Haplogroup Q-M25

{{short description|Subgroup of a human Y-DNA haplogroup}}

{{Infobox haplogroup

| name = Q-M25

| map =

| origin-date = 24,300 [95% CI 22,100 <-> 26,700] years before present (YFull v6.02)

| TMRCA = 16,400 [95% CI 14,900 <-> 18,000] years before present (YFull v6.02[http://www.yfull.com/tree/Q-M25/ YFull] Haplogroup YTree v6.02 at 02 April 2018)

| origin-place = Central Asia

| ancestor = Q-F1096(F1215)

| descendants =

| mutations = M25

}}

Haplogroup Q-M25, also known as Q1a1b is a subclade or branch of human Y-DNA haplogroup Q-F1096 (Q1a1), which is, in turn, a subclade of Q-MEH2 (Q1a). In human genetics, each Y-DNA haplogroup constitutes a biological paternal lineages back to a shared common male ancestor.

Distribution

Q-M25 has descendants in modern populations across all of Eurasia. Only one detailed study on the Y-DNA on Turkmens from Turkmenistan has taken place.{{cite journal |last1=Wells |first1=R. Spencer |title=The Eurasian Heartland: A continental perspective on Y-chromosome diversity |journal=Proc Natl Acad Sci U S A |date=18 August 2001 |volume=98 |issue=18 |pages=Page 2, Table 1 |pmid=11526236 |pmc=56946 |doi=10.1073/pnas.171305098 |bibcode=2001PNAS...9810244W |doi-access=free }} Haplogroup Q is found in minority Turkmen tribes living in Afghanistan at percentages of about 32%,J D Cristofaro et al., 2013, "Afghan Hindu Kush: Where Eurasian Sub-Continent Gene Flows Converge", http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0076748 and another study found that 42.6% of Iranian Turkmens have haplogroup Q-M25 (also known as Q1a1b).

=The Americas=

Q-M25 has not been detected in pre-Columbian populations in the Americas.

=Asia=

Q-M25 has been detected in the Northeast of East Asia, in South Asia, and across Central Asia.{{cite journal | doi=10.1038/jhg.2011.64 | title=Ancient links between Siberians and Native Americans revealed by subtyping the Y chromosome haplogroup Q1a | year=2011 | last1=Malyarchuk | first1=Boris | last2=Derenko | first2=Miroslava | last3=Denisova | first3=Galina | last4=Maksimov | first4=Arkady | last5=Wozniak | first5=Marcin | last6=Grzybowski | first6=Tomasz | last7=Dambueva | first7=Irina | last8=Zakharov | first8=Ilya | journal=Journal of Human Genetics | volume=56 | issue=8 | pages=583–8 | pmid=21677663| doi-access=free }}{{cite journal |doi = 10.1038/81685 |year = 2000 |last1 = Underhill |first1 = Peter A. |last2 = Shen |first2 = Peidong |last3 = Lin |first3 = Alice A. |last4 = Jin |first4 = Li |last5 = Passarino |first5 = Giuseppe |last6 = Yang |first6 = Wei H. |last7 = Kauffman |first7 = Erin |last8 = Bonné-Tamir |first8 = Batsheva |last9 = Bertranpetit |first9 = Jaume |last10 = Francalacci |first10 = Paolo |last11 = Ibrahim |first11 = Muntaser |last12 = Jenkins |first12 = Trefor |last13 = Kidd |first13 = Judith R. |last14 = Mehdi |first14 = S. Qasim |last15 = Seielstad |first15 = Mark T. |last16 = Wells |first16 = R. Spencer |last17 = Piazza |first17 = Alberto |last18 = Davis |first18 = Ronald W. |last19 = Feldman |first19 = Marcus W. |last20 = Cavalli-Sforza |first20 = L. Luca |last21 = Oefner |first21 = Peter. J. |journal = Nature Genetics |volume = 26 |issue = 3 |pages = 358–61 |pmid = 11062480 |title = Y chromosome sequence variation and the history of human populations|s2cid = 12893406 |display-authors = 8 }}{{cite journal | doi = 10.1093/molbev/msq247 | title = Extended Y Chromosome Investigation Suggests Postglacial Migrations of Modern Humans into 42.6East Asia via the Northern Route | year = 2010 | last1 = Zhong | first1 = H. | last2 = Shi | first2 = H. | last3 = Qi | first3 = X.-B. | last4 = Duan | first4 = Z.-Y. | last5 = Tan | first5 = P.-P. | last6 = Jin | first6 = L. | last7 = Su | first7 = B. | last8 = Ma | first8 = R. Z. | journal = Molecular Biology and Evolution | volume = 28 | pages = 717–27 | pmid = 20837606 | issue = 1| doi-access = free }} Though present at low frequencies, it may be one of the more widely distributed branches of Q-M242 in Asia.

