Klaas de Groot
{{Short description|Dutch bioengineer (1940–2024)}}
{{for|the Dutch Olympic wrestler|Klaas de Groot (wrestler)}}
{{Use dmy dates|date=January 2024}}
{{Infobox scientist
| name = Klaas de Groot
| image = DeGroot.jpg
| caption =
| birth_date = {{birth date|1940|11|3|df=y}}
| birth_place = Bergen, Limburg, German-occupied Netherlands
| death_date = {{death date and age|2024|01|15|1940|11|3|df=y}}
| death_place = Heemstede, Netherlands
| nationality = 20px The Netherlands
| field = Biomedical Engineering, Biomaterials, Tissue Engineering
| work_institution = University of Twente
| prizes = Chinese Friendship award;
The Clemson award (USA);
The George Winter award (EU);
The Somiya Award (2003);
The John Charnley Award (by the USA Hip Society); The Gold Medal by Acta Biomaterialia
| footnotes =
}}
Klaas de Groot (3 November 1940 – 15 January 2024) was a Dutch bioengineer. He worked as professor at Leiden University and the University of Twente.
Early life
De Groot was born on 3 November 1940 in Bergen, Limburg.[http://www.journals.elsevier.com/acta-biomaterialia/news/acta-biomaterialia-gold-medal-2016-awarded-to-klaas-de-groot/ Acta Biomaterialia Gold Medal 2016 awarded to Klaas de Groot]{{cite web|url=https://hoogleraren.universiteitleiden.nl/id/985 |archive-url=https://web.archive.org/web/20240121120752/https://hoogleraren.universiteitleiden.nl/id/985 |title=Klaas de Groot |language=nl |publisher=Leiden University |date= |archive-date=21 January 2024}} He obtained his PhD at the University of Groningen in 1968 with a thesis titled:"Photoionization of aromatic hydrocarbons in liquid solutions".
Career
In 1988 de Groot became professor of biomaterials at Leiden University. He later became professor at the Tissue Engineering Group at the University of Twente.[https://archive.today/20110809223216/http://tr.tnw.utwente.nl/former_students/emeritus_prof._dr._klaas_de_gr/klaas_final1.doc/ Klaas de Groot faculty profile at University of Twente]
De Groot also worked as a visiting scientist at the UCLA bone research laboratory. His work focused on the research and development of bioceramics that resemble the composition of bone. He developed two types of bioceramic, namely bulk ceramics (dense, porous, large and small) for mechanically unloaded bone fillers, and coatings for improving the bone bonding of strong, but less biocompatible, metallic orthopedic and dental implants. His group also studied the incorporation of drugs and growth factors such as Bone Morphogenetic Proteins (BMP){{cite journal|pmid=9916166 | volume=4 | issue=4 | title=Carriers that concentrate native bone morphogenetic protein in vivo | year=1998 | journal=Tissue Eng. | pages=337–41 | doi=10.1089/ten.1998.4.337 | last1 = De Groot | first1 = J}} into such ceramics and coatings,{{cite journal
|author2=Y Liu, K de Groot, E B Hunziker
| title = BMP-2 liberated from biomimetic implant coatings induces and sustains direct ossification in an ectopic rat model
| journal = Bone
| volume = 36
| issue = 5
| pages = 745–57
| date =May 2005
| url = https://www.researchgate.net/publication/7922738
| issn = 8756-3282
| doi = 10.1016/j.bone.2005.02.005
| pmid =15814303
| last1 =Liu
| first1 =Y }}
as well as the use of calciumphosphate particles for plastic surgery, i.e. filling and augmenting soft and hard tissues for cosmetic reasons{{cite journal
|author=P Habibovic, C M van der Valk, C A van Blitterswijk, K De Groot, G Meijer
| title = Influence of octacalcium phosphate coating on osteoinductive properties of biomaterials
| journal = Journal of Materials Science: Materials in Medicine
| year = 2004
| volume = 2004/04
| issue = 15(4)
| pages = 373–80
| doi = 10.1023/b:jmsm.0000021104.42685.9f
| url = https://www.researchgate.net/publication/8378960
| issn=0957-4530
| pmid =15332602
| s2cid = 24892542
}}
).
CAM Implants
De Groot's research products are being marketed by CAM Implants (now Cam Bioceramics), IsoTis and Stryker (USA).
Prior to his present appointment he worked at Vrije Universiteit (VU), Amsterdam (until 1988) and Leiden University (until 2001), at both places as head of the department of biomaterials.
De Groot was a co-founder of CAM Implants BV (now Cam Bioceramics), and IsoTis. He published more than 350 articles and he was the co-inventor of about 10 patents.
Death
De Groot died in Heemstede on 15 January 2024, at the age of 83.{{cite news|url=https://images.nrc.nl/7dI8dz1iBtbsUlSv8LCTOeuh93c=/x/filters:no_upscale():format(jpeg):fill(f8f8f8,true)/s3/nrchub/clippings/NH/20240120/422-advertisement-267854_1320946_groot01-9d17ee.png |archive-url=https://web.archive.org/web/20240121115801/https://images.nrc.nl/7dI8dz1iBtbsUlSv8LCTOeuh93c=/x/filters:no_upscale%28%29:format%28jpeg%29:fill%28f8f8f8,true%29/s3/nrchub/clippings/NH/20240120/422-advertisement-267854_1320946_groot01-9d17ee.png |title=Klaas de Groot |language=nl |newspaper=NRC Handelsblad |date=20 January 2024 |archive-date=21 January 2024}}
References
{{Reflist}}
{{Authority control}}
{{DEFAULTSORT:Groot, Klaas De}}
Category:Academic staff of Leiden University
Category:Academic staff of Vrije Universiteit Amsterdam
Category:Academic staff of the University of Twente
Category:People from Bergen, Limburg
Category:University of Groningen alumni
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