David Edwards (engineer)

Edwards studied chemical engineering, receiving a BS from Michigan Technological University in the field in 1983, and a PhD in 1987 from the Illinois Institute of Technology.{{cite news |last1=Osgood |first1=Charles |last2=Braver |first2=Rita |title=Does a degree in chemical engineering guarantee that its holder will enjoy the sweet smell of success? |url=https://www.cbsnews.com/news/smell-of-success/ |accessdate=23 September 2020 |agency=CBS Sunday Morning |date=27 September 2015}}{{cite news |last1=Schmadeke |first1=Steve |title=A whiff of innovation--and chocolate |url=https://www.chicagotribune.com/news/ct-xpm-2009-04-10-0904090793-story.html |access-date=24 September 2020 |agency=Chicago Tribune |date=10 April 2009}}

Between 1987 and 1995, Edwards held a postdoctoral and lectureship at the Technion in Israel and the Massachusetts Institute of Technology.{{cite web|title=The Alan S. Michaels Distinguished Lectureship in Medical and Biological Engineering – 2006|url=https://cheme.mit.edu/michaels-lecture-2006/|website=MIT|accessdate=25 September 2020}}{{cite news|last1=Legg|first1=Heidi|date=29 September 2015|title=The Scent of a Cyborg|work=TheEditorial|url=https://www.theeditorial.com/essay/2015/7/27/david-edwards#:~:text=David%20Edwards%2C%20after%20graduate%20studies,which%20patients%20inhale%20insulin%20product |accessdate=25 September 2020}} While at MIT, Robert Langer, a professor at MIT, encouraged Edwards to develop an efficient way for inhalers to deliver medicine to the lungs.{{cite news|last1=Aoki|first1=Naomi|date=25 May 2003|title=MIT Scientist Sees Science As Means to Change the World and He Has|work=The Boston Globe}} Edwards joined the Pennsylvania State University faculty as an Associate Professor of Chemical Engineering in 1995, where he continued to research ways to make medicine inhalable.{{cite news|last1=Aoki|first1=Naomi|date=25 May 2003|title=MIT Scientist Sees Science As Means to Change the World and He Has|work=The Boston Globe}}{{cite web|title=The Alan S. Michaels Distinguished Lectureship in Medical and Biological Engineering – 2006|url=https://cheme.mit.edu/michaels-lecture-2006/|website=MIT|accessdate=25 September 2020}} In 1997, Science published his study on a new type of inhalable aerosol that efficiently delivered drugs to the lungs.{{cite news|last1=Scripps News Service|date=20 June 1997|title=New aerosol particle helps fight lung disorders|work=Deseret News|url=https://www.deseret.com/1997/6/20/19318842/new-aerosol-particle-helps-fight-lung-disorders|accessdate=29 September 2020}}{{cite journal|last1=Edwards|first1=David|last2=Hanes|first2=J|last3=Caponetti|first3=G|last4=Hrkach|first4=J|last5=Ben-Jebria|first5=A|last6=Eskew|first6=M.L.|last7=Mintzes|first7=J|last8=Deaver|first8=D|last9=Lotan|first9=N|last10=Langer|first10=R|date=20 June 1997|title=Large porous particles for pulmonary drug delivery|url=https://pubmed.ncbi.nlm.nih.gov/9188534/|journal=Science|volume=276|issue=5320|pages=1868–1871|doi=10.1126/science.276.5320.1868|pmid=9188534}} Edwards left academia in 1998 when he and Langer founded Advanced Inhalation Research (AIR); the startup was purchased a year later by Alkermes for $114 million.{{cite news|last1=Kirsner|first1=Scott|date=3 March 2013|title=Harvard dreamer looks for ways to link art, science, and commerce: Innovation Economy|work=The Boston Globe|url=https://www.bostonglobe.com/business/2013/03/03/what-will-harvard-david-edwards-dream-next/chUZvx1Zb7QpgTMhsI2EhL/story.html|accessdate=23 September 2020}}{{cite news|last1=Aoki|first1=Naomi|date=25 May 2003|title=MIT Scientist Sees Science As Means to Change the World and He Has|work=The Boston Globe}} He returned to academia in 2002, joining the Harvard faculty.{{cite web|title=The Alan S. Michaels Distinguished Lectureship in Medical and Biological Engineering – 2006|url=https://cheme.mit.edu/michaels-lecture-2006/|website=MIT|accessdate=25 September 2020}}

