Harry Stone Mosher
{{Short description|American chemist}}
{{Infobox scientist
|name = Harry Stone Mosher
|image =
|image_size =
|caption = Harry Stone Mosher
|birth_date = {{Birth date|1915|08|31}}
|birth_place = Salem, Oregon, United States
|residence =
|death_date = {{death date and age|2001|03|02|1915|08|31}}
|death_place = Stanford, California, United States
|field =
|work_institution = Stanford University
|alma_mater = Willamette University, Pennsylvania State University
|doctoral_advisor = Frank C. Whitmore
|doctoral_students = Charles Frederick Wurster
|known_for = Mosher's acid
|prizes =
|footnotes =
}}Harry Stone Mosher (August 31, 1915 – March 2, 2001) was an American chemist and the discoverer of Mosher's acid.
Early life
Mosher attended Willamette University in Salem, Oregon, where he received a bachelor's degree in chemistry in 1937. He went on to Oregon State University, where he earned a master's degree in 1938. He then returned to Willamette to teach for one year. In 1939, he continued his graduate work at Pennsylvania State University under the mentorship of Frank C. Whitmore, a renowned organic chemist. In 1942, Mosher completed his PhD in organic chemistry. He remained at Pennsylvania State as an assistant professor, supervising research on synthetic anti-malarial drugs for the National Research Council and the production of DDT with the War Production Board. In 1944, Mosher married Carol Walker, a fellow chemistry graduate student at the university. Three years later, Mosher accepted an assistant professorship at Stanford University in the Department of Chemistry, and he and his wife moved to California for the position. That same year his wife Carol joined the staff of the Stanford Research Institute, later becoming senior organic chemist.{{Cite web|title = Memorial Resolution: Harry S. Mosher : 02/02|url = http://news.stanford.edu/news/2002/february27/moshermem-227.html|website = news.stanford.edu|accessdate = 2015-08-31}}
Research contributions
While at Stanford, Mosher taught organic chemistry and conducted research in natural products chemistry and stereochemistry. He and his graduate student Melanchton Brown identified a deadly toxin produced by the California newt living in Stanford's Lake Lagunita, calling it tarichatoxin. They soon discovered that it was the same toxin produced by the puffer fish, used in a rare type of sushi that if prepared incorrectly could paralyze and kill human diners. Mosher determined the structure of the toxin, which is known as tetrodotoxin.{{Cite news|title = Obituaries|url = https://www.latimes.com/archives/la-xpm-2001-mar-17-me-39095-story.html|newspaper = Los Angeles Times|date = 2001-03-17|access-date = 2015-08-31|issn = 0458-3035|language = en}} Mosher worked on many other natural products including both plant pigments and toxic substances.
Mosher also invented the "Mosher reagent" or Mosher's acid, which is used to measure the degree of left- or right-handedness in organic molecules.
Awards and honors
Mosher received an honorary doctoral degree from Willamette University. Harry Mosher served as chair of the California section of the American Chemical Society in 1955 and on the ACS National Council, both elected positions. In 1978, Mosher received the Abraham Ottenberg Service Award from the ACS.{{Cite web|url = http://www.scvacs.org/Local_Folder/Awards.html|title = The Abraham Ottenberg Service Award|date = |accessdate = 31 Aug 2015|website = The Santa Clara Valley Section of the American Chemical Society|publisher = American Chemical Society|last = |first = |archive-url = https://web.archive.org/web/20150318222228/http://www.scvacs.org/Local_Folder/Awards.html|archive-date = 18 March 2015|url-status = dead}} Two years later, the ACS established the Harry and Carol Mosher Award to advance the field of chemistry.{{cite web|title=Section Awards and Grants|url=http://scvacs.org/?page_id=44|website=American Chemical Society|accessdate=10 October 2017}}
Later life
References
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Category:20th-century American chemists