GPR1

{{Short description|Protein-coding gene in the species Homo sapiens}}

G protein-coupled receptor 1, also known as GPR1, is a protein that in humans is encoded by the GPR1 gene.{{cite web | title = Entrez Gene: GPR1 G protein-coupled receptor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2825}}{{cite journal |vauthors=Marchese A, Docherty JM, Nguyen T, Heiber M, Cheng R, Heng HH, Tsui LC, Shi X, George SR, O'Dowd BF | title = Cloning of human genes encoding novel G protein-coupled receptors | journal = Genomics | volume = 23 | issue = 3 | pages = 609–18 |date=October 1994 | pmid = 7851889 | doi = 10.1006/geno.1994.1549 }}

GPR1 is a member of the G protein-coupled receptor family of transmembrane receptors. It functions as a receptor for chemerin.{{cite journal |vauthors=Barnea G, Strapps W, Herrada G, Berman Y, Ong J, Kloss B, Axel R, Lee KJ | title = The genetic design of signaling cascades to record receptor activation | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 105 | issue = 1 | pages = 64–9 |date=January 2008 | pmid = 18165312 | pmc = 2224232 | doi = 10.1073/pnas.0710487105 | doi-access = free }} Other receptors for chemerin include CMKLR1 and CCRL2.

References

{{cite journal | author=Shimizu N |title=An Orphan G Protein-Coupled Receptor, GPR1, Acts as a Coreceptor To Allow Replication of Human Immunodeficiency Virus Types 1 and 2 in Brain-Derived Cells |journal=J. Virol. |volume=73 |issue= 6 |pages= 5231–9 |year= 1999 |pmid= 10233994 |doi= 10.1128/JVI.73.6.5231-5239.1999| pmc=112576 |name-list-style=vanc| author2=Soda Y | author3=Kanbe K | display-authors=3 | last4=Liu | first4=HY | last5=Jinno | first5=A | last6=Kitamura | first6=T | last7=Hoshino | first7=H }}
{{cite journal | author=Tokizawa S |title=Infection of mesangial cells with HIV and SIV: identification of GPR1 as a coreceptor |journal=Kidney Int. |volume=58 |issue= 2 |pages= 607–17 |year= 2000 |pmid= 10916084 |doi= 10.1046/j.1523-1755.2000.00207.x |name-list-style=vanc| author2=Shimizu N | author3=Hui-Yu L | display-authors=3 | last4=Deyu | first4=Fang | last5=Haraguchi | first5=Yuji | last6=Oite | first6=Takashi | last7=Hoshino | first7=Hiroo | doi-access=free }}
{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
{{cite journal | author=Kang MK |title=Senescence-associated genes in normal human oral keratinocytes |journal=Exp. Cell Res. |volume=287 |issue= 2 |pages= 272–81 |year= 2003 |pmid= 12837283 |doi=10.1016/S0014-4827(03)00061-2 |name-list-style=vanc| author2=Kameta A | author3=Shin KH | display-authors=3 | last4=Baluda | first4=MA | last5=Kim | first5=HR | last6=Park | first6=NH }}
{{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-style=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
{{cite journal | author=Hillier LW |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4 |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 |name-list-style=vanc| author2=Graves TA | author3=Fulton RS | display-authors=3 | last4=Fulton | first4=Lucinda A. | last5=Pepin | first5=Kymberlie H. | last6=Minx | first6=Patrick | last7=Wagner-Mcpherson | first7=Caryn | last8=Layman | first8=Dan | last9=Wylie | first9=Kristine |bibcode=2005Natur.434..724H | doi-access=free }}
{{cite journal | author=Jinno-Oue A |title=The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 HIV-1 |journal=J. Biol. Chem. |volume=280 |issue= 35 |pages= 30924–34 |year= 2005 |pmid= 15919664 |doi= 10.1074/jbc.M500195200 |name-list-style=vanc| author2=Shimizu N | author3=Soda Y | display-authors=3 | last4=Tanaka | first4=A | last5=Ohtsuki | first5=T | last6=Kurosaki | first6=D | last7=Suzuki | first7=Y | last8=Hoshino | first8=H | doi-access=free }}
{{cite journal | author=Otsuki T |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 |name-list-style=vanc| author2=Ota T | author3=Nishikawa T | display-authors=3 | last4=Hayashi | first4=K | last5=Suzuki | first5=Y | last6=Yamamoto | first6=J | last7=Wakamatsu | first7=A | last8=Kimura | first8=K | last9=Sakamoto | first9=K | doi-access=free }}
{{cite journal | author=Kimura K |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 |name-list-style=vanc| author2=Wakamatsu A | author3=Suzuki Y | display-authors=3 | last4=Ota | first4=T | last5=Nishikawa | first5=T | last6=Yamashita | first6=R | last7=Yamamoto | first7=J | last8=Sekine | first8=M | last9=Tsuritani | first9=K }}

Category:G protein-coupled receptors

GPR1

References

Further reading