Haplogroup Q-M25
{{short description|Subgroup of a human Y-DNA haplogroup}}
{{Infobox haplogroup
| name = Q-M25
| map =
| origin-date = 24,300 [95% CI 22,100 <-> 26,700] years before present (YFull v6.02)
| TMRCA = 16,400 [95% CI 14,900 <-> 18,000] years before present (YFull v6.02[http://www.yfull.com/tree/Q-M25/ YFull] Haplogroup YTree v6.02 at 02 April 2018)
| origin-place = Central Asia
| ancestor = Q-F1096(F1215)
| descendants =
| mutations = M25
}}
Haplogroup Q-M25, also known as Q1a1b is a subclade or branch of human Y-DNA haplogroup Q-F1096 (Q1a1), which is, in turn, a subclade of Q-MEH2 (Q1a). In human genetics, each Y-DNA haplogroup constitutes a biological paternal lineages back to a shared common male ancestor.
Distribution
Q-M25 has descendants in modern populations across all of Eurasia. Only one detailed study on the Y-DNA on Turkmens from Turkmenistan has taken place.{{cite journal |last1=Wells |first1=R. Spencer |title=The Eurasian Heartland: A continental perspective on Y-chromosome diversity |journal=Proc Natl Acad Sci U S A |date=18 August 2001 |volume=98 |issue=18 |pages=Page 2, Table 1 |pmid=11526236 |pmc=56946 |doi=10.1073/pnas.171305098 |bibcode=2001PNAS...9810244W |doi-access=free }} Haplogroup Q is found in minority Turkmen tribes living in Afghanistan at percentages of about 32%,J D Cristofaro et al., 2013, "Afghan Hindu Kush: Where Eurasian Sub-Continent Gene Flows Converge", http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0076748 and another study found that 42.6% of Iranian Turkmens have haplogroup Q-M25 (also known as Q1a1b).
=The Americas=
Q-M25 has not been detected in pre-Columbian populations in the Americas.
=Asia=
Q-M25 has been detected in the Northeast of East Asia, in South Asia, and across Central Asia.{{cite journal | doi=10.1038/jhg.2011.64 | title=Ancient links between Siberians and Native Americans revealed by subtyping the Y chromosome haplogroup Q1a | year=2011 | last1=Malyarchuk | first1=Boris | last2=Derenko | first2=Miroslava | last3=Denisova | first3=Galina | last4=Maksimov | first4=Arkady | last5=Wozniak | first5=Marcin | last6=Grzybowski | first6=Tomasz | last7=Dambueva | first7=Irina | last8=Zakharov | first8=Ilya | journal=Journal of Human Genetics | volume=56 | issue=8 | pages=583–8 | pmid=21677663| doi-access=free }}{{cite journal |doi = 10.1038/81685 |year = 2000 |last1 = Underhill |first1 = Peter A. |last2 = Shen |first2 = Peidong |last3 = Lin |first3 = Alice A. |last4 = Jin |first4 = Li |last5 = Passarino |first5 = Giuseppe |last6 = Yang |first6 = Wei H. |last7 = Kauffman |first7 = Erin |last8 = Bonné-Tamir |first8 = Batsheva |last9 = Bertranpetit |first9 = Jaume |last10 = Francalacci |first10 = Paolo |last11 = Ibrahim |first11 = Muntaser |last12 = Jenkins |first12 = Trefor |last13 = Kidd |first13 = Judith R. |last14 = Mehdi |first14 = S. Qasim |last15 = Seielstad |first15 = Mark T. |last16 = Wells |first16 = R. Spencer |last17 = Piazza |first17 = Alberto |last18 = Davis |first18 = Ronald W. |last19 = Feldman |first19 = Marcus W. |last20 = Cavalli-Sforza |first20 = L. Luca |last21 = Oefner |first21 = Peter. J. |journal = Nature Genetics |volume = 26 |issue = 3 |pages = 358–61 |pmid = 11062480 |title = Y chromosome sequence variation and the history of human populations|s2cid = 12893406 |display-authors = 8 }}{{cite journal | doi = 10.1093/molbev/msq247 | title = Extended Y Chromosome Investigation Suggests Postglacial Migrations of Modern Humans into 42.6East Asia via the Northern Route | year = 2010 | last1 = Zhong | first1 = H. | last2 = Shi | first2 = H. | last3 = Qi | first3 = X.-B. | last4 = Duan | first4 = Z.-Y. | last5 = Tan | first5 = P.-P. | last6 = Jin | first6 = L. | last7 = Su | first7 = B. | last8 = Ma | first8 = R. Z. | journal = Molecular Biology and Evolution | volume = 28 | pages = 717–27 | pmid = 20837606 | issue = 1| doi-access = free }} Though present at low frequencies, it may be one of the more widely distributed branches of Q-M242 in Asia.
