nd seed after defeating the Raiders, coupled with the Steelers loss to the Jaguars.{{cite web |last1=Dubow |first1=Josh |title=NFL: Colts clinch playoff bye with win over Raiders |url=https://the.honoluluadvertiser.com/article/2007/Dec/16/br/br1602849573.html |website=Honolulu Advertiser |publisher=Dennis Francis |access-date=27 August 2024 |archive-url=https://web.archive.org/web/20071226011913/https://the.honoluluadvertiser.com/article/2007/Dec/16/br/br1602849573.html |archive-date=December 26, 2007 |date=December 16, 2007}} The following week, the Jaguars earned the 5th seed with a victory against the Raiders.{{cite web |title=Jaguars clinch playoff spot |url=https://www.jaguars.com/news/jaguars-clinch-playoff-spot-5840496 |website=Jacksonville Jaguars |access-date=27 August 2024 |archive-url=https://web.archive.org/web/20200927133826/https://www.jaguars.com/news/jaguars-clinch-playoff-spot-5840496 |archive-date=September 27, 2020 |date=December 23, 2007}} In the playoffs, the Colts were defeated by the Chargers, while the Jaguars defeated the Steelers but fell to the undefeated Patriots.{{cite web |title=2007 NFL Playoffs |url=https://www.retroseasons.com/leagues/NFL/2007/playoffs/ |website=Retro Seasons |access-date=27 August 2024 |archive-url=https://web.archive.org/web/20210116152027/https://www.retroseasons.com/leagues/NFL/2007/playoffs/ |archive-date=January 16, 2021}}

Entering the 2008 season, analysts predicted a competitive race in the AFC South, primarily between the Jaguars and the Colts, with several experts favoring the Jaguars to emerge victorious.{{cite web |last1=Augustin |first1=Paul, Jr. |title=2008 NFL Predictions: The AFC |url=https://bleacherreport.com/articles/32014-2008-nfl-predictions-the-afc |website=Bleacher Report |publisher=Turner Broadcasting System |access-date=28 August 2024 |archive-url=https://web.archive.org/web/20240828185221/https://bleacherreport.com/articles/32014-2008-nfl-predictions-the-afc |archive-date=August 28, 2024 |date=June 23, 2008 |url-status=live}}{{cite web |last1=Banks |first1=Don |title=Predicting the 2008 NFL season |url=https://www.si.com/more-sports/2008/08/29/predictions |website=SI |access-date=28 August 2024 |archive-url=https://web.archive.org/web/20170917170152/https://www.si.com/more-sports/2008/08/29/predictions |archive-date=September 17, 2017 |date=August 29, 2008}} The Colts faced off against the Jaguars on September 21 at the newly built Lucas Oil Stadium in Indianapolis. In a manner reminiscent of their 2004 victory, Josh Scobee kicked a game-winning 51-yard field goal in the final seconds, securing a 23–21 victory for the Jaguars.{{cite web |title=Scobee saves game for Jags in 23-21 win over Colts |url=https://www.deseret.com/2008/9/22/20276189/scobee-saves-game-for-jags-in-23-21-win-over-colts/ |website=Deseret News |publisher=Deseret News Publishing Company |access-date=28 August 2024 |archive-url=https://web.archive.org/web/20240828145559/https://www.deseret.com/2008/9/22/20276189/scobee-saves-game-for-jags-in-23-21-win-over-colts/ |archive-date=August 28, 2024 |date=September 21, 2008}}

They met again on December 18 in Jacksonville for a Thursday Night Football matchup. The Jaguars were eliminated from contention due to subpar performance and injuries,{{cite web |last1=Rage |first1=River City |title=2008 Season Retrospective: Did injuries "Neg Out" the Jaguars? |url=https://www.bigcatcountry.com/2009/7/21/954644/2008-season-retrospective-did |website=Big Cat Country |publisher=Vox Media |access-date=28 August 2024 |archive-url=https://web.archive.org/web/20121124011858/https://www.bigcatcountry.com/2009/7/21/954644/2008-season-retrospective-did |archive-date=November 24, 2012 |date=July 21, 2009}} while the Colts saw their consecutive AFC South title streak come to an end at the hands of the Titans.{{cite web |title=Titans clinch first AFC South title since 2002 |url=https://www.sandiegouniontribune.com/2008/12/07/titans-clinch-first-afc-south-title-since-2002/ |website=The San Diego Union-Tribune |publisher=Ron Hasse |access-date=18 July 2024 |archive-url=https://web.archive.org/web/20240718203356/https://www.sandiegouniontribune.com/2008/12/07/titans-clinch-first-afc-south-title-since-2002/ |archive-date=July 18, 2024 |date=December 7, 2008}} Nevertheless, a victory for the Colts in this matchup would clinch a playoff spot. Trailing by 10 points as they entered the fourth quarter, Manning led a comeback for the Colts, and a pick-six allowed them to take the lead, winning 31–24 and clinching the 5th seed in the playoffs.{{cite web |title=Manning, Colts beat Jags to clinch wild card spot |url=https://www.sandiegouniontribune.com/2008/12/19/manning-colts-beat-jags-to-clinch-wild-card-spot/ |website=The San Diego Union-Tribune |publisher=Ron Hasse |access-date=28 August 2024 |archive-url=https://web.archive.org/web/20240828184454/https://www.sandiegouniontribune.com/2008/12/19/manning-colts-beat-jags-to-clinch-wild-card-spot/ |archive-date=August 28, 2024 |date=December 19, 2008}}

In the 2009 season, the Colts achieved one of the most impressive beginnings in NFL history. Approaching their Thursday Night Football game against the Jaguars on December 17 in Jacksonville, the Colts boasted a 13–0 record and a remarkable 22–game regular season winning streak that extended from the prior season. Despite already securing home-field advantage for the playoffs after last week's victory over the Broncos, they opted to field nearly all their starters against the Jaguars, who were fighting to maintain their playoff hopes.{{cite web |title=COLTS-JAGUARS PREVIEW |url=https://www.colts.com/news/colts-jaguars-preview-5349011 |website=Indianapolis Colts |access-date=30 August 2024 |archive-url=https://web.archive.org/web/20211018035800/https://www.colts.com/news/colts-jaguars-preview-5349011 |archive-date=October 18, 2021 |date=December 17, 2009}} This highly anticipated game led to a sellout crowd at the Jacksonville Municipal Stadium, marking the only time that season. The offensive showdown featured no punts until the fourth quarter and multiple lead changes. Ultimately, the decisive moment came when Manning connected with WR Reggie Wayne for a 65–yard touchdown pass, allowing the Colts to secure a 35–31 victory.{{cite web |last1=Crouse |first1=Karen |title=As Manning and Other Stars Go to Work, Colts Go to 14-0 |url=https://www.nytimes.com/2009/12/18/sports/football/18colts.html |website=New York Times |access-date=29 August 2024 |archive-url=https://web.archive.org/web/20220617113805/https://www.nytimes.com/2009/12/18/sports/football/18colts.html |archive-date=June 17, 2022 |date=December 3, 2007}} The Colts extended their regular season winning streak to 23 games, an NFL record; however, the streak came to an end the following week with a defeat against the Jets.{{cite web |title=Colts bench key starters, lose unbeaten season to Jets, 29-15 |url=https://www.masslive.com/sports/2009/12/colts_lose_to_jets.html |website=MassLive |publisher=MassLive Media Group |access-date=23 July 2024 |archive-url=https://web.archive.org/web/20240723220153/https://www.masslive.com/sports/2009/12/colts_lose_to_jets.html |archive-date=July 23, 2024 |date=December 28, 2009}} Furthermore, the Colts accomplished a sweep of the AFC South for the second time in their history.{{cite web |last1=Bake |first1=Shake N' |title=Quick Recap: Colts 35, Jaguars 31 |url=https://www.stampedeblue.com/2009/12/17/1206795/quick-recap-colts-35-jaguars-31 |website=Stampede Blue |publisher=Vox Media |access-date=30 August 2024 |archive-url=https://web.archive.org/web/20100325233632/https://www.stampedeblue.com/2009/12/17/1206795/quick-recap-colts-35-jaguars-31 |archive-date=March 25, 2010 |date=December 17, 2009}}

