PJA2
{{Short description|Protein-coding gene in the species Homo sapiens}}
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E3 ubiquitin-protein ligase Praja2 is an enzyme that in humans is encoded by the PJA2 gene.{{cite web | title = Entrez Gene: PJA2 praja 2, RING-H2 motif containing| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9867| access-date = }}
Interactions
PJA2 has been shown to interact with UBE2D2.{{cite journal | vauthors = Yu P, Chen Y, Tagle DA, Cai T | title = PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain | journal = Genomics | volume = 79 | issue = 6 | pages = 869–74 | date = June 2002 | pmid = 12036302 | doi = 10.1006/geno.2002.6770 | url = https://zenodo.org/record/1229812 }}
References
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Further reading
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- {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = November 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 | s2cid = 7827573 | doi-access = free }}
- {{cite journal | vauthors = Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S | title = Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions | journal = Genome Research | volume = 14 | issue = 9 | pages = 1711–8 | date = September 2004 | pmid = 15342556 | pmc = 515316 | doi = 10.1101/gr.2435604 }}
- {{cite journal | vauthors = Yu P, Chen Y, Tagle DA, Cai T | title = PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain | journal = Genomics | volume = 79 | issue = 6 | pages = 869–74 | date = June 2002 | pmid = 12036302 | doi = 10.1006/geno.2002.6770 | url = https://zenodo.org/record/1229812 }}
- {{cite journal | vauthors = Sasaki A, Masuda Y, Iwai K, Ikeda K, Watanabe K | title = A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 25 | pages = 22541–6 | date = June 2002 | pmid = 11959851 | doi = 10.1074/jbc.M109728200 | doi-access = free }}
- {{cite journal | vauthors = Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Research | volume = 4 | issue = 5 | pages = 307–13 | date = October 1997 | pmid = 9455477 | doi = 10.1093/dnares/4.5.307 | doi-access = free }}
- {{cite journal | vauthors = Mishra L, Tully RE, Monga SP, Yu P, Cai T, Makalowski W, Mezey E, Pavan WJ, Mishra B | title = Praja1, a novel gene encoding a RING-H2 motif in mouse development | journal = Oncogene | volume = 15 | issue = 19 | pages = 2361–8 | date = November 1997 | pmid = 9393880 | doi = 10.1038/sj.onc.1201405 | doi-access = free }}
- {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Research | volume = 6 | issue = 9 | pages = 791–806 | date = September 1996 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 | doi-access = free }}
- {{cite journal | vauthors = Nakayama M, Miyake T, Gahara Y, Ohara O, Kitamura T | title = A novel RING-H2 motif protein downregulated by axotomy: its characteristic localization at the postsynaptic density of axosomatic synapse | journal = The Journal of Neuroscience | volume = 15 | issue = 7 Pt 2 | pages = 5238–48 | date = July 1995 | pmid = 7623148 | doi = 10.1523/JNEUROSCI.15-07-05238.1995| pmc = 6577874 }}
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