HSPA4

HSPA4 has been shown to interact with:

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• APAF1{{cite journal | vauthors = Saleh A, Srinivasula SM, Balkir L, Robbins PD, Alnemri ES | title = Negative regulation of the Apaf-1 apoptosome by Hsp70 | journal = Nature Cell Biology | volume = 2 | issue = 8 | pages = 476–83 | date = Aug 2000 | pmid = 10934467 | doi = 10.1038/35019510 | s2cid = 20374981 }}
• DNAJB1,
• HDAC1,{{cite journal | vauthors = Johnson CA, White DA, Lavender JS, O'Neill LP, Turner BM | title = Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 11 | pages = 9590–7 | date = Mar 2002 | pmid = 11777905 | doi = 10.1074/jbc.M107942200 | doi-access = free }}
• HSF1,{{cite journal | vauthors = Nair SC, Toran EJ, Rimerman RA, Hjermstad S, Smithgall TE, Smith DF | title = A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor | journal = Cell Stress & Chaperones | volume = 1 | issue = 4 | pages = 237–50 | date = Dec 1996 | doi = 10.1379/1466-1268(1996)001<0237:apomci>2.3.co;2 | doi-broken-date = 2024-11-02 | pmid = 9222609 | pmc = 376461 }}{{cite journal | vauthors = Abravaya K, Myers MP, Murphy SP, Morimoto RI | title = The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression | journal = Genes & Development | volume = 6 | issue = 7 | pages = 1153–64 | date = Jul 1992 | pmid = 1628823 | doi = 10.1101/gad.6.7.1153| doi-access = free }}
• HSPBP1,
• Histone deacetylase 2,
• NAD(P)H dehydrogenase (quinone 1),{{cite journal | vauthors = Anwar A, Siegel D, Kepa JK, Ross D | title = Interaction of the molecular chaperone Hsp70 with human NAD(P)H:quinone oxidoreductase 1 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 16 | pages = 14060–7 | date = Apr 2002 | pmid = 11821413 | doi = 10.1074/jbc.M111576200 | doi-access = free }}
• STUB1,{{cite journal | vauthors = Ballinger CA, Connell P, Wu Y, Hu Z, Thompson LJ, Yin LY, Patterson C | title = Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions | journal = Molecular and Cellular Biology | volume = 19 | issue = 6 | pages = 4535–45 | date = Jun 1999 | pmid = 10330192 | pmc = 104411 | doi = 10.1128/mcb.19.6.4535}} and
• TTC1.{{cite journal | vauthors = Oh WK, Song J | title = Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation | journal = Molecules and Cells | volume = 16 | issue = 1 | pages = 84–91 | date = Aug 2003 | doi = 10.1016/S1016-8478(23)13770-8 | pmid = 14503850 | doi-access = free }}

