HSPBP1
{{Short description|Protein-coding gene in the species Homo sapiens}}
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{{Infobox_gene}}
Hsp70-binding protein 1 is a protein that in humans is encoded by the HSPBP1 gene.{{cite journal | vauthors = Raynes DA, Guerriero V | title = Isolation and characterization of isoforms of HspBP1, inhibitors of Hsp70 | journal = Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | volume = 1490 | issue = 1–2 | pages = 203–7 | date = Jan 2000 | pmid = 10786638 | doi = 10.1016/s0167-4781(99)00238-9 }}{{cite journal | vauthors = Raynes DA, Guerriero V | title = Inhibition of Hsp70 ATPase activity and protein renaturation by a novel Hsp70-binding protein | journal = The Journal of Biological Chemistry | volume = 273 | issue = 49 | pages = 32883–8 | date = Dec 1998 | pmid = 9830037 | doi = 10.1074/jbc.273.49.32883 | doi-access = free }}{{cite web | title = Entrez Gene: HSPBP1 hsp70-interacting protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23640}}
Interactions
HSPBP1 has been shown to interact with HSPA8{{cite journal|author-link30=Huda Zoghbi | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R | s2cid = 4427026 }}{{cite journal | vauthors = Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE | title = A human protein-protein interaction network: a resource for annotating the proteome | journal = Cell | volume = 122 | issue = 6 | pages = 957–68 | date = Sep 2005 | pmid = 16169070 | doi = 10.1016/j.cell.2005.08.029 | hdl = 11858/00-001M-0000-0010-8592-0 | s2cid = 8235923 | hdl-access = free }} and HSPA4.{{cite journal | vauthors = Oh WK, Song J | title = Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation | journal = Molecules and Cells | volume = 16 | issue = 1 | pages = 84–91 | date = Aug 2003 | doi = 10.1016/S1016-8478(23)13770-8 | pmid = 14503850 | doi-access = free }}
References
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Further reading
{{refbegin | 2}}
- {{cite journal | vauthors = Zou J, Guo Y, Guettouche T, Smith DF, Voellmy R | title = Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1 | journal = Cell | volume = 94 | issue = 4 | pages = 471–80 | date = Aug 1998 | pmid = 9727490 | doi = 10.1016/S0092-8674(00)81588-3 | s2cid = 9234420 | doi-access = free }}
- {{cite journal | vauthors = Kabani M, McLellan C, Raynes DA, Guerriero V, Brodsky JL | title = HspBP1, a homologue of the yeast Fes1 and Sls1 proteins, is an Hsc70 nucleotide exchange factor | journal = FEBS Letters | volume = 531 | issue = 2 | pages = 339–42 | date = Nov 2002 | pmid = 12417338 | doi = 10.1016/S0014-5793(02)03570-6 | s2cid = 46738074 | doi-access = free }}
- {{cite journal | vauthors = McLellan CA, Raynes DA, Guerriero V | title = HspBP1, an Hsp70 cochaperone, has two structural domains and is capable of altering the conformation of the Hsp70 ATPase domain | journal = The Journal of Biological Chemistry | volume = 278 | issue = 21 | pages = 19017–22 | date = May 2003 | pmid = 12651857 | doi = 10.1074/jbc.M301109200 | doi-access = free }}
- {{cite journal | vauthors = Oh WK, Song J | title = Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation | journal = Molecules and Cells | volume = 16 | issue = 1 | pages = 84–91 | date = Aug 2003 | doi = 10.1016/S1016-8478(23)13770-8 | pmid = 14503850 | doi-access = free }}
- {{cite journal | vauthors = Lu QF, Bai M, Zhang HJ, Li JC, Xiao CF, Chen S, Wu TC | title = [Co-detection of P21, P53 and HSP70 and their possible role in diagnosis of polycyclic aromatic hydrocarbons (PAHs)-related lung cancer] | journal = Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi = Zhonghua Laodong Weisheng Zhiyebing Zazhi = Chinese Journal of Industrial Hygiene and Occupational Diseases | volume = 21 | issue = 5 | pages = 359–61 | date = Oct 2003 | pmid = 14761400 }}
- {{cite journal | vauthors = Alberti S, Böhse K, Arndt V, Schmitz A, Höhfeld J | title = The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator | journal = Molecular Biology of the Cell | volume = 15 | issue = 9 | pages = 4003–10 | date = Sep 2004 | pmid = 15215316 | pmc = 515335 | doi = 10.1091/mbc.E04-04-0293 }}
- {{cite journal | vauthors = Shomura Y, Dragovic Z, Chang HC, Tzvetkov N, Young JC, Brodsky JL, Guerriero V, Hartl FU, Bracher A | title = Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange | journal = Molecular Cell | volume = 17 | issue = 3 | pages = 367–79 | date = Feb 2005 | pmid = 15694338 | doi = 10.1016/j.molcel.2004.12.023 | doi-access = free }}
- {{cite journal | vauthors = Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE | title = A human protein-protein interaction network: a resource for annotating the proteome | journal = Cell | volume = 122 | issue = 6 | pages = 957–68 | date = Sep 2005 | pmid = 16169070 | doi = 10.1016/j.cell.2005.08.029 | hdl = 11858/00-001M-0000-0010-8592-0 | s2cid = 8235923 | hdl-access = free }}
- {{cite journal | vauthors = Dai Q, Qian SB, Li HH, McDonough H, Borchers C, Huang D, Takayama S, Younger JM, Ren HY, Cyr DM, Patterson C | title = Regulation of the cytoplasmic quality control protein degradation pathway by BAG2 | journal = The Journal of Biological Chemistry | volume = 280 | issue = 46 | pages = 38673–81 | date = Nov 2005 | pmid = 16169850 | doi = 10.1074/jbc.M507986200 | doi-access = free }}
- {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R | s2cid = 4427026 }}
- {{cite journal | vauthors = Gottwald E, Herschbach M, Lahni B, Miesfeld RL, Kunz S, Raynes DA, Guerriero V | title = Expression of the cochaperone HspBP1 is not coordinately regulated with Hsp70 expression | journal = Cell Biology International | volume = 30 | issue = 6 | pages = 553–8 | date = Jun 2006 | pmid = 16677834 | doi = 10.1016/j.cellbi.2006.03.005 | s2cid = 2046710 }}
- {{cite journal | vauthors = Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY | title = A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration | journal = Cell | volume = 125 | issue = 4 | pages = 801–14 | date = May 2006 | pmid = 16713569 | doi = 10.1016/j.cell.2006.03.032 | s2cid = 13709685 | doi-access = free }}
- {{cite journal | vauthors = Bivik C, Rosdahl I, Ollinger K | title = Hsp70 protects against UVB induced apoptosis by preventing release of cathepsins and cytochrome c in human melanocytes | journal = Carcinogenesis | volume = 28 | issue = 3 | pages = 537–44 | date = Mar 2007 | pmid = 16950797 | doi = 10.1093/carcin/bgl152 | doi-access = free }}
- {{cite journal | vauthors = Swayne LA, Braun JE | title = Aggregate-centered redistribution of proteins by mutant huntingtin | journal = Biochemical and Biophysical Research Communications | volume = 354 | issue = 1 | pages = 39–44 | date = Mar 2007 | pmid = 17208201 | doi = 10.1016/j.bbrc.2006.12.129 }}
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{{PDB Gallery|geneid=23640}}
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