Edwards' scientific work in biomedical engineering concerns the research and development of drug delivery platforms for treating infectious diseases in the developing world.{{citation needed|date=March 2021}} He was a founder of Advanced Inhalation Research, now part of Alkermes, Inc.,{{citation needed|date=March 2021}} of Pulmatrix,{{citation needed|date=March 2021}} and of Medicine in Need, an international non-governmental organization aimed at developing new drugs and vaccines for diseases of poverty, such as tuberculosis.[https://www.forbes.com/global/2005/0725/028.html "Chutzpah Science"], Forbes, May 25, 2005.[https://www.foxnews.com/story/nose-spray-may-slow-spread-of-germs "Nose Spray May Slow Spread of Germs"], Fox News, November 30, 2004.

In 2020, Edwards founded the company Sensory Cloud. Sensory Cloud released a nasal inhalable product intended to reduce infected air droplets from viruses like SARS-CoV-2, a strain of coronavirus known to cause COVID-19.{{cite news |last1=Wilson |first1=Mark |title=Harvard professor develops a $50 nasal spray to thwart the spread of COVID-19 |url=https://www.fastcompany.com/90524003/harvard-professor-develops-a-50-nasal-spray-to-thwart-the-spread-of-covid-19 |accessdate=23 September 2020 |work=Fast Company |date=8 July 2020}}{{cite magazine |title=The Best Inventions of 2020: 100 innovations changing how we live |url=https://time.com/collection/best-inventions-2020/ |access-date=25 August 2021 |magazine=Time |date=19 November 2020}}

In a February 2021 study in the Proceedings of the National Academy of Sciences of the United States of America, Edwards and his colleagues posited that "exhaled aerosol increases with COVID-19 infection, age, and obesity".{{cite journal |last1=Edwards |first1=David |title=Exhaled aerosol increases with COVID-19 infection, age, and obesity |journal=Proceedings of the National Academy of Sciences of the United States of America |date=23 February 2021 |volume=118 |issue=8 |pages=e2021830118 |doi=10.1073/pnas.2021830118 |pmid=33563754 |pmc=7923364 |bibcode=2021PNAS..11821830E |doi-access=free }}{{cite journal |last1=Hussein |first1=Tareq |last2=Löndahl |first2=Jakob |last3=Thuresson |first3=Sara |last4=Alsved |first4=Malin |last5=Al-Hunaiti |first5=Afnan |last6=Saksela |first6=Kalle |last7=Aqel |first7=Hazem |last8=Junninen |first8=Heikki |last9=Mahura |first9=Alexander |last10=Kulmalla |first10=Markku |title=Indoor Model Simulation for COVID-19 Transport and Exposure |journal=Int. J. Environ. Res. Public Health |date=12 March 2021 |volume=18 |issue=6 |page=2927 |doi=10.3390/ijerph18062927 |pmid=33809366 |pmc=7999367 |doi-access=free }}