The Jaguars ended the season with a losing streak and missed the playoffs. In the playoffs, the Colts went on to lose Super Bowl XLIV to the New Orleans Saints.{{cite web |last1=Spain |first1=Kevin |title=The New Orleans Saints win the Super Bowl |url=https://www.nola.com/sports/saints/the-new-orleans-saints-win-the-super-bowl/article_5e8a9558-2a0a-521d-b599-23d42d931f74.html |website=NOLA |publisher=Advance Publications |access-date=23 July 2024 |archive-url=https://web.archive.org/web/20240723221601/https://www.nola.com/sports/saints/the-new-orleans-saints-win-the-super-bowl/article_5e8a9558-2a0a-521d-b599-23d42d931f74.html |archive-date=July 23, 2024 |date=February 8, 2010}}

File:Josh Scobee.jpg has executed game-winning field goals against the Colts during their era of dominance. Notably, in a 2010 matchup, he kicked a game-winning 59–yard field goal against the Colts, establishing a record for the longest field goal made in Jaguars franchise history.]]

In the 2010 season on October 3 in Jacksonville, Josh Scobee kicked a game-winning 59–yard field goal, setting a record for the longest field goal made in Jaguars' franchise history and securing a 31–28 victory for them.

On December 19, the two teams faced off in Indianapolis with significant playoff stakes. The Jaguars held the top position in the AFC South with an 8–5 record, while the Colts were close behind at 7–6. A victory for the Jaguars would clinch their first-ever AFC South title, whereas a defeat for the Colts would effectively end their playoff hopes. In a departure from their previous encounters, the Colts excelled in their running game and effectively contained the Jaguars' offense. This helped them to a 34–24 victory, preventing the Jaguars from clinching the AFC South and allowing the Colts to dictate their playoff fate.{{cite web |last1=Ganguli |first1=Tania |title=Help Wanted: Jaguars lose control of postseason fate in loss to Colts |url=https://www.jacksonville.com/story/sports/nfl/2010/12/19/help-wanted-jaguars-lose-control-postseason-fate-loss-colts/15921095007/ |website=Jacksonville.com |access-date=4 September 2024 |archive-url=https://web.archive.org/web/20240904142522/https://www.jacksonville.com/story/sports/nfl/2010/12/19/help-wanted-jaguars-lose-control-postseason-fate-loss-colts/15921095007/ |archive-date=September 4, 2024 |date=December 19, 2010}} The Jaguars went on to lose their last two games, resulting in them missing the playoffs. Conversely, the Colts' resurgence enabled them to capture the AFC South title for the seventh time in eight seasons.{{cite web |title=Colts win AFC South |url=https://nypost.com/2011/01/03/colts-win-afc-south/ |website=New York Post |publisher=Sean Giancola |access-date=4 September 2024 |archive-url=https://web.archive.org/web/20240904152246/https://nypost.com/2011/01/03/colts-win-afc-south/ |archive-date=September 4, 2024 |date=January 3, 2011}}

This would turn out to be the last season Peyton Manning played for the Colts.{{cite web |title=Colts release Peyton Manning |url=https://www.espn.com/nfl/story/_/id/7656028/indianapolis-colts-peyton-manning-part-ways-14-seasons |website=ESPN |publisher=The Walt Disney Company |access-date=27 September 2024 |archive-url=https://web.archive.org/web/20160901225717/https://www.espn.com/nfl/story/_/id/7656028/indianapolis-colts-peyton-manning-part-ways-14-seasons |archive-date=September 1, 2016 |date=March 8, 2012}} Through the 19 games he played against the Jaguars as a Colts quarterback, he finished with a passer rating of 99.8 with 5,243 yards, 38 touchdowns and 13 interceptions,{{cite web |title=Peyton Manning vs Jaguars as a Colts in his career |url=https://www.statmuse.com/nfl/ask/peyton-manning-vs-jaguars-as-a-colts |website=Statmuse}} leading to a 14–5 record.{{cite web |title=Peyton Manning vs Jaguars record as a Colts in his career |url=https://www.statmuse.com/nfl/ask/peyton-manning-vs-jaguars-record-as-a-colts-in-his-career |website=Statmuse}} He was instrumental in the Colts' overall success during that period, particularly in their dominance over the Jaguars.{{cite web |last1=Shipley |first1=John |title=Peyton Manning's Dominance Over Jaguars is Still Unmatched Years Later |url=https://www.si.com/nfl/jaguars/news/years-later-peyton-mannings-dominance-over-jaguars-is-still-unmatched |website=SI |access-date=27 September 2024 |archive-url=https://web.archive.org/web/20200529204904/https://www.si.com/nfl/jaguars/news/years-later-peyton-mannings-dominance-over-jaguars-is-still-unmatched |archive-date=May 29, 2020 |date=May 21, 2020}}

Following Peyton Manning's neck surgery, he did not start in any games for the Colts in the 2011 NFL season.{{cite web |last1=Odonnell |first1=Wes |title=Peyton Manning: Colts Lose Again as QB Ruled out for Season |url=https://bleacherreport.com/articles/865838-peyton-manning-colts-lose-again-as-qb-ruled-out-for-season |website=Bleacher Report |publisher=Turner Sports |access-date=25 July 2024 |archive-url=https://web.archive.org/web/20110927122324/https://bleacherreport.com/articles/865838-peyton-manning-colts-lose-again-as-qb-ruled-out-for-season |archive-date=September 27, 2011 |date=September 26, 2011}} As a result, the team's highly ranked offense and defense from the prior season significantly declined.{{cite web |last1=Ganguli |first1=Tania |title=Colts: From dynasty to debacle |url=https://www.jacksonville.com/story/sports/nfl/2011/11/13/colts-dynasty-debacle/15884215007/ |website=Jacksonville.com |access-date=25 July 2024 |archive-url=https://web.archive.org/web/20240725163636/https://www.jacksonville.com/story/sports/nfl/2011/11/13/colts-dynasty-debacle/15884215007/ |archive-date=July 25, 2024 |date=November 12, 2011}} Despite the Jaguars' overall struggles, they beat the Colts twice to record their first season sweep of the Colts. Additionally, they became the first AFC South team since the 2002 Titans to accomplish a sweep of the Colts, and the only AFC South team that did not suffer a loss to the Colts that season.{{cite web |title=Maurice Jones-Drew locks up rushing title; Colts will pick first in April |url=https://www.espn.com/nfl/recap?gameId=320101030 |website=ESPN |publisher=The Walt Disney Company |access-date=3 September 2024 |archive-url=https://web.archive.org/web/20190617141706/https://www.espn.com/nfl/recap?gameId=320101030 |archive-date=June 17, 2019 |date=January 2, 2012}} The Colts' defeat to the Jaguars in their season finale positioned the Colts to secure the first overall pick in the 2012 NFL draft, leading them to select the highly regarded prospect Stanford QB Andrew Luck while parting ways with Peyton Manning.

