Login
Login

PIK3R5

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{cs1 config|name-list-style=vanc|display-authors=3}}

{{Infobox_gene}}

Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene.{{cite journal |vauthors=Brock C, Schaefer M, Reusch HP, Czupalla C, Michalke M, Spicher K, Schultz G, Nurnberg B | title = Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma | journal = J Cell Biol | volume = 160 | issue = 1 | pages = 89–99 |date=Jan 2003 | pmid = 12507995 | pmc = 2172741 | doi = 10.1083/jcb.200210115 }}{{cite web | title = Entrez Gene: PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5, p101| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23533| accessdate = }}

Interactions

PIK3R5 has been shown to interact with PIK3CG.

References

{{reflist}}

Further reading

{{refbegin | 2}}

  • {{cite journal |vauthors=Johnson C, Marriott SJ, Levy LS |title=Overexpression of p101 activates PI3Kgamma signaling in T cells and contributes to cell survival |journal=Oncogene |volume=26 |issue= 49 |pages= 7049–57 |year= 2007 |pmid= 17486067 |doi= 10.1038/sj.onc.1210504 |doi-access= free }}
  • {{cite journal | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 | author2=Venkatesan K | author3=Hao T | last4=Hirozane-Kishikawa | first4=Tomoko | last5=Dricot | first5=Amélie | last6=Li | first6=Ning | last7=Berriz | first7=Gabriel F. | last8=Gibbons | first8=Francis D. | last9=Dreze | first9=Matija |bibcode=2005Natur.437.1173R |s2cid=4427026 }}
  • {{cite journal | author=Suire S |title=p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma |journal=Curr. Biol. |volume=15 |issue= 6 |pages= 566–70 |year= 2005 |pmid= 15797027 |doi= 10.1016/j.cub.2005.02.020 | author2=Coadwell J | author3=Ferguson GJ | last4=Davidson | first4=Keith | last5=Hawkins | first5=Phillip | last6=Stephens | first6=Len |s2cid=12255918 |doi-access=free|bibcode=2005CBio...15..566S }}
  • {{cite journal |vauthors=Voigt P, Brock C, Nürnberg B, Schaefer M |title=Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma |journal=J. Biol. Chem. |volume=280 |issue= 6 |pages= 5121–7 |year= 2005 |pmid= 15611065 |doi= 10.1074/jbc.M413104200 |doi-access= free }}
  • {{cite journal | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 | author2=Wagner L | author3=Feingold EA | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author2=Feingold EA | author3=Grouse LH | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Metjian A, Roll RL, Ma AD, Abrams CS |title=Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus |journal=J. Biol. Chem. |volume=274 |issue= 39 |pages= 27943–7 |year= 1999 |pmid= 10488142 |doi=10.1074/jbc.274.39.27943 |doi-access=free }}
  • {{cite journal |vauthors=Krugmann S, Hawkins PT, Pryer N, Braselmann S |title=Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits |journal=J. Biol. Chem. |volume=274 |issue= 24 |pages= 17152–8 |year= 1999 |pmid= 10358071 |doi=10.1074/jbc.274.24.17152 |doi-access=free }}

{{refend}}

{{gene-17-stub}}