JAMA Network Open

{{Infobox journal

| title = JAMA Network Open

| cover = File:JAMA_Network_Open_Journal_Cover_Image.png

| caption =

| former_name =

| abbreviation = JAMA Netw. Open

| discipline = Medicine

| editor = Eli Perencevich

| publisher = American Medical Association

| country =

| history = 2018-present

| frequency = Monthly

| openaccess = Yes

| license = CC BY, CC BY-NC-ND

| impact = 13.353

| impact-year = 2021

| eISSN = 2574-3805

| CODEN =

| JSTOR =

| LCCN = 2017201880

| OCLC = 1001466479

| website = https://jamanetwork.com/journals/jamanetworkopen

| link1 = https://jamanetwork.com/journals/jamanetworkopen/currentissue

| link1-name = Online access

| link2 =

| link2-name =

}}

JAMA Network Open is a monthly open access medical journal published by the American Medical Association covering all aspects of the biomedical sciences. It was established in 2018 and the founding editor-in-chief was Fred Rivara (University of Washington); since 2024, the Eli Perencevich (University of Iowa) has been editor-in-chief.{{cite web|title=For Authors|publisher=JAMA|url=https://jamanetwork.com/journals/jamanetworkopen/pages/for-authors|accessdate=27 September 2024}} The journal is funded by article processing charges and most articles are available under a Creative Commons license. Article titles and abstracts are translated into Spanish and Chinese. According to Journal Citation Reports, the journal has a 2021 impact factor of 13.353, ranking it 15th out of 172 journals in the category "Medicine, General & Internal". Additionally, it ranks 5th among purely open access journals in that subject category. {{cite book |year=2022 |chapter=Journals Ranked by Impact |title=2022 Release of Journal Citation Reports™ |publisher=Clarivate Analytics |edition=Science |series=Web of Science |title-link=Journal Citation Reports}}