File:Andrew Luck.JPG finished with a 7–3 record against the Jaguars and significantly contributed to the Colts success during the 2010s.|left]]

In the 2012 season, Andrew Luck made his debut against the Jaguars on September 23 in Indianapolis. He threw two touchdown passes, helping the Colts take a 14–3 lead at halftime. However, the Jaguars rallied in the fourth quarter. In the final minutes, Luck guided the Colts down the field for a field goal that put them back into the lead. Yet, the very first play of the next drive saw Jaguars' QB Blaine Gabbert connect with WR Cecil Shorts, who dashed 80 yards for a touchdown, ultimately leading the Jaguars to a 22–17 victory and spoiling Luck's debut in the rivalry.{{cite web |title=Gabbert's 80-yard pass to Shorts sends Jaguars past Colts |url=https://nypost.com/2012/09/23/gabberts-80-yard-pass-to-shorts-sends-jaguars-past-colts/ |website=New York Post |publisher=Sean Giancola |access-date=3 September 2024 |archive-url=https://web.archive.org/web/20240903182424/https://nypost.com/2012/09/23/gabberts-80-yard-pass-to-shorts-sends-jaguars-past-colts/ |archive-date=September 3, 2024 |date=September 23, 2012 |url-status=live}}

The game marked a turning point for the Colts, who subsequently enhanced their performance for the remainder of the season,{{cite web |title=Colts consider Jaguars' loss turning point |url=https://www.chicagotribune.com/2012/11/07/colts-consider-jaguars-loss-turning-point/ |website=Chicago Tribune |publisher=Tribune Publishing |access-date=5 September 2024 |archive-url=https://web.archive.org/web/20240905172215/https://www.chicagotribune.com/2012/11/07/colts-consider-jaguars-loss-turning-point/ |archive-date=September 5, 2024 |date=November 7, 2012}} ultimately securing the 5th seed{{cite web |title=2012 NFL Standings & Team Stats |url=https://www.pro-football-reference.com/years/2012/index.htm |website=Pro Football Reference |access-date=5 September 2024 |archive-url=https://web.archive.org/web/20130612095415/https://www.pro-football-reference.com/years/2012/index.htm |archive-date=June 12, 2013}} and avenging their earlier loss to the Jaguars.{{cite web |title=NFL: Colts 27, Jaguars 10: No letdown for Indianapolis: Colts cruise past Jacksonville |url=https://tucson.com/sports/football/article_24d4d3d9-2950-5439-8fd6-331ed5c38653.html |website=Tucson |access-date=5 September 2024 |archive-url=https://web.archive.org/web/20240905173010/https://tucson.com/sports/football/article_24d4d3d9-2950-5439-8fd6-331ed5c38653.html |archive-date=September 5, 2024 |date=November 9, 2012}} The Jaguars concluded their season with a disappointing 2–14 record, with their victory over the Colts being one of their few highlights.

In the 2013 season, the Colts recorded their biggest victory against the Jaguars on September 29 in Jacksonville. Although the Jaguars initially led 3–0 at the end of the first quarter, the Colts dominated the remainder of the game, winning 37–3. This marked their largest victory over the Jaguars, with a 34–point difference.{{cite web |title=Andrew Luck, sluggish Colts have more than enough vs. Jaguars |url=https://www.espn.com/nfl/recap?gameId=330929030 |website=ESPN |publisher=The Walt Disney Company |access-date=10 September 2024 |archive-url=https://web.archive.org/web/20240905181546/https://www.espn.com/nfl/recap?gameId=330929030 |archive-date=September 5, 2024 |date=September 29, 2013}}{{cite web |title=Colts biggest point differential in a game against the Jaguars |url=https://www.statmuse.com/nfl/ask?q=colts+biggest+point+differnetal+in+a+regular-season+game+against+the+jaguars |website=Statmuse}} The Colts won again over the Jaguars in their season finale to complete their third sweep of the AFC South.{{cite web |last1=Goff |first1=Chris |title=Hot Colts coast by Jaguars |url=https://www.chicagotribune.com/2013/12/30/hot-colts-coast-by-jaguars/ |website=Chicago Tribune |publisher=Tribune Publishing |access-date=10 September 2024 |archive-url=https://web.archive.org/web/20240910134005/https://www.chicagotribune.com/2013/12/30/hot-colts-coast-by-jaguars/ |archive-date=September 10, 2024 |date=December 30, 2013}}

The Colts continued their strong performance throughout the 2014 season. On September 21, they crushed the Jaguars 44–17 in Jacksonville, scoring their most points in a game against the Jaguars.{{cite web |title=Colts most points in a game against the Jaguars |url=https://www.statmuse.com/nfl/ask/colts-most-points-in-a-game-against-the-jaguars |website=Statmuse}} Andrew Luck had one of his best performances, completing 31–of–39 for 370 yards and four touchdowns.{{cite web |title=Colts Take Down Jaguars, 44-17 |url=https://ca.sports.yahoo.com/news/colts-down-jaguars-44-17-203926962--nfl.html |website=Yahoo |access-date=10 September 2024 |archive-url=https://web.archive.org/web/20240910150653/https://ca.sports.yahoo.com/news/colts-down-jaguars-44-17-203926962--nfl.html |archive-date=September 10, 2024 |date=September 21, 2014}} The Colts would go on to sweep their division again.{{cite web |last1=Bowen |first1=Kevin |title=2014 Colts Regular Season Capped With Another Division Sweep |url=https://www.colts.com/news/2014-colts-regular-season-capped-with-another-division-sweep-14675851 |website=Indianapolis Colts |access-date=27 September 2024 |archive-url=https://web.archive.org/web/20221208203228/https://www.colts.com/news/2014-colts-regular-season-capped-with-another-division-sweep-14675851 |archive-date=December 8, 2022 |date=December 28, 2014}}

Andrew Luck was unable to participate in his first NFL game due to a right shoulder injury in the 2015 season, as the Colts faced the Jaguars on October 4 in Indianapolis. In a low-scoring game, Jaguars K Jason Myers missed two game-winning field goals: a 53-yarder at the end of regulation and a 48-yarder in overtime. In response, Colts backup QB Matt Hasselbeck orchestrated a 53–yard drive that ended with K Adam Vinatieri successfully converting a game-winning 27-yard field goal, winning 16–13.{{cite web |title=Adam Vinatieri's field goals leads Colts past Jaguars in OT |url=https://www.espn.com/nfl/recap/_/gameId/400791671 |website=ESPN |publisher=The Walt Disney Company |access-date=10 September 2024 |archive-url=https://web.archive.org/web/20160902163559/https://www.espn.com/nfl/recap/_/gameId/400791671 |archive-date=September 2, 2016 |date=October 4, 2015}}

Jaguars recorded their biggest victory over the Colts on December 13 in Jacksonville, with Hasselbeck once again taking over for Luck. The game began slowly, with the Colts holding a 13–9 lead at halftime. However, the Jaguars surged in the second half, outscoring the Colts 42–3 and scoring on every possession, ultimately dominating the Colts to a 51–16 victory. This victory marked a franchise record for the Jaguars in terms of points scored in a regular season game, represented their largest victory over the Colts with a 35–point differential, ended a six-game losing streak against them, and snapped the Colts' 16-game winning streak in the AFC South, which stands as an NFL record in all divisional play.{{cite web |last1=Long |first1=Mark |title=Jaguars beat Colts 51-16, ending Indy's AFC South streak |url=https://apnews.com/article/de716c19650b492c87f7a9c6f58e7822 |website=Associated Press |access-date=11 September 2024 |archive-url=https://web.archive.org/web/20240911143644/https://apnews.com/article/de716c19650b492c87f7a9c6f58e7822 |archive-date=September 11, 2024 |date=December 13, 2015 |url-status=live}}{{cite web |title=Jaguars biggest point differential in a game against the Colts' |url=https://www.statmuse.com/nfl/ask?q=jaguars+biggest+point+differnetal+in+a+regular-season+game+against+the+colts |website=Statmuse}}