class="wikitable"
! Population | Sampling Location | Paper | N | Percentage | SNP Tested |
Turkmen | Golestan, Iran | Grugni 2012 | 29/68 | ~42.6% | M25 & M143 |
Turkmen | Jawzjan, Afghanistan | Di Cristofaro 2013 | 23/74 | ~31.1% | M25 & M346/ (cf)Q1a3(currently Q1a2)=2/74 (Q total=33.8%) |
Mixed | Central Asia & Siberia | Underhill 2000 | 6/184 | ~3.26% | M25 & M143 |
Kalmyk | Malyarchuk 2011 | 1/60 | ~1.70% | M25 | |
Han | Shanxi | Zhong 2010 | 1/56 | ~1.79% | M25 |
Uyghur | Xinjiang | Zhong 2010 | 1/71 | ~1.41% | M25 |
Uyghur | Xinjiang | Zhong 2010 | 1/50 | ~2.00% | M25 |
Uzbek | Jawzjan, Afghanistan | Di Cristofaro 2013 | 1/94 | ~1.06% | M25 |
Mongol | Mongolia | Di Cristofaro 2013 | 1/160 | ~0.63% | M25 |
==West Asia==
The frequency of Q-M25 varies greatly across West Asia. An extreme peak is seen in the Turkmen of Golestan.{{cite journal |doi = 10.1371/journal.pone.0041252 |title = Ancient Migratory Events in the Middle East: New Clues from the Y-Chromosome Variation of Modern Iranians |year = 2012 |editor1-last = Kivisild |editor1-first = Toomas |last1 = Grugni |first1 = Viola |last2 = Battaglia |first2 = Vincenza |last3 = Hooshiar Kashani |first3 = Baharak |last4 = Parolo |first4 = Silvia |last5 = Al-Zahery |first5 = Nadia |last6 = Achilli |first6 = Alessandro |last7 = Olivieri |first7 = Anna |last8 = Gandini |first8 = Francesca |last9 = Houshmand |first9 = Massoud |last10 = Sanati |first10 = M. H. |last11 = Torroni |first11 = A |last12 = Semino |first12 = O |journal = PLOS ONE |volume = 7 |issue = 7 |pages = e41252 |pmid = 22815981 |pmc = 3399854|bibcode = 2012PLoSO...741252G |display-authors = 8 |doi-access = free }} Across the whole of Iran it varies from over 9 percent of the population in the north to only 2 to 3 percent of the population in the south.{{cite journal |vauthors=Regueiro M, Cadenas AM, Gayden T, Underhill PA, Herrera RJ |title=Iran: tricontinental nexus for Y-chromosome driven migration |journal=Hum. Hered. |volume=61 |issue=3 |pages=132–43 |year=2006 |pmid=16770078 |doi=10.1159/000093774 |s2cid=7017701 }} The frequency of Q-M25 drops to only about 1 percent of the population of Lebanon's Muslims, and it is absent from the non-Muslim population there.{{cite journal | doi = 10.1016/j.ajhg.2008.01.020 | last1 = Zalloua | first1 = Pierre A. |name-list-style=vanc | last2 = Xue | first2 = Y| year = 2008 | last3 = Khalife | first3 = J | last4 = Makhoul | first4 = N | last5 = Debiane | first5 = L | last6 = Platt | first6 = DE | last7 = Royyuru | first7 = AK | last8 = Herrera | first8 = RJ | last9 = Hernanz | first9 = DF| last10 = Blue-Smith | first10 = Jason | last11 = Wells | first11 = R. Spencer | last12 = Comas | first12 = David | last13 = Bertranpetit | first13 = Jaume | last14 = Tyler-Smith | first14 = Chris | last15 = Genographic | first15 = Consortium | title = Y-Chromosomal Diversity in Lebanon Is Structured by Recent Historical Events | journal = American Journal of Human Genetics | volume = 82 | issue = 4| pages = 873–882 | pmid = 18374297 | pmc = 2427286 | display-authors = 8 }} However, its presence in the Marsh Arabs(related to Sumer) of Iraq hints that Q-M25's West Asian history extends beyond a single localized recent founder.