PPP6C
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Serine/threonine-protein phosphatase 6 catalytic subunit is an enzyme that in humans is encoded by the PPP6C gene.{{cite journal | vauthors = Bastians H, Krebber H, Vetrie D, Hoheisel J, Lichter P, Ponstingl H, Joos S | title = Localization of the novel serine/threonine protein phosphatase 6 gene (PPP6C) to human chromosome Xq22.3 | journal = Genomics | volume = 41 | issue = 2 | pages = 296–7 | date = April 1997 | pmid = 9143513 | doi = 10.1006/geno.1997.4640 }}{{cite web | title = Entrez Gene: PPP6C protein phosphatase 6, catalytic subunit| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5537}}
Interactions
PPP6C has been shown to interact with IGBP1.{{cite journal | vauthors = Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R | display-authors = 6 | title = A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity | journal = Molecular & Cellular Proteomics | volume = 4 | issue = 11 | pages = 1725–40 | date = November 2005 | pmid = 16085932 | doi = 10.1074/mcp.M500231-MCP200 | doi-access = free }}{{cite journal | vauthors = Chen J, Peterson RT, Schreiber SL | title = Alpha 4 associates with protein phosphatases 2A, 4, and 6 | journal = Biochemical and Biophysical Research Communications | volume = 247 | issue = 3 | pages = 827–32 | date = June 1998 | pmid = 9647778 | doi = 10.1006/bbrc.1998.8792 }}
References
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Further reading
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- {{cite journal | vauthors = Bastians H, Ponstingl H | title = The novel human protein serine/threonine phosphatase 6 is a functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation | journal = Journal of Cell Science | volume = 109 ( Pt 12) | issue = Pt 12 | pages = 2865–74 | date = December 1996 | doi = 10.1242/jcs.109.12.2865 | pmid = 9013334 }}
- {{cite journal | vauthors = Chen J, Peterson RT, Schreiber SL | title = Alpha 4 associates with protein phosphatases 2A, 4, and 6 | journal = Biochemical and Biophysical Research Communications | volume = 247 | issue = 3 | pages = 827–32 | date = June 1998 | pmid = 9647778 | doi = 10.1006/bbrc.1998.8792 }}
- {{cite journal | vauthors = Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G | display-authors = 6 | title = A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway | journal = Nature Cell Biology | volume = 6 | issue = 2 | pages = 97–105 | date = February 2004 | pmid = 14743216 | doi = 10.1038/ncb1086 | s2cid = 11683986 }}
- {{cite journal | vauthors = Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL | display-authors = 6 | title = High-throughput mapping of a dynamic signaling network in mammalian cells | journal = Science | volume = 307 | issue = 5715 | pages = 1621–5 | date = March 2005 | pmid = 15761153 | doi = 10.1126/science.1105776 | bibcode = 2005Sci...307.1621B | s2cid = 39457788 }}
- {{cite journal | vauthors = Nasu-Nishimura Y, Hayashi T, Ohishi T, Okabe T, Ohwada S, Hasegawa Y, Senda T, Toyoshima C, Nakamura T, Akiyama T | display-authors = 6 | title = Role of the Rho GTPase-activating protein RICS in neurite outgrowth | journal = Genes to Cells | volume = 11 | issue = 6 | pages = 607–14 | date = June 2006 | pmid = 16716191 | doi = 10.1111/j.1365-2443.2006.00966.x | s2cid = 7935936 | doi-access = }}
- {{cite journal | vauthors = Stefansson B, Brautigan DL | title = Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon | journal = The Journal of Biological Chemistry | volume = 281 | issue = 32 | pages = 22624–34 | date = August 2006 | pmid = 16769727 | doi = 10.1074/jbc.M601772200 | doi-access = free }}
- {{cite journal | vauthors = Stefansson B, Brautigan DL | title = Protein phosphatase PP6 N terminal domain restricts G1 to S phase progression in human cancer cells | journal = Cell Cycle | volume = 6 | issue = 11 | pages = 1386–92 | date = June 2007 | pmid = 17568194 | doi = 10.4161/cc.6.11.4276 | doi-access = free }}
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