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GIMAP4

{{Short description|Type of enzyme}}

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GTPase IMAP family member 4 is an enzyme that in humans is encoded by the GIMAP4 gene.{{cite journal |vauthors=Krucken J, Schroetel RM, Muller IU, Saidani N, Marinovski P, Benten WP, Stamm O, Wunderlich F | title = Comparative analysis of the human gimap gene cluster encoding a novel GTPase family | journal = Gene | volume = 341 | pages = 291–304 |date=Oct 2004 | pmid = 15474311 | doi = 10.1016/j.gene.2004.07.005 }}{{cite journal |vauthors=Filen JJ, Filen S, Moulder R, Tuomela S, Ahlfors H, West A, Kouvonen P, Kantola S, Bjorkman M, Katajamaa M, Rasool O, Nyman TA, Lahesmaa R | title = Quantitative proteomics reveals GIMAP family proteins 1 and 4 to be differentially regulated during human T helper cell differentiation | journal = Mol Cell Proteomics | volume = 8 | issue = 1 | pages = 32–44 |date=Jan 2009 | pmid = 18701445 | pmc = 2621005 | doi = 10.1074/mcp.M800139-MCP200 | doi-access = free }}{{cite web | title = Entrez Gene: GIMAP4 GTPase, IMAP family member 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55303}}

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1.

References

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Further reading

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  • {{cite journal |vauthors=Dominguez O, Ashhab Y, Sabater L |title=Cloning of ARE-containing genes by AU-motif-directed display. |journal=Genomics |volume=54 |issue= 2 |pages= 278–86 |year= 1999 |pmid= 9828130 |doi= 10.1006/geno.1998.5548 |display-authors=etal}}
  • {{cite journal |vauthors=Dias Neto E, Correa RG, Verjovski-Almeida S |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=10.1073/pnas.97.7.3491 | pmc=16267 |bibcode=2000PNAS...97.3491D |display-authors=etal|doi-access=free }}
  • {{cite journal |vauthors=Stamm O, Krücken J, Schmitt-Wrede HP |title=Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36. |journal=Gene |volume=282 |issue= 1–2 |pages= 159–67 |year= 2002 |pmid= 11814688 |doi=10.1016/S0378-1119(01)00837-X |display-authors=etal}}
  • {{cite journal |vauthors=Cambot M, Aresta S, Kahn-Perlès B |title=Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells. |journal=Blood |volume=99 |issue= 9 |pages= 3293–301 |year= 2002 |pmid= 11964296 |doi=10.1182/blood.V99.9.3293 |display-authors=etal|doi-access=free }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
  • {{cite journal |vauthors=Scherer SW, Cheung J, MacDonald JR |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 | pmc=2882961 |doi= 10.1126/science.1083423 |bibcode=2003Sci...300..767S |display-authors=etal}}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
  • {{cite journal |vauthors=Nitta T, Nasreen M, Seike T |title=IAN family critically regulates survival and development of T lymphocytes. |journal=PLOS Biol. |volume=4 |issue= 4 |pages= e103 |year= 2006 |pmid= 16509771 |doi= 10.1371/journal.pbio.0040103 | pmc=1393758 |display-authors=etal |doi-access=free }} {{open access}}

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