Midol

{{Short description|Brand of analgesics for menstrual cramping}}

{{About|the pain relief drug|the similarly-named South Korean television series|MyDOL}}

File:Midol Modern Packaging 2023.jpgFile:Peggy's bright with MIDOL, 1960.jpg

Midol is a brand of over-the-counter analgesic drugs marketed for menstrual cramping and other effects related to premenstrual syndrome and menstruation. Various subbrands are formulated using different active ingredients. Midol is distributed by Bayer.

Midol was originally sold in 1911 as a headache and toothache remedy that was considered safer because it did not use the narcotics typically used at the time.{{Cite web |url=http://www.mum.org/midoslog.jpg |title=Midol ad for Headache--Neuralgia, Toothache |access-date=2010-07-03 |archive-date=2010-06-20 |archive-url=https://web.archive.org/web/20100620002744/http://mum.org/midoslog.jpg |url-status=live }} It was then promoted as a cure for hiccups claiming it controlled spasms, and finally as a remedy for menstrual cramps and bloating.{{Cite web |url=http://www.mum.org/midol11x.jpg |title=Midol for Hiccoughs |access-date=2010-07-03 |archive-date=2010-06-15 |archive-url=https://web.archive.org/web/20100615092221/http://mum.org/midol11x.jpg |url-status=live }}{{Cite web |url=http://www.mum.org/news.htm |title=News at Museum of Menstruation and women's health |access-date=2010-07-03 |archive-date=2010-06-15 |archive-url=https://web.archive.org/web/20100615092129/http://mum.org/news.htm |url-status=live }}{{Cite web |url=http://contexts.org/socimages/files/2008/07/gender-bettys-gay-with-midol.jpg |title=Midol ad for Menstrual problems |access-date=2010-07-03 |archive-date=2012-07-08 |archive-url=https://archive.today/20120708022103/http://contexts.org/socimages/files/2008/07/gender-bettys-gay-with-midol.jpg |url-status=live }}{{Cite web |url=http://contexts.org/socimages/files/2008/07/gender-reverse-the-curse.jpg |title=Midol "Reverse the Curse" ad |access-date=2010-07-03 |archive-date=2012-07-07 |archive-url=https://archive.today/20120707080842/http://contexts.org/socimages/files/2008/07/gender-reverse-the-curse.jpg |url-status=live }} A formulation sold in the 1980s was made with the sympathomimetic cinnamedrine.KW Fellows, AJ Giannini. Cinnamedrine: Potential for Abuse. Journal of Toxicology:Clinical Toxicology. 20:93–99.1983. It had been reported to have abuse potential as an appetite suppressant and sympathomimetic agent. Midol, like other NSAID class of drugs, may have side effects for some, such as an increased risk of bleeding, kidney damage or negative effects on cardiovascular system.{{Cite web|url=http://thechart.blogs.cnn.com/2010/06/10/pain-relievers-connected-to-heart-deaths/|title=Pain relievers connected to heart deaths|access-date=2018-12-05|archive-date=2018-12-05|archive-url=https://web.archive.org/web/20181205103602/http://thechart.blogs.cnn.com/2010/06/10/pain-relievers-connected-to-heart-deaths/|url-status=dead}}

The "Midol Complete" formulation consists of:

• Acetaminophen 500 mg (pain reliever)
• Caffeine 60 mg (stimulant)
• Pyrilamine maleate 15 mg (antihistamine)

The "Extended Relief" formulation consists of:

• Naproxen sodium 220 mg (NSAID, pain reliever/fever reducer)

The "Teen" formulation consists of:

• Acetaminophen 500 mg (pain reliever)
• Pamabrom 25 mg (diuretic)

The "Liquid Gels" (Labeled MAXIDOL){{Cite web |title=MAXIDOL® LIQUID GELS |url=https://www.midol.ca/en/midol-products/maxidol |access-date=2024-11-08 |website=MAXIDOL® LIQUID GELS |language=en-ca}} formulation consists of:

• Ibuprofen 200 mg (NSAID, pain reliever)

The "PM" formulation consists of:

• Acetaminophen 500 mg (pain reliever)
• Diphenhydramine citrate 38 mg (sedative antihistamine)