In 2007, Edwards opened "Le Lab" as a space for artists, designers, scientists, and the general public to meet for exhibitions, performances, and discussions in Paris,{{cite web |last1=Dessent |first1=Blaire |title=December 2007, Le Laboratoire |url=https://whitehotmagazine.com/articles/december-2007-le-laboratoire/1063 |website=Whitehot Magazine of Contemporary Art |access-date=2022-12-31 |language=en}}{{cite news |last1=Kirsner |first1=Scott |title=Accelerating art, science in Lab Cambridge |url=https://www.bostonglobe.com/business/2013/03/31/highlights-from-scott-kirsner-innovation-economy-blog/KN665674WcgECN5gPJYIJN/story.html |access-date=2023-01-01 |work=Boston Globe |date=April 1, 2013}} and then he moved it to 650 East Kendall Street in the Kendall Square area of Cambridge, Massachusetts in 2014.{{cite web |title=Le Laboratoire Cambridge |url=https://cefloyd.com/our-work/specialty-work/le-laboratoire-cambridge |website=C.E. Floyd |publisher=C.E. Floyd Company, PBC |access-date=2022-12-31}}{{cite web |last1=Zoia |first1=Gabriella |title=Le Laboratoire creates interactive space for groundbreaking innovation in art, science |url=https://tuftsdaily.com/features/2014/11/04/le-laboratoire-creates-interactive-space-groundbreaking-innovation-art-science/ |website=The Tufts Daily |access-date=2023-01-24 |language=en |date=5 November 2014}}{{cite web |last1=Lau |first1=Cat |title=SPACES – Le Laboratoire Cambridge |url=https://artthescience.com/magazine/2017/04/24/spaces-le-laboratoire-cambridge/ |website=Polyfield Magazine |access-date=2023-01-24 |date=April 24, 2017}} Major exhibitions by artists such as Mark Dion{{cite news |last1=Gayla |first1=Marella A |title=The Trouble with Jellyfish |url=https://www.thecrimson.com/article/2015/11/5/jellyfish/ |access-date=2022-12-31 |work=The Harvard Crimson |date=November 5, 2015}}{{cite news |title='The Trouble with Jellyfish' |url=https://news.harvard.edu/gazette/story/2015/10/the-trouble-with-jellyfish/ |access-date=2022-12-31 |work=Harvard Gazette |publisher=Harvard University |date=26 October 2015}} and artist/engineer Chuck Hoberman{{cite web |last1=Phongsirivech |first1=Pimploy |title=See Transformable Structures at Le Lab Cambridge |url=https://www.bostonmagazine.com/arts-entertainment/2016/10/26/chuck-hoberman-10-degrees-le-lab/ |website=Boston Magazine |access-date=2023-01-01 |date=26 October 2016}}{{cite web |title=10° (Ten Degrees) |url=https://www.hoberman.com/portfolio/10-ten-degrees/ |website=Hoberman Associates |access-date=2023-01-01}} were shown, as well as innovations developed by Edwards, his associates, and his students. Some of his food-related inventions were available for purchase at Cafe ArtScience, an innovative restaurant associated with Le Laboratoire Cambridge.{{cite news |last1=Jiang |first1=Nancy |title=Cambridge Café ArtScience explores the future of food |url=https://dailyfreepress.com/2019/09/19/cambridge-cafe-artscience-explores-the-future-of-food/?fbclid=IwAR1gePgPYtMrFlaWYgV5et63-iUx9UAoXv-1bl6VJYO6RBBgorRO8tywxnU |access-date=2023-01-01 |work=The Daily Free Press |date=September 19, 2019}} In December 2019, it was announced that Cafe ArtScience was closing after 5 years of operation, and would be replaced by a new restaurant, called "Senses".{{cite web |last1=Blumenthal |first1=Rachel Leah |title=Cafe Artscience Is Closing in Cambridge After Five Years |url=https://boston.eater.com/2019/12/20/21032220/cafe-artscience-cambridge-closing-december-2019 |website=Eater Boston |access-date=2023-01-01 |language=en |date=20 December 2019}}

However, the COVID-19 pandemic disrupted these plans, and {{asof|2022|lc=y}}, both the restaurant and Le Laboratoire Cambridge appear to be inactive or closed, either temporarily or permanently.

Edwards, his wife and three children have lived alternately in Boston and Paris.{{cite news |last1=Kirsner |first1=Scott |title=Harvard dreamer looks for ways to link art, science, and commerce: Innovation Economy |url=https://www.bostonglobe.com/business/2013/03/03/what-will-harvard-david-edwards-dream-next/chUZvx1Zb7QpgTMhsI2EhL/story.html |accessdate=23 September 2020 |work=The Boston Globe |date=3 March 2013}}