Instead of hosting a game in Jacksonville during the 2016 season, the NFL arranged for the Jaguars and Colts to compete at the Wembley Stadium in Wembley, London. This matchup was designated as a home game for Jacksonville as part of the league's international series.{{cite web |title=Jaguars to play Colts in London in 2016 |url=https://www.jaguars.com/news/jaguars-to-play-colts-in-london-in-2016-16369289 |website=Jacksonville Jaguars |access-date=11 September 2024 |archive-url=https://web.archive.org/web/20210512120409/https://www.jaguars.com/news/jaguars-to-play-colts-in-london-in-2016-16369289 |archive-date=May 12, 2021 |date=November 25, 2015}} In a crowd that evenly supported both teams, the Colts struggled with dropped passes and penalties, allowing the Jaguars to establish a 23–6 lead by the beginning of the fourth quarter. Although Luck and the Colts tried to mount a comeback, the Jaguars held on to a 30–27 victory.{{cite web |last1=Bandini |first1=Nicky |title=Wembley win finally gives Jacksonville Jaguars something to write home about |url=https://www.theguardian.com/sport/2016/oct/02/jacksonville-jaguars-indianapolis-colts-wembley |website=The Guardian |access-date=11 September 2024 |archive-url=https://web.archive.org/web/20161002185858/https://www.theguardian.com/sport/2016/oct/02/jacksonville-jaguars-indianapolis-colts-wembley |archive-date=October 2, 2016 |date=October 2, 2016}}{{cite web |title=Jaguars 30-27 Colts: NFL Wembley win for Jacksonville as Blake Bortles stars |url=https://www.bbc.com/sport/american-football/37532344 |website=BBC |access-date=11 September 2024 |archive-url=https://web.archive.org/web/20161003120616/https://www.bbc.com/sport/american-football/37532344 |archive-date=October 3, 2016 |date=October 2, 2016}}

Andrew Luck missed the 2017 season season due to shoulder surgery.{{cite web |last1=D'Andrea |first1=Christian |title=Andrew Luck headed to injured reserve, will not play in 2017 |url=https://www.sbnation.com/nfl/2017/11/2/16466114/2017-nfl-injury-andrew-luck-injured-reserve |website=SBNation |publisher=Vox Media |access-date=4 August 2024 |archive-url=https://web.archive.org/web/20171216174226/https://www.sbnation.com/nfl/2017/11/2/16466114/2017-nfl-injury-andrew-luck-injured-reserve |archive-date=December 16, 2017 |date=November 2, 2017 |url-status=live}} The Jaguars, initially expected to be one of the weakest teams,{{cite web |title=AFC South 2017 predictions: Time to take division, and the Titans, seriously |url=https://au.sports.yahoo.com/afc-south-2017-predictions-time-145808733.html |website=Yahoo |access-date=13 September 2024 |archive-url=https://web.archive.org/web/20240913155712/https://au.sports.yahoo.com/afc-south-2017-predictions-time-145808733.html |archive-date=September 13, 2024 |date=July 25, 2017}} have surprisingly started strong, thanks in large part to their defense, which was being nicknamed "Sacksonville".{{cite web |last1=Oehser |first1=John |title=Twenty-five seasons, twenty-five games: Jaguars 29, Texans 7 |url=https://www.jaguars.com/news/twenty-five-seasons-twenty-five-games-jaguars-29-texans-7 |website=Jacksonville Jaguars |access-date=13 September 2024 |archive-url=https://web.archive.org/web/20201108012914/https://www.jaguars.com/news/twenty-five-seasons-twenty-five-games-jaguars-29-texans-7 |archive-date=November 8, 2020 |date=July 15, 2019}} When the Jaguars faced the Colts on October 22 in Indianapolis, their defense dominated, sacking backup QB Jacoby Brissett 10 times, equaling the franchise's single-game record set in their season-opener against the Texans, and securing a 27–0 shutout victory.{{cite web |title=Bortles, Jaguars' D sacks Colts 27-0 to stay atop division |url=https://www.espn.com/nfl/recap/_/gameId/400951589 |website=ESPN |publisher=The Walt Disney Company |access-date=13 September 2024 |archive-url=https://web.archive.org/web/20171027022905/https://www.espn.com/nfl/recap/_/gameId/400951589 |archive-date=October 27, 2017 |date=October 22, 2017}} This performance tied the Colts for the second-most sacks allowed in a single game.{{cite web |last1=Chappell |first1=Mike |title=Jacksonville introduces Colts to Rock Bottom, USA |url=https://fox59.com/sports/colts/jacksonville-introduces-colts-to-rock-bottom-usa/ |website=Fox 59 |access-date=13 September 2024 |archive-url=https://web.archive.org/web/20240913172805/https://fox59.com/sports/colts/jacksonville-introduces-colts-to-rock-bottom-usa/ |archive-date=September 13, 2024 |date=October 22, 2017}} The Jaguars achieved their first shutout since a 41–0 win over the Jets in the 2006 season, while the Colts experienced their first shutout since the 2002 playoffs, where they lost 41–0 to the Jets, and their first regular-season shutout since 1993.{{cite web |title=Colts search for answers after disheartening shutout loss |url=https://www.foxsports.com/stories/other/colts-search-for-answers-after-disheartening-shutout-loss |website=Fox Sports |access-date=27 September 2024 |archive-url=https://web.archive.org/web/20240927154927/https://www.foxsports.com/stories/other/colts-search-for-answers-after-disheartening-shutout-loss |archive-date=September 27, 2024 |date=October 22, 2017}} Additionally, the Jaguars amassed 518 total yards, ranking as the third highest in franchise history.{{cite web |title=Jaguars most yards in a game |url=https://www.statmuse.com/nfl/ask/jaguars-most-yards-in-a-game |website=Statmuse}} Following the game, the Jaguars' Twitter account (now referred to as X) updated its name to "Sacksonville" to fully embrace the moment.{{cite web |last1=Crawford |first1=Dakota |title=Watch all 10 sacks that prompted the Jaguars to change their Twitter name |url=https://www.indystar.com/story/sports/nfl/colts/2017/10/22/jaguars-troll-colts-twitter-name-change-after-racking-up-10-sacks/788955001/ |website=IndyStar |publisher=Gannett |access-date=27 September 2024 |archive-url=https://web.archive.org/web/20201203173210/https://www.indystar.com/story/sports/nfl/colts/2017/10/22/jaguars-troll-colts-twitter-name-change-after-racking-up-10-sacks/788955001/ |archive-date=December 3, 2020 |date=October 22, 2017}}

