GNA11

{{Short description|Protein-coding gene in the species Homo sapiens}}

Guanine nucleotide-binding protein subunit alpha-11 is a protein that in humans is encoded by the GNA11 gene.{{cite journal |vauthors=Wilkie TM, Gilbert DJ, Olsen AS, Chen XN, Amatruda TT, Korenberg JR, Trask BJ, de Jong P, Reed RR, Simon MI | title = Evolution of the mammalian G protein alpha subunit multigene family | journal = Nat Genet | volume = 1 | issue = 2 | pages = 85–91 |date=Jun 1993 | pmid = 1302014 | doi = 10.1038/ng0592-85 | s2cid = 31888533 |display-authors=etal| url = https://zenodo.org/record/1233383 }}{{cite web | title = Entrez Gene: GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2767}} Together with GNAQ (its paralogue), it functions as a Gq alpha subunit.[http://www.omim.org/entry/139313 139313 GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-11; GNA11] at OMIM. Retrieved January 1, 2015.

References

{{cite journal |vauthors=Raymond JR, Mukhin YV, Gelasco A |title=Multiplicity of mechanisms of serotonin receptor signal transduction. |journal=Pharmacol. Ther. |volume=92 |issue= 2–3 |pages= 179–212 |year= 2002 |pmid= 11916537 |doi=10.1016/S0163-7258(01)00169-3 |display-authors=etal}}
{{cite journal |vauthors=Jiang M, Pandey S, Tran VT, Fong HK |title=Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 9 |pages= 3907–11 |year= 1991 |pmid= 1902575 |doi=10.1073/pnas.88.9.3907 | pmc=51562 |bibcode=1991PNAS...88.3907J |doi-access=free }}
{{cite journal |vauthors=Thomas CP, Dunn MJ, Mattera R |title=Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways |journal=Biochem. J. |volume=312 |issue= 1|pages= 151–8 |year= 1996 |pmid= 7492305 |doi= 10.1042/bj3120151| pmc=1136238 }}
{{cite journal |vauthors=Offermanns S, Simon MI |title=G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C |journal=J. Biol. Chem. |volume=270 |issue= 25 |pages= 15175–80 |year= 1995 |pmid= 7797501 |doi=10.1074/jbc.270.25.15175 |doi-access=free }}
{{cite journal |vauthors=Stanners J, Kabouridis PS, McGuire KL, Tsoukas CD |title=Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling |journal=J. Biol. Chem. |volume=270 |issue= 51 |pages= 30635–42 |year= 1996 |pmid= 8530500 |doi=10.1074/jbc.270.51.30635 |doi-access=free }}
{{cite journal |vauthors=Laugwitz KL, Allgeier A, Offermanns S |title=The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 1 |pages= 116–20 |year= 1996 |pmid= 8552586 |doi=10.1073/pnas.93.1.116 | pmc=40189 |bibcode=1996PNAS...93..116L |display-authors=etal|doi-access=free }}
{{cite journal |vauthors=Launay JM, Birraux G, Bondoux D |title=Ras involvement in signal transduction by the serotonin 5-HT2B receptor |journal=J. Biol. Chem. |volume=271 |issue= 6 |pages= 3141–7 |year= 1996 |pmid= 8621713 |doi=10.1074/jbc.271.6.3141 |display-authors=etal|doi-access=free }}
{{cite journal |vauthors=Johnson GJ, Leis LA, Dunlop PC |title=Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences |journal=Biochem. J. |volume=318 |issue= 3|pages= 1023–31 |year= 1996 |pmid= 8836152 |doi= 10.1042/bj3181023| pmc=1217719 }}
{{cite journal |vauthors=Kinsella BT, O'Mahony DJ, Fitzgerald GA |title=The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha |journal=J. Pharmacol. Exp. Ther. |volume=281 |issue= 2 |pages= 957–64 |year= 1997 |pmid= 9152406 }}
{{cite journal |vauthors=Wise A, Parenti M, Milligan G |title=Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association |journal=FEBS Lett. |volume=407 |issue= 3 |pages= 257–60 |year= 1997 |pmid= 9175863 |doi=10.1016/S0014-5793(97)00300-1 |s2cid=85622146 }}
{{cite journal |vauthors=Carrasco MP, Asbóth G, Phaneuf S, López Bernal A |title=Activation of the prostaglandin FP receptor in human granulosa cells |journal=J. Reprod. Fertil. |volume=111 |issue= 2 |pages= 309–17 |year= 1998 |pmid= 9462300 |doi= 10.1530/jrf.0.1110309|doi-access=free }}
{{cite journal |vauthors=Qian A, Wang W, Sanborn BM |title=Evidence for the involvement of several intracellular domains in the coupling of oxytocin receptor to G alpha(q/11) |journal=Cell. Signal. |volume=10 |issue= 2 |pages= 101–5 |year= 1998 |pmid= 9481484 |doi=10.1016/S0898-6568(97)00097-1 }}
{{cite journal |vauthors=Dulin NO, Sorokin A, Reed E |title=RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11 |journal=Mol. Cell. Biol. |volume=19 |issue= 1 |pages= 714–23 |year= 1999 |pmid= 9858594 |doi= 10.1128/MCB.19.1.714| pmc=83928 |display-authors=etal}}
{{cite journal |vauthors=Hayes JS, Lawler OA, Walsh MT, Kinsella BT |title=The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling |journal=J. Biol. Chem. |volume=274 |issue= 34 |pages= 23707–18 |year= 1999 |pmid= 10446129 |doi=10.1074/jbc.274.34.23707 |doi-access=free }}
{{cite journal |vauthors=Brydon L, Roka F, Petit L |title=Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins |journal=Mol. Endocrinol. |volume=13 |issue= 12 |pages= 2025–38 |year= 2000 |pmid= 10598579 |doi=10.1210/mend.13.12.0390 |display-authors=etal|doi-access=free }}
{{cite journal |vauthors=Corbetta S, Mantovani G, Lania A |title=Calcium-sensing receptor expression and signalling in human parathyroid adenomas and primary hyperplasia |journal=Clin. Endocrinol. |volume=52 |issue= 3 |pages= 339–48 |year= 2000 |pmid= 10718832 |doi=10.1046/j.1365-2265.2000.00933.x |s2cid=39998840 |display-authors=etal}}
{{cite journal |vauthors=Shraga-Levine Z, Sokolovsky M |title=Functional coupling of G proteins to endothelin receptors is ligand and receptor subtype specific |journal=Cell. Mol. Neurobiol. |volume=20 |issue= 3 |pages= 305–17 |year= 2000 |pmid= 10789830 |doi=10.1023/A:1007010125316 |s2cid=21841332 |pmc=11537521 }}
{{cite journal |vauthors=AbdAlla S, Lother H, Abdel-tawab AM, Quitterer U |title=The angiotensin II AT2 receptor is an AT1 receptor antagonist |journal=J. Biol. Chem. |volume=276 |issue= 43 |pages= 39721–6 |year= 2001 |pmid= 11507095 |doi= 10.1074/jbc.M105253200 |doi-access= free }}

GNA11

See also

References

Further reading