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{{Reflist|33em}}

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• {{cite journal | vauthors = Abravaya K, Myers MP, Murphy SP, Morimoto RI | title = The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression | journal = Genes & Development | volume = 6 | issue = 7 | pages = 1153–64 | date = Jul 1992 | pmid = 1628823 | doi = 10.1101/gad.6.7.1153 | doi-access = free }}
• {{cite journal | vauthors = Liao J, Lowthert LA, Ghori N, Omary MB | title = The 70-kDa heat shock proteins associate with glandular intermediate filaments in an ATP-dependent manner | journal = The Journal of Biological Chemistry | volume = 270 | issue = 2 | pages = 915–22 | date = Jan 1995 | pmid = 7529764 | doi = 10.1074/jbc.270.2.915 | doi-access = free }}
• {{cite journal | vauthors = Furlini G, Vignoli M, Re MC, Gibellini D, Ramazzotti E, Zauli G, La Placa M | title = Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein | journal = The Journal of General Virology | volume = 75 | issue = 1 | pages = 193–9 | date = Jan 1994 | pmid = 7906708 | doi = 10.1099/0022-1317-75-1-193 | doi-access = free }}
• {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Research | volume = 6 | issue = 9 | pages = 791–806 | date = Sep 1996 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 | doi-access = free }}
• {{cite journal | vauthors = Schulte AM, Fischer S, Sachse GE, Häfner S, Stelck S, Gassen HG | title = Identification and characterization of a novel hsc70-like gene in the human lung tumor cell line HS24 | journal = DNA and Cell Biology | volume = 16 | issue = 3 | pages = 257–68 | date = Mar 1997 | pmid = 9115634 | doi = 10.1089/dna.1997.16.257 }}
• {{cite journal | vauthors = Kaneko Y, Kimura T, Kishishita M, Noda Y, Fujita J | title = Cloning of apg-2 encoding a novel member of heat shock protein 110 family | journal = Gene | volume = 189 | issue = 1 | pages = 19–24 | date = Apr 1997 | pmid = 9161406 | doi = 10.1016/S0378-1119(96)00807-4 }}
• {{cite journal | vauthors = Bruner KL, Derfoul A, Robertson NM, Guerriero G, Fernandes-Alnemri T, Alnemri ES, Litwack G | title = The unliganded mineralocorticoid receptor is associated with heat shock proteins 70 and 90 and the immunophilin FKBP-52 | journal = Receptors & Signal Transduction | volume = 7 | issue = 2 | pages = 85–98 | year = 1998 | pmid = 9392437 }}
• {{cite journal | vauthors = Satyal SH, Chen D, Fox SG, Kramer JM, Morimoto RI | title = Negative regulation of the heat shock transcriptional response by HSBP1 | journal = Genes & Development | volume = 12 | issue = 13 | pages = 1962–74 | date = Jul 1998 | pmid = 9649501 | pmc = 316975 | doi = 10.1101/gad.12.13.1962 }}
• {{cite journal | vauthors = Naylor DJ, Stines AP, Hoogenraad NJ, Høj PB | title = Evidence for the existence of distinct mammalian cytosolic, microsomal, and two mitochondrial GrpE-like proteins, the Co-chaperones of specific Hsp70 members | journal = The Journal of Biological Chemistry | volume = 273 | issue = 33 | pages = 21169–77 | date = Aug 1998 | pmid = 9694873 | doi = 10.1074/jbc.273.33.21169 | doi-access = free }}
• {{cite journal | vauthors = Melville MW, Tan SL, Wambach M, Song J, Morimoto RI, Katze MG | title = The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity | journal = The Journal of Biological Chemistry | volume = 274 | issue = 6 | pages = 3797–803 | date = Feb 1999 | pmid = 9920933 | doi = 10.1074/jbc.274.6.3797 | doi-access = free }}
• {{cite journal | vauthors = Ballinger CA, Connell P, Wu Y, Hu Z, Thompson LJ, Yin LY, Patterson C | title = Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions | journal = Molecular and Cellular Biology | volume = 19 | issue = 6 | pages = 4535–45 | date = Jun 1999 | pmid = 10330192 | pmc = 104411 | doi = 10.1128/mcb.19.6.4535}}
• {{cite journal | vauthors = Liu H, Vuyyuru VB, Pham CD, Yang Y, Singh B | title = Evidence of an interaction between Mos and Hsp70: a role of the Mos residue serine 3 in mediating Hsp70 association | journal = Oncogene | volume = 18 | issue = 23 | pages = 3461–70 | date = Jun 1999 | pmid = 10376524 | doi = 10.1038/sj.onc.1202699 | doi-access = free }}
• {{cite journal | vauthors = Nonoguchi K, Itoh K, Xue JH, Tokuchi H, Nishiyama H, Kaneko Y, Tatsumi K, Okuno H, Tomiwa K, Fujita J | title = Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes | journal = Gene | volume = 237 | issue = 1 | pages = 21–8 | date = Sep 1999 | pmid = 10524232 | doi = 10.1016/S0378-1119(99)00325-X }}
• {{cite journal | vauthors = O'Keeffe B, Fong Y, Chen D, Zhou S, Zhou Q | title = Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription | journal = The Journal of Biological Chemistry | volume = 275 | issue = 1 | pages = 279–87 | date = Jan 2000 | pmid = 10617616 | doi = 10.1074/jbc.275.1.279 | doi-access = free }}
• {{cite journal | vauthors = Agostini I, Popov S, Li J, Dubrovsky L, Hao T, Bukrinsky M | title = Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex | journal = Experimental Cell Research | volume = 259 | issue = 2 | pages = 398–403 | date = Sep 2000 | pmid = 10964507 | doi = 10.1006/excr.2000.4992 }}
• {{cite journal | vauthors = Kim M, Jiang LH, Wilson HL, North RA, Surprenant A | title = Proteomic and functional evidence for a P2X7 receptor signalling complex | journal = The EMBO Journal | volume = 20 | issue = 22 | pages = 6347–58 | date = Nov 2001 | pmid = 11707406 | pmc = 125721 | doi = 10.1093/emboj/20.22.6347 }}
• {{cite journal | vauthors = Johnson CA, White DA, Lavender JS, O'Neill LP, Turner BM | title = Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 11 | pages = 9590–7 | date = Mar 2002 | pmid = 11777905 | doi = 10.1074/jbc.M107942200 | doi-access = free }}
• {{cite journal | vauthors = Gurer C, Cimarelli A, Luban J | title = Specific incorporation of heat shock protein 70 family members into primate lentiviral virions | journal = Journal of Virology | volume = 76 | issue = 9 | pages = 4666–70 | date = May 2002 | pmid = 11932435 | pmc = 155079 | doi = 10.1128/JVI.76.9.4666-4670.2002 }}
• {{cite journal | vauthors = Freeman BC, Yamamoto KR | title = Disassembly of transcriptional regulatory complexes by molecular chaperones | journal = Science | volume = 296 | issue = 5576 | pages = 2232–5 | date = Jun 2002 | pmid = 12077419 | doi = 10.1126/science.1073051 | s2cid = 8844179 }}

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• {{MeshName|HSPA4+protein,+human}}

{{Chaperones}}

Category:Heat shock proteins