{{cite journal | doi = 10.1186/1471-2148-11-288 | title = In search of the genetic footprints of Sumerians: A survey of Y-chromosome and mtDNA variation in the Marsh Arabs of Iraq | year = 2011 | last1 = Al-Zahery | first1 = Nadia | last2 = Pala | first2 = Maria | last3 = Battaglia | first3 = Vincenza | last4 = Grugni | first4 = Viola | last5 = Hamod | first5 = Mohammed A | last6 = Kashani | first6 = Baharak | last7 = Olivieri | first7 = Anna | last8 = Torroni | first8 = Antonio | last9 = Santachiara-Benerecetti | first9 = Augusta S | last10 = Semino | first10 = Ornella | journal = BMC Evolutionary Biology | volume = 11 | issue = 1 | pages = 288 | pmid = 21970613 | pmc = 3215667 | bibcode = 2011BMCEE..11..288A | doi-access = free }}
class="wikitable"
! Population | Sampling Location | Paper | N | Percentage | SNP Tested |
Marsh Arabs | Al-Zahery 2011 | 1/143 | ~0.70% | M25/ (cf)Q1b-M378=2.1% | |
Iraqis | Al-Zahery 2011 | 0/154 | ~0.00% | M25/ (cf)Q1b-M378=1.9% | |
Iranians | Iran (North) | Regueiro 2006 | 3/33 | ~9.09% | M25 |
Iranians | Mazandaran | Di Cristofaro 2013 | 1/13 | ~7.69% | M25 |
Iranians | Iran (South) | Regueiro 2006 | 3/117 | ~2.56% | M25 |
Iranians | Esfahan | Di Cristofaro 2013 | 1/42 | ~2.38% | M25 |
Azeris | Iran (Azeri) | Grugni 2012 | 1/63 | ~1.60% | M25 |
Turkmens | Golestan | Grugni 2012 | 29/68 | ~42.6% | M25 |
Lebanese (Non-Muslim) | Lebanon | Zalloua 2008 | 0/482 | ~0.00% | M25 |
Lebanese (Muslim) | Lebanon | Zalloua 2008 | 4/432 | ~0.93% | M25 |
=Europe=
Q-M25 is present across modern Turkey{{cite journal |vauthors=Cinnioğlu C, King R, Kivisild T, etal |title=Excavating Y-chromosome haplotype strata in Anatolia |journal=Hum. Genet. |volume=114 |issue=2 |pages=127–48 |date=January 2004 |pmid=14586639 |doi=10.1007/s00439-003-1031-4 |s2cid=10763736 }} and in Eastern Europe.
class="wikitable"
! Population | Paper | N | Percentage | SNP Tested | |
East Anatolia | Cinnioglu 2004 | 1/82 | ~1.20% | M25 |
Associated SNP's
Haplogroup Q-M25 is defined by the presence of the M25 Single Nucleotide Polymorphism (SNP) as well as the M143, L714, and L716 SNPs.
Phylogenetic Tree
This is Thomas Krahn at the Genomic Research Center's Draft tree [https://web.archive.org/web/20130526161518/http://ytree.ftdna.com/index.php?name=Draft&parent=8104789 Proposed Tree] for haplogroup Q-M25.
- Q-M25 M25, M143, L714, L716
- Q-L712 L712
- Q-L713 L697.2, L713, L715, M365.3
See also
=Y-DNA Q-M242 Subclades=
= Y-DNA Backbone Tree =
{{Y-DNA}}
References
External links
- [http://www.familytreedna.com/public/yDNA_Q/ The Y-DNA Haplogroup Q Project]
{{DEFAULTSORT:Haplogroup Q-M25 (Y-Dna)}}