Hounsfield scale
{{Short description|Quantitative scale of radiodensity}}
The Hounsfield scale ({{IPAc-en|ˈ|h|aʊ|n|z|f|iː|l|d}} {{respell|HOWNZ|feeld}}), named after Sir Godfrey Hounsfield, is a quantitative scale for describing radiodensity. It is frequently used in CT scans, where its value is also termed CT number.
Definition
The Hounsfield unit (HU) scale is a linear transformation of the original linear attenuation coefficient measurement into one in which the radiodensity of distilled water at standard pressure and temperature (STP) is defined as 0 Hounsfield units (HU), while the radiodensity of air at STP is defined as −1000 HU. In a voxel with average linear attenuation coefficient , the corresponding HU value is therefore given by:{{Cite journal |last1=Levine |first1=Zachary H. |last2=Peskin |first2=Adele P. |last3=Holmgren |first3=Andrew D. |last4=Garboczi |first4=Edward J. |date=2018-12-20 |title=Preliminary X-ray CT investigation to link Hounsfield unit measurements with the International System of Units (SI) |journal=PLOS ONE |language=en |volume=13 |issue=12 |pages=e0208820 |doi=10.1371/journal.pone.0208820 |doi-access=free |issn=1932-6203 |pmc=6301669 |pmid=30571779}}{{Cite journal |last1=Hurrell |first1=Michael Anthony |last2=Butler |first2=Anthony Philip Howard |last3=Cook |first3=Nicholas James |last4=Butler |first4=Philip Howard |last5=Ronaldson |first5=J. Paul |last6=Zainon |first6=Rafidah |date=2012-05-01 |title=Spectral Hounsfield units: a new radiological concept |url=https://link.springer.com/article/10.1007/s00330-011-2348-3 |journal=European Radiology |language=en |volume=22 |issue=5 |pages=1008–1013 |doi=10.1007/s00330-011-2348-3 |pmid=22134894 |issn=1432-1084|url-access=subscription }}
where and are respectively the linear attenuation coefficients of water and air.
Thus, a change of one Hounsfield unit (HU) represents a change of 0.1% of the attenuation coefficient of water since the attenuation coefficient of air is nearly zero.{{cite book |title=Diagnostic radiology physics: a handbook for teachers and students |date=2014 |pages=1–682 |publisher=International Atomic Energy Agency |location=Vienna |isbn=978-92-0-131010-1 |url=https://www.iaea.org/publications/8841/diagnostic-radiology-physics}}{{rp|259}}
Calibration tests of HU with reference to water and other materials may be done to ensure standardised response. This is particularly important for CT scans used in radiotherapy treatment planning, where HU is converted to electron density.{{cite book |title=Radiation oncology physics: a handbook for teachers and students. |date=2005 |publisher=International Atomic Energy Agency |location=Vienna |isbn=92-0-107304-6 |page=230 |url=https://www.iaea.org/publications/7086/radiation-oncology-physics}} Variation in the measured values of reference materials with known composition, and variation between and within slices may be used as part of test procedures.{{rp|283}}{{cite book |title=AAPM Report No. 233: Performance Evaluation of Computed Tomography Systems - The Report of AAPM Task Group 233 |date=2019 |publisher=American Association of Physicists in Medicine |location=Alexandria, VA |isbn=978-1-936366-69-9 |url=https://www.aapm.org/pubs/reports/detail.asp?docid=186|doi=10.37206/186|last1=Samei |first1=Ehsan |last2=Bakalyar |first2=Donovan |last3=Boedeker |first3=Kirsten |last4=Brady |first4=Samuel |last5=Fan |first5=Jiahua |last6=Leng |first6=Shuai |last7=Myers |first7=Kyle |last8=Popescu |first8=Lucretiu |last9=Ramirez-Giraldo |first9=Juan Carlos |last10=Ranallo |first10=Frank |last11=Solomon |first11=Justin |last12=Vaishnav |first12=Jay |last13=Wang |first13=Jia |s2cid=214010953 }}
=Rationale=
The above standards were chosen originally to encode the radiodensity of organic tissues relative to water for 12-bit processing on clinical CT scanners.{{Cite journal |last=Jayamani |first=Jayapramila |last2=Osman |first2=Noor Diyana |last3=Tajuddin |first3=Abdul Aziz |last4=Salehi |first4=Zaker |last5=Ali |first5=Mohd Hanafi |last6=Abdul Aziz |first6=Mohd Zahri |date=2019-02-19 |title=Determination of computed tomography number of high-density materials in 12-bit, 12-bit extended and 16-bit depth for dosimetric calculation in treatment planning system |url=https://doi.org/10.1017/s1460396919000013 |journal=Journal of Radiotherapy in Practice |volume=18 |issue=03 |pages=285–294 |doi=10.1017/s1460396919000013 |issn=1460-3969|url-access=subscription }} A 12-bit encoding corresponds to 4096 () values, where the range (–1024 to 3071) encompasses HU values for air, soft tissue and bone.
