NeXtProt

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{{coi|date=July 2018}}

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{{infobox biodatabase

|title = neXtProt

|logo = right

|description = neXtProt: exploring the universe of human proteins

|scope = Protein annotation

|organism = Human

|center = Swiss Institute of Bioinformatics

|laboratory = CALIPHO

|author =

|citation = Gaudet, et al. (2016){{cite journal|last1=Gaudet|first1=P|last2=Michel|first2=PA|last3=Zahn-Zabal|first3=M|last4=Britan|first4=A|last5=Cusin|first5=I|last6=Domagalski|first6=M|last7=Duek|first7=PD|last8=Gateau|first8=A|last9=Gleizes|first9=A|last10=Hinard|first10=V|last11=de Laval|first11=VR|last12=Lin|first12=J|last13=Nikitin|first13=F|last14=Schaeffer|first14=M|last15=Teixeira|first15=D|last16=Lane|first16=L|last17=Bairoch|first17=A|title=The neXtProt knowledgebase on human proteins: 2017 update.|journal=Nucleic Acids Research|date=29 November 2016|pmid=27899619|doi=10.1093/nar/gkw1062|volume=45|issue=D1|pmc=5210547|pages=D177–D182}}

|pmid =

|released =

|standard =

|format =

|url = {{URL|www.nextprot.org}}

|download =

|webservice =

|sql =

|sparql =

|webapp = Search, BLAST, SNORQL

|standalone =

|news =

|license = Creative Commons Attribution 4.0

|versioning = Yes

|frequency = Data: 3 times per year

|curation = Yes - manual and automatic

|bookmark = Yes - individual protein entries views and searches

|version =

}}

neXtProt is an on-line knowledge platform on human proteins.

It strives to be a comprehensive resource that provides a variety of

types of information on human proteins, such as their function,

subcellular location, expression, interactions and role in diseases.

The major part of the information in neXtProt

{{cite journal |author=Lane Lydie|title=neXtProt: a knowledge platform for human proteins |journal=Nucleic Acids Research |volume=40 |pages=D76–D83 |year=2012 |pmid=22139911 |doi=10.1093/nar/gkr1179 |issue=Database issue |pmc=3245017}}

is obtained from the UniProt Swiss-Prot database but it is complemented by data originating from high-throughput studies with an emphasis on proteomics. neXtProt offers also an advanced search capacity based on the SPARQL technology as well as an API that allows to programmatically extract the data stored in the resource. It is developed by the CALIPHO group[http://www.isb-sib.ch/bairoch-amos-lane-lydie/bairoch-amos-lane-lydie-sub CALIPHO group], on the web site of the SIB directed by Amos Bairoch and Lydie Lane of the Swiss Institute of Bioinformatics (SIB).

References

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