Cyano-S1 RNA motif
{{primary sources|date=November 2021}}
{{Infobox rfam
| Name = cyano-S1
| image = RF03151.svg
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| caption = Consensus secondary structure and sequence conservation of Cyanobacterial ribosomal protein S1 leader
| Symbol = cyano-S1
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| Rfam = RF03151
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| SO = {{SO|0000655}}
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The Cyano-S1 RNA motif (originally named the Cyano-30S motif) is a conserved RNA structure present in some species of Cyanobacteria.{{cite journal |author=Weinberg Z |title=Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline |journal=Nucleic Acids Res. |volume=35 |issue=14 |pages=4809–4819 |year=2007 |pmid=17621584 |pmc=1950547 |doi=10.1093/nar/gkm487 |name-list-style=vanc|author2=Barrick JE |author3=Yao Z |display-authors=3 |last4=Roth |first4=A. |last5=Kim |first5=J. N. |last6=Gore |first6=J. |last7=Wang |first7=J. X. |last8=Lee |first8=E. R. |last9=Block |first9=K. F.}} Cyano-S1 RNAs are consistently found upstream of genes encoding ribosomal protein S1, a subunit of the ribosome. Therefore, they are presumed to be ribosomal protein leaders, i.e., cis-regulatory elements to which the ribosomal protein S1 binds, thereby controlling its expression levels.