Diamond Light Source

{{Short description|Scientific facility in Oxfordshire, England}}

{{Use dmy dates|date=April 2022}}

{{Infobox laboratory

| name = Diamond Light Source

| logo = DiamondLogo.png

| logo_size = 180px

| image = Diamond Light Source building - 3338870 ff7a8854.jpg

| image_size = 300px

| caption = Diamond Light Source building

| map =

| mcaption =

| lab_type = National scientific research laboratory

| city = Chilton, Oxfordshire

| membership =

| language =

| head = Professor Andrew Harrison

| country = England

| location_map = Oxfordshire

| coordinates = {{Coord|51|34|28|N|1|18|39|W|region:GB-OXF_type:landmark_source:dewiki|display=title}}

| established = {{Start date|2001}}

| website = {{URL|www.diamond.ac.uk/}}

}}

Diamond Light Source (or Diamond) is the UK's national synchrotron light source science facility located at the Harwell Science and Innovation Campus in Oxfordshire.

Its purpose is to produce intense beams of light whose special characteristics are useful in many areas of scientific research. In particular it can be used to investigate the structure and properties of a wide range of materials from proteins (to provide information for designing new and better drugs), and engineering components (such as a fan blade from an aero-engine[http://www.diamond.ac.uk/Home/Media/LatestNews/02_12_10.html Diamond and Rolls-Royce shine light on world’s biggest synchrotron stage]) to conservation of archeological artifacts (for example Henry VIII's flagship the Mary Rose[http://www.diamond.ac.uk/Home/Media/LatestNews/7February2008.html High-tech conservation solutions for old warship – Diamond Lights Source][http://nakeddiscovery.com/downloads/split_individual/09.10.29/Naked_Scientists_Show_09.10.29_4852.mp3 Podcast – Dr Mark Jones from The Mary Rose Trust discusses his research]).

There are more than 50 light sources across the world.{{Cite web|url=https://lightsources.org/lightsources-of-the-world/|title=Lightsources.org: Light Sources of the World|date=2019|access-date=2019-10-05}} With an energy of 3 GeV, Diamond is a medium energy synchrotron currently operating with 32 beamlines.

Design, construction and finance

File:Diamond Snow Outside PlateBlur.jpg

The Diamond synchrotron is the largest UK-funded scientific facility to be built in the UK since the Nimrod proton synchrotron which was sited at the Rutherford Appleton Laboratory in 1964. Nearby facilities include the ISIS Neutron and Muon Source, the Central Laser Facility, and the laboratories at Harwell and Culham (including the Joint European Torus (JET) project). It replaced the Synchrotron Radiation Source, a second-generation synchrotron at the Daresbury Laboratory in Cheshire.

Diamond produced its first user beam towards the end of January 2007, and was formally opened by Queen Elizabeth II on 19 October 2007.[http://www.diamond.ac.uk/Home/Media/LatestNews/October2007.html Diamond News: Her Majesty The Queen Officially Opens Diamond Light Source]{{Cite news | url=http://news.bbc.co.uk/1/hi/sci/tech/6331883.stm |title = 'Super-scope' opens for business|date = 2007-02-05}}

=Construction=

A design study during the 1990s was completed in 2001 by scientists at Daresbury and construction began following the creation of the operating company, Diamond Light Source Ltd.The name DIAMOND was originally conceived by Mike Poole (the originator of the DIAMOND project) and stood as an acronym meaning DIpole And Multipole Output for the Nation at Daresbury. With the location now being Oxfordshire, not Daresbury, the name reflects the synchrotron light being both hard (referring to the "hard" X-ray region of the electromagnetic spectrum) and bright.

The construction costs of £260m covered the synchrotron building, the accelerators inside it, the first seven experimental stations (beamlines) and the adjacent office block, Diamond House.

=Governance=

The facility is operated by Diamond Light Source Ltd,[http://www.diamond.ac.uk/Home/About/Company.html Diamond Light Source Ltd] {{webarchive|url=https://web.archive.org/web/20130707191907/http://www.diamond.ac.uk/Home/About/Company.html |date=2013-07-07 }} a joint venture company established in March 2002. The company receives 86% of its funding from the UK Government via the Science and Technology Facilities Council (STFC) and 14% from the Wellcome Trust.

Synchrotron

File:Diamond Inside Panorama.jpg

Diamond generates synchrotron light at wavelengths ranging from X-rays to the far infrared. This is also known as synchrotron radiation and is the electromagnetic radiation emitted by charged particles travelling near the speed of light when their path deviates from a straight line.Strictly speaking, when they experience an acceleration perpendicular to their direction of travel. It is used in a huge variety of experiments to study the structure and behaviour of many different types of matter.