Before their second matchup on December 3 in Jacksonville, the Jacksonville International Airport displayed signs celebrating the Jaguars' victory over the Colts in their earlier meeting.{{cite web |last1=VanTryon |first1=Matthew |title=Colts get trolled by Jacksonville airport |url=https://www.indystar.com/story/sports/nfl/colts/2017/12/02/colts-get-trolled-jacksonville-airport/916483001/ |website=IndyStar |publisher=Gannett |access-date=27 September 2024 |archive-url=https://web.archive.org/web/20200930190221/https://www.indystar.com/story/sports/nfl/colts/2017/12/02/colts-get-trolled-jacksonville-airport/916483001/ |archive-date=September 30, 2020 |date=December 2, 2017}} The Jaguars dominated the Colts again that marked their second sweep of the team since the inception of the AFC South.{{cite web |last1=Kouvaris |first1=Sam |title=Sam: Jaguars sweep Colts, eye postseason |url=https://www.news4jax.com/sports/2017/12/03/sam-jaguars-sweep-colts-eye-postseason/ |website=News4Jax |access-date=14 September 2024 |archive-url=https://web.archive.org/web/20210304073114/https://www.news4jax.com/sports/2017/12/03/sam-jaguars-sweep-colts-eye-postseason/ |archive-date=March 4, 2021 |date=December 3, 2017}} During the game, DT Calais Campbell established a new single-season sack record for the Jaguars.{{cite web |last1=Day |first1=Ryan |title=Calais Campbell sets new Jaguars single-season franchise record for sacks |url=https://www.bigcatcountry.com/2017/12/3/16730730/calais-campbell-sets-new-jaguars-single-season-franchise-record-for-sacks |website=Big Cat Country |publisher=Vox Media |access-date=14 September 2024 |archive-url=https://web.archive.org/web/20171222233639/https://www.bigcatcountry.com/2017/12/3/16730730/calais-campbell-sets-new-jaguars-single-season-franchise-record-for-sacks |archive-date=December 22, 2017 |date=December 3, 2017}} This sweep of the Colts ultimately played a crucial role in the Jaguars achieving their first AFC South title.{{cite web |title=Jaguars clinch AFC South with Titans' loss |url=https://www.jacksonville.com/story/sports/2017/12/24/jaguars-clinch-afc-south-titans-loss/15782951007/ |website=Jacksonville.com |publisher=Morris Communications |access-date=14 September 2024 |archive-url=https://web.archive.org/web/20240914135414/https://www.jacksonville.com/story/sports/2017/12/24/jaguars-clinch-afc-south-titans-loss/15782951007/ |archive-date=September 14, 2024 |date=December 24, 2017 |url-status=live}}

Luck returned in the 2018 season when the Colts faced the Jaguars on November 11 in Indianapolis. The Jaguars, a popular preseason pick, had a rocky start to the season, entering the game with a 3–5 record.{{cite web |last1=Heilman |first1=Phillip |title='Utterly unexplainable': Jaguars' slide continues with loss to Indianapolis Colts |url=https://www.jacksonville.com/story/sports/nfl/2018/11/12/utterly-unexplainable-jaguars-slide-continues-with-loss-to-indianapolis-colts/7961430007/ |website=Jacksonville.com |publisher=Morris Communications |access-date=14 September 2024 |archive-url=https://web.archive.org/web/20240914160214/https://www.jacksonville.com/story/sports/nfl/2018/11/12/utterly-unexplainable-jaguars-slide-continues-with-loss-to-indianapolis-colts/7961430007/ |archive-date=September 14, 2024 |date=November 11, 2018}} The Colts scored 29 points in the first half, which ultimately proved to be enough. The Jaguars attempted a rally and were approaching Indianapolis territory to tie the game, but a fumble by WR Rashad Greene ultimately secured a 29–26 victory for the Colts. Luck completed 21–of–29 passes for 285 yards and threw three touchdown passes.{{cite web |title=Luck, Ebron lead Colts past struggling Jaguars 29-26 |url=https://www.cbssports.com/nfl/gametracker/recap/NFL_20181111_JAC@IND/ |website=CBSSports |access-date=14 September 2024 |archive-url=https://web.archive.org/web/20181113085726/https://www.cbssports.com/nfl/gametracker/recap/NFL_20181111_JAC@IND/ |archive-date=November 13, 2018 |date=November 11, 2018}}

Although both teams were heading in vastly different directions, the Jaguars achieved one of their biggest defensive wins against the Colts on December 2 in Jacksonville. In a match devoid of touchdowns from either team, the Jaguars defeated the Colts 6–0. The Colts, who entered the game ranked fourth in the league for scoring, passed on two field-goal attempts in the first half, including one initially successful but later nullified. They finished going 5–18 on third downs and 0–3 on fourth downs, all within field-goal range. This win ended the Jaguars seven-game losing streak and the Colts five-game winning streak.{{cite web |title=Jaguars show up on defense, shut down Luck, Colts 6-0 |url=https://www.espn.com/nfl/recap/_/gameId/401030962 |website=ESPN |publisher=The Walt Disney Company |access-date=28 September 2024 |archive-url=https://web.archive.org/web/20240918133339/https://www.espn.com/nfl/recap/_/gameId/401030962 |archive-date=September 18, 2024 |date=December 2, 2018}} Following a 1–5 start, the Colts went 9–1 the rest of the season to finish at 10–6, with this loss to Jacksonville being their only loss during that stretch.{{cite web |title=2018 Indianapolis Colts Game Log |url=https://www.pro-football-reference.com/teams/clt/2018/gamelog/ |website=Pro Football Reference |archive-url=https://web.archive.org/web/20201123163227/https://www.pro-football-reference.com/teams/clt/2018/gamelog/ |archive-date=November 23, 2020 |url-status=live}}

This would be the last time Luck took the field as a starter in this series, as he unexpectedly announced his retirement in the subsequent offseason.{{cite web |last1=Ayello |first1=Jim |title=Insider: Andrew Luck retired. It really happened. So what's next for the Colts? |url=https://www.indystar.com/story/sports/nfl/colts/2019/08/25/andrew-luck-retired-really-happened-so-whats-next-colts/2051574001/ |website=IndyStar |publisher=Gannett |access-date=5 August 2024 |archive-url=https://web.archive.org/web/20190825074731/https://www.indystar.com/story/sports/nfl/colts/2019/08/25/andrew-luck-retired-really-happened-so-whats-next-colts/2051574001/ |archive-date=August 25, 2019 |date=August 25, 2019 |url-status=live}} Throughout 10 games against the Jaguars, Luck recorded a 93.9 passer rating, accumulating 2,790 yards, 17 touchdowns, and 7 interceptions,{{cite web |title=Andrew Luck stats vs Jaguars in his career |url=https://www.statmuse.com/nfl/ask/andrew-luckstats-vs-jaguars |website=Statmuse}} leading to a 7–3 record.{{cite web |title=Andrew Luck record vs Jaguars in his career |url=https://www.statmuse.com/nfl/ask/andrew-luck-record-vs-jaguars |website=Statmuse}} His contributions were pivotal in shifting the rivalry in favor of the Colts and enhancing their overall success.{{cite web |title=Gene Frenette: Andrew Luck proves he's elite; bad news for Jags |url=https://www.jacksonville.com/story/news/2015/01/13/gene-frenette-andrew-luck-proves-hes-elite-bad-news/15646879007/ |website=Jacksonville.com |publisher=Morris Communications |access-date=18 September 2024 |archive-url=https://web.archive.org/web/20230331060423/https://www.jacksonville.com/story/news/2015/01/13/gene-frenette-andrew-luck-proves-hes-elite-bad-news/15646879007/ |archive-date=March 31, 2023 |date=January 13, 2015}}{{cite web |last1=Bowen |first1=Kevin |title=Colts Dominate Jaguars In 44-17 Win |url=https://www.colts.com/news/colts-dominate-jaguars-in-44-17-win-13812921 |website=Indianapolis Colts |access-date=18 September 2024 |archive-url=https://web.archive.org/web/20220926115235/https://www.colts.com/news/colts-dominate-jaguars-in-44-17-win-13812921 |archive-date=September 26, 2022 |date=September 21, 2014}}

File:Gardner Minshew.png opener against the Colts, Jaguars quarterback Gardner Minshew completed 19–of–20 for 173 yards and three touchdowns, guiding the Jaguars to their only win in the 2020 season. Minshew would later start for the Colts in the 2023 season following a season-ending injury to QB Anthony Richardson.]]