Values for different body tissues and material
File:CT Scan Thorax Lung -700 HU Window Level.jpg
File:CT Scan Thorax Air -1000 HU Window Level.jpg
File:CT Scan Thorax Water 0 HU Window Level.jpg
File:CT Scan Thorax Liver 60 HU Window Level.jpg
HU-based differentiation of material applies to medical-grade dual-energy CT scans but not to cone beam computed tomography (CBCT) scans, as CBCT scans provide unreliable HU readings.{{cite journal |last1=De Vos| first1= W. |last2=Casselman|first2=J.|last3=Swennen|first3=G.R.J.|date=June 2009|title=Cone-beam computerized tomography (CBCT) imaging of the oral and maxillofacial region: A systematic review of the literature|journal=International Journal of Oral and Maxillofacial Surgery|volume=38|issue=6|pages=609–625| doi= 10.1016/j.ijom.2009.02.028|pmid=19464146}}
Values reported here are approximations. Different dynamics are reported from one study to another.{{cn|date=July 2024}}
Exact HU dynamics can vary from one CT acquisition to another due to CT acquisition and reconstruction parameters (kV, filters, reconstruction algorithms, etc.). The use of contrast agents modifies HU as well in some body parts (mainly blood).
A practical application of this is in evaluation of tumors, where, for example, an adrenal tumor with a radiodensity of less than 10 HU is rather fatty in composition and almost certainly a benign adrenal adenoma.{{cite web| url= http://emedicine.medscape.com/article/376240 |title= Adrenal Adenoma Imaging| first= Perry J.| last= Horwich| editor= Eugene C Lin| date= December 20, 2018| website= Medscape | access-date= July 28, 2023}}
See also
References
{{reflist}}
- {{cite book
|last=Feeman
|first=Timothy G.
|title=The Mathematics of Medical Imaging: A Beginner's Guide
|series=Springer Undergraduate Texts in Mathematics and Technology
|publisher=Springer
|year=2010
|isbn=978-0387927114
}}
External links
- {{cite web|url=http://www.medcyclopaedia.com/library/topics/volume_i/h/hounsfield_unit.aspx|archive-url=https://archive.today/20120404030558/http://www.medcyclopaedia.com/library/topics/volume_i/h/hounsfield_unit.aspx|url-status=dead|archive-date=2012-04-04|title=Hounsfield unit|publisher=GE|website=Medcyclopaedia}}
- [http://www.fpnotebook.com/Rad/CT/HnsfldUnt.htm Hounsfield Unit] - fpnotebook.com
- {{cite web|url=http://www.intl.elsevierhealth.com/e-books/pdf/940.pdf|title=Introduction to CT physics|publisher=elsevierhealth.com|archive-url=https://web.archive.org/web/20070926231241/http://www.intl.elsevierhealth.com/e-books/pdf/940.pdf|archive-date=2007-09-26}}
- [https://www.researchgate.net/publication/24234798_Imaging_of_deep_brain_stimulation_leads_using_extended_Hounsfield_unit_CT Imaging of deep brain stimulation leads using extended Hounsfield unit CT. Stereotact Funct Neurosurg. 2009;87(3):155-60. doi: 10.1159/000209296]
{{Medical imaging}}