Graham Cooke
{{for|the Australian rugby union player|Graham Cooke (rugby union)}}
{{Infobox scientist
|name = Graham Cooke
|honorific_suffix = {{post-nominals|country=GBR|size=100%|sep=,|FRCP|FMedSci}}
|nationality = British
|birth_place = Hemel Hempstead, Hertfordshire, England
|education = Watford Boys Grammar School
|fields = Infectious diseases
|workplaces = Imperial College London
|alma_mater = St John's College, Cambridge
Worcester College, Oxford
University of KwaZulu-Natal
| thesis_title = Host genetic of susceptibility to tuberculosis (2003)
}}
Graham Cooke is a clinician scientist and NIHR Professor of Infectious Diseases at the Wright-Fleming Institute of Imperial College London.{{cite web|url=https://www.imperial.ac.uk/people/g.cooke|title=Home - Professor Graham Cooke|website=Imperial.ac.uk|accessdate=5 March 2019}} He is best known for his work on viral hepatitis, particularly hepatitis C.{{cite web|url=https://www.imperial.ac.uk/news/183606/hepatitis-research-pioneer-wins-prestigious-award/|title=Hepatitis C research pioneer wins prestigious award |website=Imperial.ac.uk|accessdate=5 March 2019}}{{cite web|url=http://www.infohep.org/Hepatitis-C-elimination-in-people-living-with-HIV-in-the-UK-is-feasible-by-2021-British-HIV-Association-says/page/3351119/|title=Hepatitis C elimination in people living with HIV in the UK is feasible by 2021, British HIV Association says|website=Infohep.org|accessdate=5 March 2019}}
Early life and education
Educated at Watford Grammar School for Boys, he studied natural sciences and medicine at University of Cambridge. Later he undertook his doctoral studies with Adrian V. S. Hill at the Wellcome Center for Human Genetics, studying human genetic variation and its role in susceptibility to tuberculosis.{{cite web |title=Human genetics and susceptibility to tuberculosis |url=https://solo.bodleian.ox.ac.uk/primo-explore/fulldisplay?docid=oxfaleph016023673&context=L&vid=SOLO&lang=en_US&search_scope=LSCOP_ALL&adaptor=Local%20Search%20Engine&tab=local&query=any,contains,cooke%20tuberculosis&offset=0 |accessdate=20 March 2019}}
Research and career
After specialist training in London, Cooke was based at the Africa Centre for Health and Population Studies, Mtubatuba (now AHRI) before moving to Imperial College.{{Cite web |title=Graham Cooke |url=https://www.globalhep.org/people/graham-cooke |access-date=2023-08-14 |website=Coalition for Global Hepatitis Elimination}} His work has focussed on HIV, tuberculosis and viral hepatitis. In 2016 he led publication of global estimates of viral hepatitis disease burden and has had a prominent role in efforts to raise the profile of viral hepatitis globally, leading the commission on viral hepatitis elimination in 2019. He has run randomised trials in the UK and Vietnam contributing insights into host-virus interactions and treatment outcomes.{{Cite journal |title=VIETNarms: a multi-arm trial of HCV treatment strategies in Vietnam |url=https://www.isrctn.com/ISRCTN61522291 |access-date=2023-08-14 |website=ISRCTN |doi=10.1186/isrctn61522291 |doi-access=free |last1=Cooke |first1=Graham |url-access=subscription }}
= COVID-19 =
During the COVID-19 pandemic, Cooke was an investigator on the REACT (Real-time Assessment of Community Transmission) programme, the largest study of consented individuals during the pandemic.{{Cite web |title=Find out about REACT |url=https://www.imperial.ac.uk/medicine/research-and-impact/groups/react-study/find-out-about-react/ |access-date=2023-08-14 |website=Imperial College London |language=en-GB}}{{Cite web |date=2020-09-11 |title=Largest COVID-19 testing study shows cases are rising across England |url=https://www.imperial.ac.uk/news/203873/largest-covid19-testing-study-shows-cases/ |access-date=2023-08-14 |website=Imperial News |language=en}} The programme made important contributions to government policy and informed decisions on relaxation of national restrictions and vaccine delivery.{{cite web|url=https://results2021.ref.ac.uk/impact/ee8ae278-b0a5-4b20-94c0-4858273fa796?page=1|website=results2021.ref.ac.uk|title= Real-time surveillance to improve situational awareness of COVID-19: the REACT study|accessdate=29 May 2023}}