After trading away many of their key players, the Jaguars were expected to rank among the weakest teams in the NFL in the 2020 season. In the season opener on September 13 in Jacksonville, the Colts were favored by 8 points over the Jaguars. In the game, the Colts didn't punt once, allowed no sacks of QB Philip Rivers, outgained the Jaguars 445–241 in total yardage and won the time-of-possession battle 33:23 to 26:37. Despite these advantages, missed opportunities, two interceptions by Rivers that led to 10 Jaguars points, and the Colts' defense allowing Jaguars QB Gardner Minshew to complete 19–of–20 for 173 yards, three touchdowns, and no interceptions resulted in a shocking 27–20 victory for the Jaguars.{{cite web |last1=Oehser |first1=John |title=Game report: Jaguars 27, Colts 20 |url=https://www.jaguars.com/news/game-report-jaguars-27-colts-20 |website=Jacksonville Jaguars |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20200914115751/https://www.jaguars.com/news/game-report-jaguars-27-colts-20 |archive-date=September 14, 2020 |date=September 13, 2020}}{{cite web |last1=Kravitz |first1=Bob |title=Kravitz: Philip Rivers' miscues in crunch time sink Colts in loss to Jaguars |url=https://www.nytimes.com/athletic/2063924/2020/09/13/kravitz-philip-rivers-miscues-in-crunch-time-sink-colts-in-loss-to-jaguars/ |website=The Athletic |publisher=The New York Times Company |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20240918202302/https://www.nytimes.com/athletic/2063924/2020/09/13/kravitz-philip-rivers-miscues-in-crunch-time-sink-colts-in-loss-to-jaguars/ |archive-date=September 18, 2024 |date=September 13, 2020}} This victory would ultimately be the Jaguars' only win in their 2020 season.{{cite web |title=2020 Jacksonville Jaguars Rosters, Stats, Schedule, Team Draftees, Injury Reports |url=https://www.pro-football-reference.com/teams/jax/2020.htm |website=Pro Football Reference |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20210118222642/https://www.pro-football-reference.com/teams/jax/2020.htm |archive-date=January 18, 2021}}

As the season finale approached on January 3 in Indianapolis, the Colts found themselves in a good playoff position following the Dolphins' loss to the Bills. The Colts needed a win to secure a playoff berth against the struggling Jaguars, who were enduring a 15–game losing streak, having not won since their initial victory over the Colts in week 1. Despite the game once again being tightly contested, the Jaguars ultimately allowed Colts' rookie RB Jonathan Taylor to set a franchise record by rushing for 253 yards and make a pivotal 45–yard touchdown run to the end zone with 3:35 remaining, leading the Colts to a 28–14 win.{{cite web |title=Taylor-made day sends Colts past Jags, back into playoffs |url=https://www.thescore.com/nfl/events/33449/RECAP |website=The Score |access-date=18 September 2024 |date=January 3, 2021}} The Colts clinched the 7th seed in the AFC, making them the first AFC 7th seed as the playoff format was expanded in the offseason.{{cite web |last1=Hickey |first1=Kevin |title=Colts sneak into playoffs as No. 7 seed |url=https://coltswire.usatoday.com/2021/01/03/indianapolis-colts-playoffs-7th-seed/ |website=ColtsWire |access-date=18 September 2024 |archive-url=https://web.archive.org/web/20210124191417/https://coltswire.usatoday.com/2021/01/03/indianapolis-colts-playoffs-7th-seed/ |archive-date=January 24, 2021 |date=January 3, 2021}} Conversely, the Jaguars concluded the season with a dismal 1–15 record, the worst in franchise history, with their sole win being against the Colts. However, they had the first overall pick in the 2021 NFL draft, which they used to select Clemson QB Trevor Lawrence.{{cite web |last1=Reid |first1=John |title=Jacksonville Jaguars select Clemson quarterback Trevor Lawrence with No. 1 overall pick |url=https://www.jacksonville.com/story/sports/nfl/2021/04/29/trevor-lawrence-jacksonville-jaguars-first-pick-nfl-draft/4874882001/ |website=Jacksonville.com |publisher=Morris Communications |access-date=18 September 2024 |archive-url=https://web.archive.org/web/20210430005909/https://www.jacksonville.com/story/sports/nfl/2021/04/29/trevor-lawrence-jacksonville-jaguars-first-pick-nfl-draft/4874882001/ |archive-date=April 30, 2021 |date=April 29, 2021}}

In the 2021 season finale, the Colts once again found themselves in a favorable playoff position as they faced the Jaguars on January 9 in Jacksonville. Although they had lost the AFC South title to the Titans the week prior,{{cite web |last1=Chiari |first1=Mike |title=Titans Clinch AFC South Title, 2022 NFL Playoff Berth After Colts' Loss to Raiders |url=https://bleacherreport.com/articles/10021207-titans-clinch-afc-south-title-2022-nfl-playoff-berth-after-colts-loss-to-raiders |website=Bleacher Report |publisher=Turner Sports |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220103002448/https://bleacherreport.com/articles/10021207-titans-clinch-afc-south-title-2022-nfl-playoff-berth-after-colts-loss-to-raiders |archive-date=January 3, 2022 |date=January 2, 2022}} a victory against the struggling 2–14 Jaguars, who were on an eight-game losing streak, would clinch a playoff berth for the Colts.{{cite web |last1=Stankevitz |first1=JJ |title=2021 Week 18 NFL Playoff Picture: Colts Clinching, Seeding Scenarios |url=https://www.colts.com/news/nfl-playoffs-scenarios-clinching-seeding-afc-week-18-chargers-raiders |website=Indianapolis Colts |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220104153827/https://www.colts.com/news/nfl-playoffs-scenarios-clinching-seeding-afc-week-18-chargers-raiders |archive-date=January 4, 2022 |date=January 4, 2022}} The matchup, referred to as the "Clown game" due to some Jaguars fans donning clown costumes in protest of owner Shad Khan's decision to retain general manager Trent Baalke,{{cite web |last1=Rorabaugh |first1=Dan |title=No joke! Jacksonville Jaguars fans dress up as clowns to protest owner Shad Khan, GM Trent Baalke |url=https://www.jacksonville.com/story/sports/nfl/2022/01/09/jaguars-clown-game-jacksonville-fans-shad-khan-colts/9125671002/ |website=Jacksonville.com |publisher=Morris Communications |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220109231413/https://www.jacksonville.com/story/sports/nfl/2022/01/09/jaguars-clown-game-jacksonville-fans-shad-khan-colts/9125671002/ |archive-date=January 9, 2022 |date=January 9, 2022}} ended in a surprising upset as the Jaguars defeated the Colts 26–11.{{cite web |title=Jaguars clown Colts 26-11, prevent Indy from making playoffs |url=https://www.espn.com/nfl/recap/_/gameId/401326591 |website=ESPN |publisher=The Walt Disney Company |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220110190253/https://www.espn.com/nfl/recap/_/gameId/401326591 |archive-date=January 10, 2022 |date=January 9, 2022}} The Jaguars established an early lead that they maintained throughout the game, led by Trevor Lawrence completing 23–of–32 for 223 yards, two touchdowns, and no interceptions, his first game with multiple TD passes since the season opener.{{cite web |last1=Oehser |first1=John |last2=Sexton |first2=Brian |last3=Sullivan |first3=Ashlyn |title=Quick thoughts: Jaguars 26, Colts 11 |url=https://www.jaguars.com/news/quick-thoughts-jaguars-26-colts-11 |website=Jacksonville Jaguars |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220110002137/https://www.jaguars.com/news/quick-thoughts-jaguars-26-colts-11 |archive-date=January 10, 2022 |date=January 9, 2022}} The Jaguars' defense, which had allowed 50 points to the Patriots the week prior,{{cite web |title=Mac Jones, Patriots Drop 50 Points In Blowout Win Over Jaguars |url=https://www.cbsnews.com/boston/news/mac-jones-patriots-drop-50-points-in-blowout-win-over-jaguars/ |website=CBSnews |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220813061432/https://www.cbsnews.com/boston/news/mac-jones-patriots-drop-50-points-in-blowout-win-over-jaguars/ |archive-date=August 13, 2022 |date=January 2, 2022}} limited Jonathan Taylor, the NFL's leading rusher, to 77 yards on 15 carries and stopped him on fourth down twice. Additionally, they restricted Colts QB Carson Wentz to 17–of–29 for 185 yards and no touchdowns, while sacking him six times and forcing two turnovers.{{cite web |last1=Oehser |first1=John |title=Game report: Jaguars 26, Colts 11 |url=https://www.jaguars.com/news/game-report-jaguars-26-colts-11 |website=Jacksonville Jaguars |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220109215329/https://www.jaguars.com/news/game-report-jaguars-26-colts-11 |archive-date=January 9, 2022 |date=January 9, 2022}} This victory not only ended the Jaguars' eight-game losing streak but also eliminated the Colts from playoff contention following the Steelers' win over the Ravens.{{cite web |last1=Bergman |first1=Jeremy |title=Colts eliminated from playoff contention following shocking loss to Jaguars |url=https://www.nfl.com/news/colts-eliminated-from-playoff-contention-following-shocking-loss-to-jaguars |website=NFL.com |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220109225228/https://www.nfl.com/news/colts-eliminated-from-playoff-contention-following-shocking-loss-to-jaguars |archive-date=January 9, 2022 |date=January 9, 2022}}

