IGK@

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Immunoglobulin kappa locus, also known as IGK@, is a region on the p arm of human chromosome 2, region 11.2 (2p11.2), that contains genes for the kappa (κ) light chains of antibodies (or immunoglobulins).{{cite journal |vauthors=Criscitiello MF, Flajnik MF |title=Four primordial immunoglobulin light chain isotypes, including lambda and kappa, identified in the most primitive living jawed vertebrates |journal=Eur. J. Immunol. |volume=37 |issue=10 |pages=2683–94 |year=2007 |pmid=17899545 |doi=10.1002/eji.200737263|pmc=7094790 }}

In humans the κ chain is coded for by V (variable), J (joining) and C (constant) genes in this region.Male, D., Brostoff, J., Roth, D.B., & Roitt, I. 2006. Immunology. 7th ed., Canada: Elsevier Limited These genes undergo V(D)J recombination to generate a diverse repertoire of immunoglobulins.