TAL1

TAL1 has been shown to interact with:

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• CBFA2T3,
• EP300,{{cite journal | vauthors = Huang S, Qiu Y, Stein RW, Brandt SJ | title = p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein | journal = Oncogene | volume = 18 | issue = 35 | pages = 4958–67 | date = September 1999 | pmid = 10490830 | doi = 10.1038/sj.onc.1202889 | doi-access = free }}
• GATA1,
• LDB1,{{cite journal | vauthors = Goardon N, Lambert JA, Rodriguez P, Nissaire P, Herblot S, Thibault P, Dumenil D, Strouboulis J, Romeo PH, Hoang T | title = ETO2 coordinates cellular proliferation and differentiation during erythropoiesis | journal = EMBO J. | volume = 25 | issue = 2 | pages = 357–66 | date = January 2006 | pmid = 16407974 | pmc = 1383517 | doi = 10.1038/sj.emboj.7600934 }}
• LMO1,{{cite journal | vauthors = Valge-Archer VE, Osada H, Warren AJ, Forster A, Li J, Baer R, Rabbitts TH | title = The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 91 | issue = 18 | pages = 8617–21 | date = August 1994 | pmid = 8078932 | pmc = 44657 | doi = 10.1073/pnas.91.18.8617| bibcode = 1994PNAS...91.8617V | doi-access = free }}{{cite journal | vauthors = Wadman I, Li J, Bash RO, Forster A, Osada H, Rabbitts TH, Baer R | title = Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia | journal = EMBO J. | volume = 13 | issue = 20 | pages = 4831–9 | date = October 1994 | pmid = 7957052 | pmc = 395422 | doi = 10.1002/j.1460-2075.1994.tb06809.x}}
• LMO2,{{cite journal | vauthors = Osada H, Grutz G, Axelson H, Forster A, Rabbitts TH | title = Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1 | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 92 | issue = 21 | pages = 9585–9 | date = October 1995 | pmid = 7568177 | pmc = 40846 | doi = 10.1073/pnas.92.21.9585| bibcode = 1995PNAS...92.9585O | doi-access = free }}
• SIN3A,{{cite journal | vauthors = Huang S, Brandt SJ | title = mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor | journal = Mol. Cell. Biol. | volume = 20 | issue = 6 | pages = 2248–59 | date = March 2000 | pmid = 10688671 | pmc = 110841 | doi = 10.1128/mcb.20.6.2248-2259.2000}}
• Sp1 transcription factor,{{cite journal | vauthors = Lécuyer E, Herblot S, Saint-Denis M, Martin R, Begley CG, Porcher C, Orkin SH, Hoang T | title = The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1 | journal = Blood | volume = 100 | issue = 7 | pages = 2430–40 | date = October 2002 | pmid = 12239153 | doi = 10.1182/blood-2002-02-0568 | doi-access = free }} and
• TCF3.{{cite journal | vauthors = Hsu HL, Wadman I, Baer R | title = Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 91 | issue = 8 | pages = 3181–5 | date = April 1994 | pmid = 8159721 | pmc = 43539 | doi = 10.1073/pnas.91.8.3181| bibcode = 1994PNAS...91.3181H | doi-access = free }}