The particles Diamond uses are electrons travelling at an energy of 3 GeVEquivalent to accelerating them through a voltage of 3 billion volts; 1 electronvolt is the energy an electron gains when accelerated by a potential difference of 1 volt. round a {{cvt|561.6|m}} circumference storage ring. This is not a true circle, but a 48-sided polygon with a bending magnet at each vertex and straight sections in between.{{cite web |title=Inside Diamond |url=http://extranet2.diamond.ac.uk/ISV/Flipping/InsideDiamond/Summer2015/InsidediamondSummer2015.pdf |year=2015 |publisher=Diamond Light Source |access-date=5 Oct 2019 |archive-date=20 November 2018 |archive-url=https://web.archive.org/web/20181120185623/http://extranet2.diamond.ac.uk/ISV/Flipping/InsideDiamond/Summer2015/InsidediamondSummer2015.pdf |url-status=dead }} The bending magnets are dipole magnets whose magnetic field deflects the electrons so as to steer them around the ring. As Diamond is a third generation light source{{explain|date=September 2021}} it also uses special arrays of magnets called insertion devices. These cause the electrons to undulate and it is their sudden change of direction that causes the electrons to emit an exceptionally bright beam of electromagnetic radiation, brighter than that of a single bend when traveling through a bending magnet. This is the synchrotron light used for experiments. Some beamlines, however, use light solely from a bending magnet without the need of an insertion device.

The electrons reach this high energy via a series of pre-accelerator stages before being injected into the 3 GeV storage ring:

The Diamond synchrotron is housed in a silver toroidal building of {{cvt|738|m}} in circumference, covering an area in excess of {{cvt|43300|m2}}, or the area of over six football pitches. This contains the storage ring and a number of beamlines,{{Cite web |url=http://www.diamond.ac.uk/Home/Beamlines.html |title=Current list of Diamond Beamlines |access-date=2011-08-09 |archive-url=https://web.archive.org/web/20160202001944/http://www.diamond.ac.uk/Home/Beamlines.html |archive-date=2016-02-02 |url-status=dead }} with the linear accelerator and booster synchrotron housed in the centre of the ring. These beamlines are the experimental stations where the synchrotron light's interaction with matter is used for research purposes. Seven beamlines were available when Diamond became operational in 2007, with more coming online as construction continued. As of April 2019 there were 32 beamlines in operation. Diamond is intended ultimately to host about 33 beamlines, supporting the life, physical and environmental sciences.

Diamond is also home to eleven electron microscopes. Nine of these are cryo-electron microscopes specialising in life sciences including two provided for industry use in partnership with Thermo Fisher Scientific; the remaining two microscopes are dedicated to research of advanced materials.{{Cite web|url=https://www.diamond.ac.uk/Home/Corporate-Literature/Annual-Review/Review2019/Beamline-Development-and-Technical-Summary.html|title=Beamline Development and Technical Summary - Diamond Light Source|website=www.diamond.ac.uk|access-date=2019-10-05}}