class="wikitable"

! Population

Sampling LocationPaperNPercentageSNP Tested
TurkmenGolestan, IranGrugni 201229/68~42.6%M25 & M143
TurkmenJawzjan, AfghanistanDi Cristofaro 201323/74~31.1%M25 & M346/ (cf)Q1a3(currently Q1a2)=2/74 (Q total=33.8%)
MixedCentral Asia & SiberiaUnderhill 20006/184~3.26%M25 & M143
KalmykMalyarchuk 20111/60~1.70%M25
HanShanxiZhong 20101/56~1.79%M25
UyghurXinjiangZhong 20101/71~1.41%M25
UyghurXinjiangZhong 20101/50~2.00%M25
UzbekJawzjan, AfghanistanDi Cristofaro 20131/94~1.06%M25
MongolMongoliaDi Cristofaro 20131/160~0.63%M25

==West Asia==

The frequency of Q-M25 varies greatly across West Asia. An extreme peak is seen in the Turkmen of Golestan.{{cite journal |doi = 10.1371/journal.pone.0041252 |title = Ancient Migratory Events in the Middle East: New Clues from the Y-Chromosome Variation of Modern Iranians |year = 2012 |editor1-last = Kivisild |editor1-first = Toomas |last1 = Grugni |first1 = Viola |last2 = Battaglia |first2 = Vincenza |last3 = Hooshiar Kashani |first3 = Baharak |last4 = Parolo |first4 = Silvia |last5 = Al-Zahery |first5 = Nadia |last6 = Achilli |first6 = Alessandro |last7 = Olivieri |first7 = Anna |last8 = Gandini |first8 = Francesca |last9 = Houshmand |first9 = Massoud |last10 = Sanati |first10 = M. H. |last11 = Torroni |first11 = A |last12 = Semino |first12 = O |journal = PLOS ONE |volume = 7 |issue = 7 |pages = e41252 |pmid = 22815981 |pmc = 3399854|bibcode = 2012PLoSO...741252G |display-authors = 8 |doi-access = free }} Across the whole of Iran it varies from over 9 percent of the population in the north to only 2 to 3 percent of the population in the south.{{cite journal |vauthors=Regueiro M, Cadenas AM, Gayden T, Underhill PA, Herrera RJ |title=Iran: tricontinental nexus for Y-chromosome driven migration |journal=Hum. Hered. |volume=61 |issue=3 |pages=132–43 |year=2006 |pmid=16770078 |doi=10.1159/000093774 |s2cid=7017701 }} The frequency of Q-M25 drops to only about 1 percent of the population of Lebanon's Muslims, and it is absent from the non-Muslim population there.{{cite journal | doi = 10.1016/j.ajhg.2008.01.020 | last1 = Zalloua | first1 = Pierre A. |name-list-style=vanc | last2 = Xue | first2 = Y| year = 2008 | last3 = Khalife | first3 = J | last4 = Makhoul | first4 = N | last5 = Debiane | first5 = L | last6 = Platt | first6 = DE | last7 = Royyuru | first7 = AK | last8 = Herrera | first8 = RJ | last9 = Hernanz | first9 = DF| last10 = Blue-Smith | first10 = Jason | last11 = Wells | first11 = R. Spencer | last12 = Comas | first12 = David | last13 = Bertranpetit | first13 = Jaume | last14 = Tyler-Smith | first14 = Chris | last15 = Genographic | first15 = Consortium | title = Y-Chromosomal Diversity in Lebanon Is Structured by Recent Historical Events | journal = American Journal of Human Genetics | volume = 82 | issue = 4| pages = 873–882 | pmid = 18374297 | pmc = 2427286 | display-authors = 8 }} However, its presence in the Marsh Arabs(related to Sumer) of Iraq hints that Q-M25's West Asian history extends beyond a single localized recent founder.{{cite journal | doi = 10.1186/1471-2148-11-288 | title = In search of the genetic footprints of Sumerians: A survey of Y-chromosome and mtDNA variation in the Marsh Arabs of Iraq | year = 2011 | last1 = Al-Zahery | first1 = Nadia | last2 = Pala | first2 = Maria | last3 = Battaglia | first3 = Vincenza | last4 = Grugni | first4 = Viola | last5 = Hamod | first5 = Mohammed A | last6 = Kashani | first6 = Baharak | last7 = Olivieri | first7 = Anna | last8 = Torroni | first8 = Antonio | last9 = Santachiara-Benerecetti | first9 = Augusta S | last10 = Semino | first10 = Ornella | journal = BMC Evolutionary Biology | volume = 11 | issue = 1 | pages = 288 | pmid = 21970613 | pmc = 3215667 | bibcode = 2011BMCEE..11..288A | doi-access = free }}

