LHFP
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Lipoma HMGIC fusion partner is a protein that in humans is encoded by the LHFP gene.{{cite journal |vauthors=Petit MM, Schoenmakers EF, Huysmans C, Geurts JM, Mandahl N, Van de Ven WJ | title = LHFP, a novel translocation partner gene of HMGIC in a lipoma, is a member of a new family of LHFP-like genes | journal = Genomics | volume = 57 | issue = 3 | pages = 438–41 |date=Aug 1999 | pmid = 10329012 | doi = 10.1006/geno.1999.5778 }}{{cite web | title = Entrez Gene: LHFP lipoma HMGIC fusion partner| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10186}}
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. This gene is fused to a high-mobility group gene in a translocation-associated lipoma. Mutations in another LHFP-like gene (LHFPL1, LHFPL2) result in deafness in humans and mice. Alternatively spliced transcript variants have been found; however, their full-length nature is not known.
References
{{reflist}}
Further reading
{{refbegin | 2}}
- {{cite journal |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
- {{cite journal |vauthors=Longo-Guess CM, Gagnon LH, Cook SA, etal |title=A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 22 |pages= 7894–9 |year= 2005 |pmid= 15905332 |doi= 10.1073/pnas.0500760102 | pmc=1142366 |bibcode=2005PNAS..102.7894L |doi-access=free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Dunham A, Matthews LH, Burton J, etal |title=The DNA sequence and analysis of human chromosome 13 |journal=Nature |volume=428 |issue= 6982 |pages= 522–8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379 | pmc=2665288 |bibcode=2004Natur.428..522D }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
- {{cite journal |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
{{refend}}
External links
- {{UCSC genome browser|LHFP}}
- {{UCSC gene details|LHFP}}
{{gene-13-stub}}