Michalis Karlis

{{Short description|Greek basketball player}}

{{Infobox basketball biography

| name = Michalis Karlis

| image =

| image_size =

| caption = Karlis with AEK Athens B.C. in 2022

| position = Point guard

| height_ft = 6

| height_in = 1

| weight_lbs = 186

| league = Greek B Basket League

| team = N.O. Saronidas

| number =

| nationality = Greek

| birth_date = {{birth date and age|2003|1|8|df=y}}

| birth_place = Nea Alikarnassos, Heraklion{{Cite web |date=2018-07-04 |title=Από τον Ηρόδοτο στην ΑΕΚ ο Μιχάλης Καρλής |url=https://www.neakriti.gr/article/sport/1514198/apo-ton-irodoto-stin-aek-o-mihalis-karlis/ |access-date=2022-08-22 |website=Νέα Κρήτη |language=el}}

| high_school =

| college =

| draft_year =

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| career_start = 2021

| career_end =

| years1 = 2021–2022

| team1 = AEK Athens

| years2 = 2022–2023

| team2 = Raiffeisen Dornbirn Lions

| years3 = 2023-2024

| team3 = Anagennisi Arkalochoriou

| years4 = 2024-2025

| team4 = Asteras Temenis

| years5 = 2025-2026

| team5 = N.O. Saronidas

| highlights =

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}}

Michalis Karlis ({{langx|el|Μιχάλης Καρλής}}; born 8 January 2003) is a Greek professional basketball player for the Asteras Temenis of the National League 2 . He is a {{convert|1.86|m|ftin|abbr=on}} tall point guard.