class="wikitable"

! Population

Sampling LocationPaperNPercentageSNP Tested
Marsh ArabsAl-Zahery 20111/143~0.70%M25/ (cf)Q1b-M378=2.1%
IraqisAl-Zahery 20110/154~0.00%M25/ (cf)Q1b-M378=1.9%
IraniansIran (North)Regueiro 20063/33~9.09%M25
IraniansMazandaranDi Cristofaro 20131/13~7.69%M25
IraniansIran (South)Regueiro 20063/117~2.56%M25
IraniansEsfahanDi Cristofaro 20131/42~2.38%M25
AzerisIran (Azeri)Grugni 20121/63~1.60%M25
TurkmensGolestanGrugni 201229/68~42.6%M25
Lebanese (Non-Muslim)LebanonZalloua 20080/482~0.00%M25
Lebanese (Muslim)LebanonZalloua 20084/432~0.93%M25

=Europe=

Q-M25 is present across modern Turkey{{cite journal |vauthors=Cinnioğlu C, King R, Kivisild T, etal |title=Excavating Y-chromosome haplotype strata in Anatolia |journal=Hum. Genet. |volume=114 |issue=2 |pages=127–48 |date=January 2004 |pmid=14586639 |doi=10.1007/s00439-003-1031-4 |s2cid=10763736 }} and in Eastern Europe.

class="wikitable"

! Population

PaperNPercentageSNP Tested
East AnatoliaCinnioglu 20041/82~1.20%M25

Associated SNP's

Haplogroup Q-M25 is defined by the presence of the M25 Single Nucleotide Polymorphism (SNP) as well as the M143, L714, and L716 SNPs.

Phylogenetic Tree

This is Thomas Krahn at the Genomic Research Center's Draft tree [https://web.archive.org/web/20130526161518/http://ytree.ftdna.com/index.php?name=Draft&parent=8104789 Proposed Tree] for haplogroup Q-M25.

  • Q-M25 M25, M143, L714, L716
  • Q-L712 L712
  • Q-L713 L697.2, L713, L715, M365.3

See also

=Y-DNA Q-M242 Subclades=

= Y-DNA Backbone Tree =

{{Y-DNA}}

References