Estriol sulfate glucuronide

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| ImageFile = Estriol 3-sulfate 16α-glucuronide.svg

| ImageSize = 250px

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| IUPACName = (2S,3S,4S,5R)-3,4,5-Trihydroxy-6-{[(1S,10R,11S,13R,14R,15S)-14-hydroxy-15-methyl-5-(sulfooxy)tetracyclo[8.7.0.02,7.011,15]heptadeca-2(7),3,5-trien-13-yl]oxy}oxane-2-carboxylic acid

| OtherNames = Estriol 3-sulfate 16α-glucuronide; 17β-Hydroxy-3-(sulfooxy)estra-1,3,5(10)-trien-16α-yl-β-D-glucopyranosiduronic acid

| Section1 = {{Chembox Identifiers

| CASNo = 4661-65-8

| ChemSpiderID = 133283

| PubChem = 151223

| StdInChI = 1S/C24H32O12S/c1-24-7-6-13-12-5-3-11(36-37(31,32)33)8-10(12)2-4-14(13)15(24)9-16(21(24)28)34-23-19(27)17(25)18(26)20(35-23)22(29)30/h3,5,8,13-21,23,25-28H,2,4,6-7,9H2,1H3,(H,29,30)(H,31,32,33)/t13-,14-,15+,16-,17+,18+,19-,20+,21+,23?,24+/m1/s1

(H,31,32,33)/t13-,14-,15+,16-,17+,18+,19-,20+,21+,23?,24+/m1/s1

| StdInChIKey = ATNWFRGUDKUYOG-SUPAOECSSA-N

| SMILES = [H][C@@]12C[C@@H](OC3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H](O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(OS(O)(=O)=O)C=C3

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| Section2 = {{Chembox Properties

| C=24 | H=32 | O=12 | S=1

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Estriol sulfate glucuronide, or estriol 3-sulfate 16α-glucuronide, is an endogenous, naturally occurring diconjugated metabolite of estriol.{{Cite web|url=http://www.hmdb.ca/metabolites/HMDB10356|title = Human Metabolome Database: Showing metabocard for Estriol 3-sulfate 16-glucuronide (HMDB0010356)}} It is generated in the liver from estriol sulfate by UDP-glucuronyltransferase and is eventually excreted in the urine by the kidneys. It occurs in high concentrations during pregnancy along with estriol sulfate and estriol glucuronide,{{cite book|author=N. S. Assali|title=The Maternal Organism|url=https://books.google.com/books?id=mSzLBAAAQBAJ&pg=PA339|date=3 September 2013|publisher=Elsevier|isbn=978-1-4832-6380-9|pages=339–}} and was a component of the early pharmaceutical estrogens Progynon and Emmenin.{{cite book|author=Thom Rooke|title=The Quest for Cortisone|url=https://books.google.com/books?id=70vvFrtpePoC&pg=PT54|date=1 January 2012|publisher=MSU Press|isbn=978-1-60917-326-5|pages=54–}}{{cite book|author=Gregory Pincus|title=Recent Progress in Hormone Research: The Proceedings of the Laurentian Hormone Conference|url=https://books.google.com/books?id=jgTgBAAAQBAJ&pg=PA307|date=22 October 2013|publisher=Elsevier Science|isbn=978-1-4832-1945-5|pages=307–}}{{cite book|author1=Robert K. Creasy|author2=Robert Resnik|author3=Charles J. Lockwood |author4=Jay D. Iams |author5=Michael F. Greene |author6=Thomas Moore |title=Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice|url=https://books.google.com/books?id=AbMKAQAAQBAJ&pg=PA104|year=2013|publisher=Elsevier Health Sciences|isbn=978-1-4557-1137-6|pages=104–}}

See also

References

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