• {{cite book |last1=Edwards |first1=David |last2=Cantor |first2=Jay |title=Niche |date=2008 |publisher=Harvard University Press |isbn=9780674027909}}
• {{cite book |last1=Edwards |first1=David |title=Whiff |date=2009 |publisher=Harvard University Press |isbn=9780674032866}}
• {{cite book |last1=Edwards |first1=David |title=ArtScience: Creativity in the Post-Google Era |date=2010 |publisher=Harvard University Press |isbn=978-0674034648}}
• {{cite book |last1=Edwards |first1=David |title=The Lab: Creativity and Culture |date=2010 |publisher=Harvard University Press |isbn=978-0-674-05719-7}}
• {{cite book |last1=Edwards |first1=David |title=Creating Things That Matter: The Art and Science of Innovations That Last. |date=2019 |publisher=Picador |isbn=978-1-250-23071-3}}
• {{cite journal |last1=Edwards |first1=D.A. |title=The macrotransport theory of nondepositing particles in the lung by convective dispersion. |journal=Journal of Aerosol Science |date=April 1994 |volume=25 |issue=3 |pages=533–565 |doi=10.1016/0021-8502(94)90071-X |url=https://www.sciencedirect.com/science/article/abs/pii/002185029490071X |access-date=17 April 2021}}
• {{cite journal |last1=Edwards |first1=D.A. |title=The macrotransport theory of lung dispersion: Aerosol deposition phenomena. |journal=Journal of Aerosol Science |date=March 1995 |volume=26 |issue=2 |pages=293–317 |doi=10.1016/0021-8502(94)00101-4 |url=https://www.sciencedirect.com/science/article/abs/pii/0021850294001014 |access-date=17 April 2021}}
• {{cite journal |last1=Li |first1=W. -I |last2=Perzl |first2=M.P. |last3=Ferron |first3=G.A. |last4=Batycky |first4=R. |last5=Heyder |first5=J. |last6=Edwards |first6=D.A. |title=The macrotransport properties of aerosol particles in the human oral-pharyngeal region |journal=Journal of Aerosol Science |date=September 1998 |volume=29 |issue=8 |pages=995–1010 |doi=10.1016/S0021-8502(97)10040-4 |bibcode=1998JAerS..29..995L |url=https://www.sciencedirect.com/science/article/abs/pii/S0021850297100404#! |access-date=17 April 2021}}
• {{cite journal |last1=Edwards |first1=D.A. |last2=Chen |first2=D. |last3=Wang |first3=J. |last4=Ben-Jebria |first4=A. |title=Controlled release inhalation aerosols. |journal=Resp. Drug Delivery VI |date=1998 |pages=187–192}}
• {{cite journal |last1=Wang |first1=J. |last2=Ben-Jebria |first2=A. |last3=Edwards |first3=D.A. |title=Inhalation of estradiol for sustained systemic delivery. |journal=Journal of Aerosol Medicine |date=1999 |volume=12 |issue=1 |pages=27–36 |doi=10.1089/jam.1999.12.27 |pmid=10351127 |url=https://pubmed.ncbi.nlm.nih.gov/10351127/}}
• {{cite journal |last1=Tsapis |first1=N. |last2=Bennett |first2=D. |last3=Jackson |first3=B. |last4=Weitz |first4=D.A. |last5=Edwards |first5=D.A. |title=Large porous carriers of nanoparticles for drug delivery. |journal=Proceedings of the National Academy of Sciences |date=September 2002 |volume=99 |issue=19 |pages=12001–12005 |doi=10.1073/pnas.182233999 |pmid=12200546 |pmc=129387 |doi-access=free }}
• {{cite journal |last1=Wong |first1=Y-L. |last2=Sampson |first2=S. |last3=Germishuizen |first3=W. |last4=Goonesekera |first4=S. |last5=Caponetti |first5=G. |last6=Sadoff |first6=J. |last7=Bloom |first7=B.R. |last8=Edwards |first8=D.A. |title=Drying a tuberculosis vaccine without freezing. |journal=Proceedings of the National Academy of Sciences |date=February 2007 |volume=104 |issue=8 |pages=2591–2505 |doi=10.1073/pnas.0611430104 |pmid=17299039 |pmc=1815227 |bibcode=2007PNAS..104.2591W |doi-access=free }}

{{reflist}}

• [http://people.seas.harvard.edu/~dedwards/ Edwards' web site]

{{Authority control}}

{{DEFAULTSORT:Edwards, David}}

Category:Living people

Category:American biomedical engineers

Category:Michigan Technological University alumni

Category:Illinois Institute of Technology alumni

Category:MIT School of Engineering faculty

Category:Pennsylvania State University faculty

Category:Harvard John A. Paulson School of Engineering and Applied Sciences faculty

Category:1961 births