The embarrassments continued for the Colts in the 2022 season, suffering a 24–0 shutout loss to the Jaguars on September 18 in Jacksonville. This defeat marked the third occasion in the last six seasons that the Colts were shutout by the Jaguars.{{Cite web |date=September 18, 2022 |title=Jags' home win streak vs Colts reaches 8 with 24-0 shutout |url=https://www.espn.com/nfl/recap/_/gameId/401437639 |url-status=live |archive-url=https://web.archive.org/web/20220930054854/https://www.espn.com/nfl/recap/_/gameId/401437639 |archive-date=September 30, 2022 |access-date=20 September 2024 |website=ESPN.com|agency=Associated Press |publisher=The Walt Disney Company}} Additionally, it was the Jaguars' first shutout since the 2018 season, which was also against the Colts.{{cite web |last1=Barney |first1=Justin |title=Finally! Best performance in years delivers Jaguars dominant win over Colts |url=https://www.news4jax.com/sports/2022/09/18/finally-best-performance-in-years-delivers-jaguars-dominant-win-over-colts/ |website=News4Jax |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220918195113/https://www.news4jax.com/sports/2022/09/18/finally-best-performance-in-years-delivers-jaguars-dominant-win-over-colts/ |archive-date=September 18, 2022 |date=September 18, 2022}}

The Colts managed to secure a measure of revenge when QB Matt Ryan delivered a game-winning 32–yard touchdown pass with just 17 seconds remaining on October 16 in Indianapolis, leading the team to a 34–27 victory.{{cite web |last1=Marot |first1=Michael |title=Ryan, Pierce hook up in final minute, Colts beat Jags 34-27 |url=https://apnews.com/article/indianapolis-colts-jacksonville-jaguars-nfl-sports-59b3db7c528137884146d9d6994fbc60 |website=APnews |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20221017075319/https://apnews.com/article/indianapolis-colts-jacksonville-jaguars-nfl-sports-59b3db7c528137884146d9d6994fbc60 |archive-date=October 17, 2022 |date=October 16, 2022}}

Despite pre-season predictions that favored the Colts to win the AFC South and projected the Jaguars to finish near the bottom of the division,{{cite web |last1=Orr |first1=Conor |title=AFC South Preview and Predictions: Henry's Titans Look to Stay Ahead of Indy |url=https://www.si.com/nfl/2022/09/01/afc-south-predictions-projected-records |website=SI |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20220901133959/https://www.si.com/nfl/2022/09/01/afc-south-predictions-projected-records |archive-date=September 1, 2022 |date=September 1, 2022}}{{cite web |last1=Mock |first1=Austin |title=AFC South Projections: Colts the favorite over the Titans |url=https://www.nytimes.com/athletic/3513546/2022/08/17/afc-south-projections-2022-season/ |website=The Athletic |publisher=The New York Times Company |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20240920164330/https://www.nytimes.com/athletic/3513546/2022/08/17/afc-south-projections-2022-season/ |archive-date=September 20, 2024 |date=August 17, 2022}} the Jaguars ultimately claimed the AFC South championship while the Colts ended the season with a 4–12–1 record.{{cite web |title=2022 NFL Division Standings |url=https://www.nfl.com/standings/division/2022/reg |website=NFL.com |access-date=20 September 2024 |archive-url=https://web.archive.org/web/20230131083827/https://www.nfl.com/standings/division/2022/reg |archive-date=January 31, 2023}}

The 2023 season showcased the first matchup between Trevor Lawrence and QB Anthony Richardson, the latter being selected by the Colts in the 2023 NFL draft.{{cite web |last1=Patra |first1=Kevin |title=Colts select Florida QB Anthony Richardson with No. 4 overall pick in 2023 NFL Draft |url=https://www.nfl.com/news/colts-select-florida-qb-anthony-richardson-with-no-4-overall-pick-in-2023-nfl-dr |website=NFL.com |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20230429173030/https://www.nfl.com/news/colts-select-florida-qb-anthony-richardson-with-no-4-overall-pick-in-2023-nfl-dr |archive-date=April 29, 2023 |date=April 27, 2023}} This closely fought contest took place on September 10 in Indianapolis, where the Jaguars emerged victorious with a score of 31–21.{{cite web |last1=Harvey |first1=Demetrius |title=Jaguars overcome miscues to defeat Colts 31-21 in Week 1. Here are our takeaways. |url=https://www.jacksonville.com/story/sports/nfl/2023/09/10/jaguars-defeat-colts-31-21-in-week-1-ridley-scores-touchdown-takeaways/70761445007/ |website=Jacksonville.com |publisher=Morris Communications |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20240312095513/https://www.jacksonville.com/story/sports/nfl/2023/09/10/jaguars-defeat-colts-31-21-in-week-1-ridley-scores-touchdown-takeaways/70761445007/ |archive-date=March 12, 2024 |date=September 10, 2023}}

In their second encounter on October 15 in Jacksonville, Richardson did not take the field as the starter; instead, former Jaguars quarterback Gardner Minshew led the Colts. The Jaguars' defense capitalized on Minshew's performance, forcing him into four turnovers, resulting in a 37–20 victory for the Jaguars and completing a season sweep of the Colts.{{cite web |title=Jaguars take advantage of Colts' mistakes to sweep season series |url=https://www.reuters.com/sports/nfl/jaguars-take-advantage-colts-mistakes-sweep-season-series-2023-10-15/ |website=Reuters |access-date=21 September 2024 |archive-url=https://web.archive.org/web/20240921143339/https://www.reuters.com/sports/nfl/jaguars-take-advantage-colts-mistakes-sweep-season-series-2023-10-15/ |archive-date=September 21, 2024 |date=October 15, 2023 |url-status=live}}

Both teams ultimately concluded the season with 9–8 records, but neither managed to qualify for the playoffs.{{cite web |title=2023 NFL Standings & Team Stats |url=https://www.pro-football-reference.com/years/2023/index.htm |website=Pro Football Reference |archive-url=https://web.archive.org/web/20240110142403/https://www.pro-football-reference.com/years/2023/index.htm |archive-date=January 10, 2024}}

