Ethylnorepinephrine

{{Short description|Chemical compound}}

{{Drugbox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 458630626

| IUPAC_name = 4-(2-amino-1-hydroxybutyl)benzene-1,2-diol

| image = Ethylnorepinephrine.svg

| width = 180

| tradename =

| pregnancy_category =

| legal_status = Rx-only

| routes_of_administration =

| bioavailability =

| metabolism =

| elimination_half-life =

| excretion =

| CAS_number_Ref = {{cascite|changed|??}}

| CAS_number = 536-24-3

| ATC_prefix = None

| ATC_suffix =

| ChEMBL_Ref = {{ebicite|correct|EBI}}

| ChEMBL = 31159

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C10H15NO3/c1-2-7(11)10(14)6-3-4-8(12)9(13)5-6/h3-5,7,10,12-14H,2,11H2,1H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = LENNRXOJHWNHSD-UHFFFAOYSA-N

| PubChem = 18538

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank =

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 17508

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = M6AY4VCZ0A

| synonyms = β,3,4-Trihydroxy-α-ethyl-2-phenylethylamine

| C=10 | H=15 | N=1 | O=3

| SMILES = Oc1ccc(cc1O)C(O)C(N)CC

}}

Ethylnorepinephrine, sold under the brand names Etanor, Bronkephrine, and Butanefrine, is a sympathomimetic and bronchodilator medication related to norepinephrine.{{cite book | author = David J. Triggle | title = Dictionary of Pharmacological Agents | publisher = Chapman & Hall/CRC | location = Boca Raton | year = 1996 | isbn = 0-412-46630-9 | url = https://books.google.com/books?id=DeX7jgInYFMC&pg=PA91}}{{cite journal | author = KORNEL L | title = A case of calcified ventricular aneurysm with progressive heart block; observations on the effect of ethylnorepinephrine | journal = Cardiologia | volume = 32 | issue = 2 | pages = 101–9 | year = 1958 | pmid = 13500349 | doi = 10.1159/000165806}}{{cite journal |vauthors=CHRISTENSEN JM, VALASEK FE, TAINTER ML | title = Ethylnorepinephrine; a unique bronchodilator | journal = American Practitioner and Digest of Treatment | volume = 9 | issue = 6 | pages = 916–21 |date=June 1958 | pmid = 13533786 }} It activates both α and β adrenergic receptors.{{cite book|last1=Turner|first1=Robert A.|title=Screening Methods in Pharmacology|url=https://archive.org/details/screeningmethods00turn|url-access=registration|date=1965|publisher=Academic Press Inc.|location=New York|page=[https://archive.org/details/screeningmethods00turn/page/150 150]|isbn=1483255913|chapter=12. Sympatholytic Agents. VI. The Two Kinds of Receptors}}

Patent:Suter Chester Merle & Ruddy Arlo Wayne, {{US patent|2431285}} (1947 to Winthrop Stearns Inc).