Extended-spectrum penicillin

{{Short description|Group of antibiotics that have the widest antibacterial spectrum of all penicillins}}

The extended-spectrum penicillins are a group of antibiotics that have the widest antibacterial spectrum of all penicillins.Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p917 Some sources identify them with antipseudomonal penicillins,{{cite book |last1=Kester |first1=Mark |last2=Karpa |first2=Kelly Dowhower |last3=Vrana |first3=Kent E. |authorlink3=Kent Vrana |title=Elsevier's Integrated Review Pharmacology E-Book |date=2011 |publisher=Elsevier Health Sciences |isbn=9781455727032 |url=https://books.google.com/books?id=kU6gilUvbSkC&pg=PA48}} others consider these types to be distinct.{{cite book |editor-last1=Clark |editor-first1=Michelle A. |editor-last2=Harvey |editor-first2=Richard A. |editor-last3=Finkel |editor-first3=Richard |editor-last4=Rey |editor-first4=Jose A. |editor-last5=Whalen |editor-first5=Karen |title=Pharmacology |date=2011 |publisher=Lippincott Williams & Wilkins |isbn=9781451113143 |page=383 |url=https://books.google.com/books?id=Y558dgp_PjoC&pg=PA383}} This group includes the carboxypenicillins and the ureidopenicillins. Aminopenicillins, in contrast, do not have activity against Pseudomonas species, as their positively charged amino group does not hinder degradation by bacterially produced beta-lactamases.{{cite book|last=Golan|first=David E.|title=Principles of Pharmacology|date=15 December 2011|publisher=Lippincott Williams & Wilkins|isbn=978-1608312702|page=610|edition=2}}