{{Game log start|style={{NFLPrimaryStyle}};|title= Indianapolis Colts vs. Jacksonville Jaguars Season-by-Season Results}}

{{Game log section start|hide=y|style={{NFLPrimaryStyle|Indianapolis Colts}};|title=1990s–2000s (Colts, 14–4)|Season|{{nowrap|Season series}}|at Indianapolis Colts |at Jacksonville Jaguars|{{nowrap|Overall series}}|Notes}}

|-

| {{nfly|1995}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| {{nowrap|Colts 1–0}}

| {{N/A}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
41–31

| Colts
1–0

| Jaguars join the National Football League (NFL) as an expansion team. They are placed in the American Football Conference (AFC) and the AFC Central.

|-

|-

| {{nfly|2000}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| {{nowrap|Colts 1–0}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
43–14

| {{N/A}}

| Colts
2–0

|

|-

| {{nfly|2002}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| {{nowrap|Colts 2–0}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
20–13

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
28–25

| Colts
4–0

| During the NFL realignment, both teams are placed in the newly formed AFC South, resulting in two meetings annually.
In Indianapolis, the Colts clinch a playoff berth with their win.

|-

| {{nfly|2003}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
23–13

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
28–23

| Colts
5–1

|

|-

| {{nfly|2004}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
27–24

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
24–17

| Colts
6–2

| Colts' loss to the Broncos eliminated the Jaguars from playoff contention, preventing a wild-card matchup between the two teams.

|-

| {{nfly|2005}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| {{nowrap|Colts 2–0}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
10–3

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
26–18

| Colts
8–2

| In Jacksonville, Colts clinched the AFC South, the AFC's 1st seed, and achieved a sweep of the AFC South for the first time with their win.

|-

| {{nfly|2006}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
21–14

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
44–17

| Colts
9–3

| In Jacksonville, Jaguars finish with 375 rushing yards, setting a franchise record for their most rushing yards in a game. Meanwhile, the Colts set a franchise record for their most rushing yards allowed in a game.
Colts win Super Bowl XLI.

|-

| {{nfly|2007}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| {{nowrap|Colts 2–0}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
28–25

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
29–7

| Colts
11–3

| Last matchup at RCA Dome.

|-

| {{nfly|2008}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
23–21

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
31–24

| Colts
12–4

| Colts open Lucas Oil Stadium.
Colts clinch a playoff berth with their win.

|-

| {{nfly|2009}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| {{nowrap|Colts 2–0}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
14–12

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
35–31

| Colts
14–4

| In Jacksonville, Colts extend their regular season game–winning streak to 23, an NFL record, and swept the AFC South for a second time with their win.

|-

{{Game log section end}}

{{Game log section start|hide=y|style={{NFLPrimaryStyle}};|title=2010s (Tie, 10–10)|Season|{{nowrap|Season series}}|at Indianapolis Colts |at Jacksonville Jaguars|{{nowrap|Overall series}}|Notes}}

|-

| {{nfly|2010}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
34–24

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
31–28

| Colts
15–5

| Last start in the series for Colts' QB Peyton Manning.
In Jacksonville, Jaguars' K Josh Scobee kicked a game-winning 59-yard field goal, setting a franchise record for their longest field goal made.
Colts' win prevented the Jaguars from clinching their first AFC South title.

|-

| {{nfly|2011}}

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| {{nowrap|Jaguars 2–0}}

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
17–3

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
19–13

| Colts
15–7

| Jaguars record their first season series sweep over the Colts.
Colts clinch the first overall pick in the 2012 NFL draft with their loss in Jacksonville.

|-

| {{nfly|2012}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
22–17

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
27–10

| Colts
16–8

| Colts draft QB Andrew Luck.

|-

| {{nfly|2013}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| {{nowrap|Colts 2–0}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
30–10

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
37–3

| Colts
18–8

| In Jacksonville, Colts record their largest victory over the Jaguars with a 34–point differential.
In Indianapolis, Colts sweep the AFC South division with their win.

|-

| {{nfly|2014}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| {{nowrap|Colts 2–0}}

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
23–3

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
44–17

| Colts
20–8

| In Jacksonville, Colts score their most points in a game against the Jaguars.
Colts sweep the AFC South division for a second consecutive year.
As of {{date|2=MDY}}, this remains the Colts' most recent season series sweep against the Jaguars.

|-

| {{nfly|2015}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
16–13(OT)

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
51–16

| Colts
21–9

| First overtime result between the two teams.
In Jacksonville, Jaguars record their largest victory over the Colts with a 35–point differential, set a franchise record for their most points scored in a regular season game, and ended the Colts' 16–game winning streak against division opponents, an NFL record.

|-

| {{nfly|2016}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
24–20

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
30–27

| Colts
22–10

| Jaguars home game was played at Wembley Stadium in Wembley, London as part of the NFL International Series.
In Indianapolis, Colts overcome a 17–0 deficit.

|-

| {{nfly|2017}}

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| {{nowrap|Jaguars 2–0}}

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
27–0

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
30–10

| Colts
22–12

| In Indianapolis, Jaguars recorded 10 sacks, tying a franchise record.
In Jacksonville, Jaguars' DE Calais Campbell became the new single-season sack leader for the Jaguars (broken by DE Josh Hines-Allen in 2023).

|-

| {{nfly|2018}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
29–26

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
6–0

| Colts
23–13

| Final season for Andrew Luck.

|-

| {{nfly|2019}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
33–13

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
38–20

| Colts
24–14

|

|-

{{Game log section end}}

{{Game log section start|hide=y|style={{NFLPrimaryStyle|Jacksonville Jaguars}};|title=2020s (Jaguars, 6–4)|Season|{{nowrap|Season series}}|at Indianapolis Colts |at Jacksonville Jaguars|{{nowrap|Overall series}}|Notes}}

|-

| {{nfly|2020}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
28–14

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
27–20

| Colts
25–15

| Following their win, the Jaguars went on a 20-game losing streak. Jaguars' win was their only win in their 2020 season.
Colts clinch the final playoff spot with their win.

|-

| {{nfly|2021}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
23–17

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
26–11

| Colts
26–16

| Jaguars' win eliminated the Colts from playoff contention.

|-

| {{nfly|2022}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
34–27

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
24–0

| Colts
27–17

|

|-

| {{nfly|2023}}

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| {{nowrap|Jaguars 2–0}}

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
31–21

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
37–20

| Colts
27–19

|

|-

| {{nfly|2024}}

| Tie 1–1

| style="{{NFLPrimaryStyle|Indianapolis Colts}}| Colts
26–23(OT)

| style="{{NFLPrimaryStyle|Jacksonville Jaguars}}| Jaguars
37–34

| Colts
28–20

| Jaguars win ten straight home meetings (2015–present).

{{Game log section end}}

{{Game log section start|hide=y|style={{NFLPrimaryStyle}};|title=Summary of Results|Season|Season series|at Indianapolis Colts|at Jacksonville Jaguars|Notes}}

|-

| Regular season

| style="{{NFLPrimaryStyle|Indianapolis Colts}}|Colts 28–20

| Colts 18–6

| Jaguars 14–10

| Jaguars are 1–0 at Wembley Stadium in Wembley, London (2016), which was a Jaguars' home game.

|-

{{Game log section end}}

{{Game log end}}

• National Football League rivalries
• AFC South

{{reflist}}

{{Indianapolis Colts}}

{{Jacksonville Jaguars}}

{{NFL rivalries}}

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Category:NFL rivalries

Category:Indianapolis Colts rivalries

Category:Jacksonville Jaguars rivalries