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{{reflist}}

{{refbegin | 2}}

• {{cite journal | vauthors = Green AR, Begley CG | title = SCL and related hemopoietic helix-loop-helix transcription factors. | journal = Int. J. Cell Cloning | volume = 10 | issue = 5 | pages = 269–76 | year = 1993 | pmid = 1453013 | doi = 10.1002/stem.5530100504 }}
• {{cite journal | vauthors = Aplan PD, Lombardi DP, Reaman GH, Sather HN, Hammond GD, Kirsch IR | title = Involvement of the putative hematopoietic transcription factor SCL in T-cell acute lymphoblastic leukemia. | journal = Blood | volume = 79 | issue = 5 | pages = 1327–33 | year = 1992 | pmid = 1311214 | doi = 10.1182/blood.V79.5.1327.1327| doi-access = free }}
• {{cite journal | vauthors = Aplan PD, Nakahara K, Orkin SH, Kirsch IR | title = The SCL gene product: a positive regulator of erythroid differentiation. | journal = EMBO J. | volume = 11 | issue = 11 | pages = 4073–81 | year = 1992 | pmid = 1396592 | pmc = 556917 | doi = 10.1002/j.1460-2075.1992.tb05500.x}}
• {{cite journal | vauthors = Goldfarb AN, Goueli S, Mickelson D, Greenberg JM | title = T-cell acute lymphoblastic leukemia--the associated gene SCL/tal codes for a 42-Kd nuclear phosphoprotein. | journal = Blood | volume = 80 | issue = 11 | pages = 2858–66 | year = 1992 | pmid = 1450410 | doi = 10.1182/blood.V80.11.2858.bloodjournal80112858| doi-access = free }}
• {{cite journal | vauthors = Bernard O, Lecointe N, Jonveaux P, Souyri M, Mauchauffé M, Berger R, Larsen CJ, Mathieu-Mahul D | title = Two site-specific deletions and t(1;14) translocation restricted to human T-cell acute leukemias disrupt the 5' part of the tal-1 gene. | journal = Oncogene | volume = 6 | issue = 8 | pages = 1477–88 | year = 1991 | pmid = 1886719 }}
• {{cite journal | vauthors = Bernard O, Guglielmi P, Jonveaux P, Cherif D, Gisselbrecht S, Mauchauffe M, Berger R, Larsen CJ, Mathieu-Mahul D | title = Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T-cell leukemias. | journal = Genes Chromosomes Cancer | volume = 1 | issue = 3 | pages = 194–208 | year = 1991 | pmid = 1964581 | doi = 10.1002/gcc.2870010303 | s2cid = 2464453 }}
• {{cite journal | vauthors = Chen Q, Yang CY, Tsan JT, Xia Y, Ragab AH, Peiper SC, Carroll A, Baer R | title = Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia. | journal = J. Exp. Med. | volume = 172 | issue = 5 | pages = 1403–8 | year = 1990 | pmid = 2230650 | pmc = 2188666 | doi = 10.1084/jem.172.5.1403 }}
• {{cite journal | vauthors = Aplan PD, Begley CG, Bertness V, Nussmeier M, Ezquerra A, Coligan J, Kirsch IR | title = The SCL gene is formed from a transcriptionally complex locus. | journal = Mol. Cell. Biol. | volume = 10 | issue = 12 | pages = 6426–35 | year = 1991 | pmid = 2247063 | pmc = 362919 | doi = 10.1128/mcb.10.12.6426}}
• {{cite journal | vauthors = Chen Q, Cheng JT, Tasi LH, Schneider N, Buchanan G, Carroll A, Crist W, Ozanne B, Siciliano MJ, Baer R | title = The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein. | journal = EMBO J. | volume = 9 | issue = 2 | pages = 415–24 | year = 1990 | pmid = 2303035 | pmc = 551682 | doi = 10.1002/j.1460-2075.1990.tb08126.x}}
• {{cite journal | vauthors = Begley CG, Aplan PD, Denning SM, Haynes BF, Waldmann TA, Kirsch IR | title = The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif. | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 86 | issue = 24 | pages = 10128–32 | year = 1990 | pmid = 2602361 | pmc = 298658 | doi = 10.1073/pnas.86.24.10128 | doi-access = free }}
• {{cite journal | vauthors = Osada H, Grutz G, Axelson H, Forster A, Rabbitts TH | title = Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1. | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 92 | issue = 21 | pages = 9585–9 | year = 1995 | pmid = 7568177 | pmc = 40846 | doi = 10.1073/pnas.92.21.9585 | bibcode = 1995PNAS...92.9585O | doi-access = free }}
• {{cite journal | vauthors = Pulford K, Lecointe N, Leroy-Viard K, Jones M, Mathieu-Mahul D, Mason DY | title = Expression of TAL-1 proteins in human tissues. | journal = Blood | volume = 85 | issue = 3 | pages = 675–84 | year = 1995 | pmid = 7833471 | doi = 10.1182/blood.V85.3.675.bloodjournal853675| doi-access = free }}
• {{cite journal | vauthors = Wadman I, Li J, Bash RO, Forster A, Osada H, Rabbitts TH, Baer R | title = Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia. | journal = EMBO J. | volume = 13 | issue = 20 | pages = 4831–9 | year = 1994 | pmid = 7957052 | pmc = 395422 | doi = 10.1002/j.1460-2075.1994.tb06809.x}}
• {{cite journal | vauthors = Valge-Archer VE, Osada H, Warren AJ, Forster A, Li J, Baer R, Rabbitts TH | title = The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells. | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 91 | issue = 18 | pages = 8617–21 | year = 1994 | pmid = 8078932 | pmc = 44657 | doi = 10.1073/pnas.91.18.8617 | bibcode = 1994PNAS...91.8617V | doi-access = free }}
• {{cite journal | vauthors = Cross MA, Heyworth CM, Murrell AM, Bockamp EO, Dexter TM, Green AR | title = Expression of lineage restricted transcription factors precedes lineage specific differentiation in a multipotent haemopoietic progenitor cell line. | journal = Oncogene | volume = 9 | issue = 10 | pages = 3013–6 | year = 1994 | pmid = 8084606 }}
• {{cite journal | vauthors = Hsu HL, Wadman I, Baer R | title = Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells. | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 91 | issue = 8 | pages = 3181–5 | year = 1994 | pmid = 8159721 | pmc = 43539 | doi = 10.1073/pnas.91.8.3181 | bibcode = 1994PNAS...91.3181H | doi-access = free }}
• {{cite journal | vauthors = Hwang LY, Siegelman M, Davis L, Oppenheimer-Marks N, Baer R | title = Expression of the TAL1 proto-oncogene in cultured endothelial cells and blood vessels of the spleen. | journal = Oncogene | volume = 8 | issue = 11 | pages = 3043–6 | year = 1993 | pmid = 8414504 }}
• {{cite journal | vauthors = Cheng JT, Cobb MH, Baer R | title = Phosphorylation of the TAL1 oncoprotein by the extracellular-signal-regulated protein kinase ERK1. | journal = Mol. Cell. Biol. | volume = 13 | issue = 2 | pages = 801–8 | year = 1993 | pmid = 8423803 | pmc = 358963 | doi = 10.1128/mcb.13.2.801}}

{{refend}}

• {{MeshName|TAL1+protein,+human}}
• {{FactorBook|TAL1}}

{{Transcription factors|g1}}

Category:Transcription factors

{{gene-1-stub}}