Case studies

  • In September 2007, scientists from Cardiff University led by Tim Wess, found that the Diamond synchrotron could be used to see hidden content of ancient documents by illumination without opening them (penetrating layers of parchment).{{Cite news | url=http://news.bbc.co.uk/2/hi/science/nature/6991893.stm |title = 'Super-scope' to see hidden texts|date = 2007-09-13}}{{Cite web |url=http://www.diamond.ac.uk/Home/Beamlines/small-angle/Case-Studies/casestudy3.html |title=Diamond: Unravelling the secrets of ancient parchments |access-date=2011-08-09 |archive-url=https://web.archive.org/web/20110808154341/http://www.diamond.ac.uk/Home/Beamlines/small-angle/Case-Studies/casestudy3.html |archive-date=2011-08-08 |url-status=dead }}
  • In November 2010 data collected at Diamond by Imperial College London formed the basis for a paper in the journal Nature advancing the understanding of how HIV and other retroviruses infect human and animal cells.[http://www.diamond.ac.uk/Home/Media/LatestNews/10_11_10.html Diamond News: X-rays illuminate the mechanism used by HIV to attack human DNA]{{Cite journal | doi=10.1038/nature09517| pmid=21068843| pmc=2999894| title=The mechanism of retroviral integration from X-ray structures of its key intermediates| journal=Nature| volume=468| issue=7321| pages=326–329| year=2010| last1=Maertens| first1=Goedele N.| last2=Hare| first2=Stephen| last3=Cherepanov| first3=Peter| bibcode=2010Natur.468..326M}} The findings may enable improvements in gene therapy to correct gene malfunctions.
  • In June 2011 data from Diamond led to an article in the journal Nature detailing the 3D structure of the human Histamine H1 receptor protein. This led to the development of 'third generation' anti-histamines, drugs effective against some allergies without adverse side-effects.[http://www.diamond.ac.uk/Home/Media/LatestNews/22_06_11.html Diamond News: Histamine H1 receptor breakthrough heralds improved allergy treatments]{{cite journal | doi = 10.1038/nature10236 | pmid=21697825 | volume=475 | issue=7354 | title=Structure of the human histamine H1 receptor complex with doxepin | year=2011 | journal=Nature | pages=65–70 | last1 = Shimamura | first1 = Tatsuro| pmc=3131495 }}
  • In December 2017, UK established the Synchrotron Techniques for African Research and Technology (START) with a £3.7 million funded by the UK Research and Innovation for 3 years. START aimed to provide access to African researchers with focus on energy materials and structural biology. The step is circuital for the inception of the first African Light Source.{{Cite web |title=GCRF - START: Synchrotron Techniques for African Research and Technology |url=https://gtr.ukri.org/projects?ref=ST%2FR002754%2F1}}{{Cite journal |last1=Nicklin |first1=Chris |last2=Stredwick |first2=Rebekka |last3=Sewell |first3=Trevor |date=2022-01-02 |title=Synchrotron Techniques for African Research and Technology: A Step-Change in Structural Biology and Energy Materials |journal=Synchrotron Radiation News |volume=35 |issue=1 |pages=14–19 |bibcode=2022SRNew..35a..14N |doi=10.1080/08940886.2022.2043684 |issn=0894-0886 |s2cid=247431515|doi-access=free }}
  • Published in the [https://www.pnas.org/content/115/19/E4350 Proceedings of the National Academy of Sciences] in April 2018, a five institution collaboration including scientists from Diamond used three of Diamond's macromolecular beamlines to discover details of how a bacterium used plastic as an energy source. High resolution data allowed the researchers to determine the workings of an enzyme that degraded the plastic PET. Subsequently computational modelling was carried out to investigate and thus improve this mechanism.{{Cite web|url=https://www.diamond.ac.uk/Home/News/LatestNews/2018/16-04-2018.html|title=Solution to plastic pollution on the horizon - Diamond Light Source|last=Diamond Light Source|website=www.diamond.ac.uk|language=en|access-date=2019-10-05}}
  • An article published in [https://www.nature.com/articles/s41929-019-0334-3 Nature] in 2019 described how a worldwide multidisciplinary collaboration designed several ways to control metal nano-particles, including synthesis at a substantially reduced cost for use as catalysts for the production of everyday goods.{{Cite web|url=https://www.diamond.ac.uk/Home/News/LatestNews/2019/30-09-2019.html|title=Worldwide scientific collaboration develops catalysis breakthrough - Diamond Light Source|website=www.diamond.ac.uk|access-date=2019-10-05}}
  • Research conducted at Diamond Light Source in 2020 helped determine the atomic structure of SARS‑CoV‑2, the virus responsible for COVID-19.{{Cite web|url=https://cerncourier.com/a/synchrotrons-on-the-coronavirus-frontline/|title=Synchrotrons on the coronavirus frontline|date=2020|access-date=2021-07-03}}
  • In 2023, Diamond Light Source scanned the Herculaneum papyri including scroll PHerc. Paris. 4 to facilitate non-invasive decipherment through machine learning.{{Cite web |author1=Laura Geggel |date=2024-02-07 |title=Scroll charred in Mount Vesuvius eruption partially deciphered, earning researchers $700,000 prize |url=https://www.livescience.com/archaeology/romans/scroll-charred-in-mount-vesuvius-eruption-partially-deciphered-earning-researchers-dollar700000-prize |access-date=2024-02-08 |website=livescience.com |language=en}}

= Insects study =

Using X-ray beamlines, researchers examine insect specimens from the London Natural History Museum's collection, which contains millions of uncatalogued insects. The synchrotron’s imaging technology provides detailed views of anatomical features, such as wing structures and mandibles, revealing evolutionary adaptations and ecological roles.{{Cite news |last=Peel |first=Michael |date=2025-05-03 |title=Inside the Large Hadron Collider for smashing bugs |url=https://www.ft.com/content/ccbbcb4a-992f-426b-ae63-97f2770b1655 |access-date=2025-05-04 |work=Financial Times}}

Studies investigated the documented decline in insect populations, with research indicating a 45% reduction over four decades, attributed to factors like habitat loss, pesticides and climate change. By analyzing both fossilized and modern specimens, researchers explored how insects responded to past environmental changes, providing data relevant to current biodiversity challenges. The synchrotron’s ability to process large 3D image datasets facilitates the identification of uncatalogued specimens and supports studies on species critical to pollination and food chains.

Research also examined insect responses to contemporary issues, such as microplastic accumulation and geographic shifts due to climate change. For example, comparisons of historical and modern butterfly specimens help track range changes in the UK. These studies contribute to understanding insect evolution and ecology, offering insights into conservation and the broader impacts of environmental change on ecosystems.

See also

References

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