With Chris Toumazou, he led the development of the COVIDnudge diagnostic,{{cite journal |last1=Gibani |first1=MM |last2=Toumazou |first2=C |last3=Sohbati |first3=M |last4=Sahoo |first4=R |last5=Karvela |first5=M |last6=Hon |first6=TK |last7=De Mateo |first7=S |last8=Burdett |first8=A |last9=Leung |first9=KYF |last10=Barnett |first10=J |last11=Orbeladze |first11=A |last12=Luan |first12=S |last13=Pournias |first13=S |last14=Sun |first14=J |last15=Flower |first15=B |last16=Bedzo-Nutakor |first16=J |last17=Amran |first17=M |last18=Quinlan |first18=R |last19=Skolimowska |first19=K |last20=Herrera |first20=C |last21=Rowan |first21=A |last22=Badhan |first22=A |last23=Klaber |first23=R |last24=Davies |first24=G |last25=Muir |first25=D |last26=Randell |first26=P |last27=Crook |first27=D |last28=Taylor |first28=GP |last29=Barclay |first29=W |last30=Mughal |first30=N |last31=Moore |first31=LSP |last32=Jeffery |first32=K |last33=Cooke |first33=GS |title=Assessing a novel, lab-free, point-of-care test for SARS-CoV-2 (CovidNudge): a diagnostic accuracy study. |journal=The Lancet. Microbe |date=November 2020 |volume=1 |issue=7 |pages=e300–e307 |doi=10.1016/S2666-5247(20)30121-X |pmid=32964211|pmc=7498257 |hdl=10044/1/82918 |hdl-access=free }} implemented in the NHS in 2020.{{Cite news |last=Boseley |first=Sarah |last2= |first2= |date=2020-09-17 |title=New UK Covid test is effective but won't impact numbers as hoped |language=en-GB |work=The Guardian |url=https://www.theguardian.com/world/2020/sep/17/new-uk-covid-test-is-effective-but-wont-impact-numbers-as-hoped |access-date=2023-08-14 |issn=0261-3077}}
= Other roles =
He has advocated for access to affordable medicines.{{Cite web |date=31 July 2019 |title=Initiative to increase access to expensive hepatitis drugs in poorer countries |url=https://imperialbrc.nihr.ac.uk/2019/07/31/voluntarylicense/ |access-date=2023-08-14 |website=NIHR Imperial Biomedical Research Centre |language=en-GB}} He became a member of the WHO committee for Selection and Use of Essential Medicines in 2015 and chairman in 2019.{{cite web|url=https://www.bbc.co.uk/programmes/p06pz10k|title=BBC World Service - World Update, New 'Trojan horse' antibiotic seems promising|website=BBC|accessdate=5 March 2019}} In 2021, he was appointed non-executive director and Deputy Chair of the Medicines and Healthcare products Regulatory Agency Board (MHRA).{{cite web|url=https://www.gov.uk/government/news/four-non-executive-directors-appointed-to-the-medicines-and-healthcare-products-regulatory-agency-board|website=gov.uk| title= Four Non-Executive Directors appointed to the Medicines and Healthcare products Regulatory Agency Board|accessdate=30 October 2021}}
Honours
He is a Fellow of the Royal College of Physicians (2012),{{Cite web |title=Dr Graham Cooke |url=https://www.imperial.nhs.uk/consultant-directory/graham-cooke |access-date=2023-08-14 |website=Imperial College Healthcare NHS Trust}} National Institute for Health and Care Research (NIHR) Research Professor (2017), Fellow of the Academy of Medical Sciences (2023).{{cite web|url=https://acmedsci.ac.uk/more/news/outstanding-biomedical-and-health-researchers-elected-to-academy-of-medical-sciences-fellowship|title=Outstanding biomedical and health researchers elected to Academy of Medical Sciences Fellowship|website=Academy of Medical Sciences|accessdate=14 July 2023}}
References
{{Reflist}}
External links
{{Scholia}}
- [https://www.imperial.ac.uk/news/255118/tackling-global-burden-hepatitis/ Tackling the global burden of hepatitis]. Interview with Graham Cooke.
{{Authority control}}
{{DEFAULTSORT:Cooke, Graham}}
Category:British infectious disease physicians
Category:Year of birth missing (living people)
Category:Academics of Imperial College London
Category:NIHR Research Professors
Category:Hepatitis researchers
Category:Alumni of St John's College, Cambridge
Category:Fellows of the Academy of Medical Sciences (United Kingdom)