Cyano-2 RNA motif

{{primary sources|date=November 2021}}

{{Infobox rfam

| Name = Cyano-2 RNA motif

| image = Cyano-2-RNA.svg

| width = 350

| caption = Consensus secondary structure of Cyano-2 RNAs

| Symbol = Cyano-2

| AltSymbols =

| Rfam = RF01702

| miRBase =

| miRBase_family =

| RNA_type = sRNA

| Tax_domain = Synechococcus

| GO =

| SO =

}}

The Cyano-2 RNA motif is a conserved RNA structure identified by bioinformatics.{{cite journal |vauthors=Weinberg Z, Wang JX, Bogue J |title=Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes |journal=Genome Biol |volume=11 |issue=3 |pages=R31 |date=March 2010 |pmid=20230605 |doi=10.1186/gb-2010-11-3-r31 |pmc=2864571|display-authors=etal |doi-access=free }} Cyano-2 RNAs are found in Cyanobacterial species classified within the genus Synechococcus. Many terminal loops in the two conserved stem-loops contain the nucleotide sequence GCGA, and these sequences might in some cases form stable GNRA tetraloops. Since the two stem-loops are somewhat distant from one another it is possible that they represent two independent non-coding RNAs that are often or always co-transcribed. The region one thousand base pairs upstream of predicted Cyano-2 RNAs is usually devoid of annotated features such as RNA or protein-coding genes. This absence of annotated genes within one thousand base pairs is relatively unusual within bacteria.