Peter Openshaw (immunologist)

Openshaw was born in 1954 in Glastonbury, Somerset. He attended Millfield Junior School, then the Quaker boarding schools Sidcot School and Bootham School, followed by Guy's Hospital Medical School (University of London). He earned an intercalated BSc in Physiology (Hons., 1976), qualified in medicine (MB BS, 1979), and worked at the Royal Brompton Hospital and as medical registrar at Royal Postgraduate Medical School (Hammersmith Hospital).

;Immunological work

Originally trained in lung mechanics, his PhD at the National Institute for Medical Research at Mill Hill, London was in T cell immunology.{{Cite web |title=Future Virology Editorial Board |url=https://www.futuremedicine.com/journals/fvl/editors?publicationCode=fvl |access-date=2024-03-10 |website=Future Virology |language=en}} He has worked on protective and harmful immunological reactions to viruses, inflammatory lung disease and vaccine development since 1985, writing over 300 scientific articles (h-index= 101).{{Cite web |title=Peter Openshaw |url=https://scholar.google.com/citations?user=SzgPZAUAAAAJ&hl=en |access-date=2024-03-10 |website=scholar.google.com}} He was President of the British Society for Immunology between 2013 and 2018, the first clinician to hold the role. Openshaw was a member of the Academy of Medical Sciences and British Society for Immunology expert taskforce on COVID-19.{{Cite web |title=Peter Openshaw |url=https://www.imperial.ac.uk/people/p.openshaw |access-date=2024-03-10 |website=www.imperial.ac.uk}}

;Respiratory virus research

He was awarded the Chanock prize (2012, Santa Fe USA) in recognition of his lifetime achievement in work on respiratory syncytial virus (RSV) research. He has been involved in influenza policy since 2002 as a member of UK advisory boards and was Vice President of European Scientific Working Group on Influenza (ESWI) from 2009-2014. In 2009 he set up the MOSAIC consortium, a collaboration of 45 co-investigators studying the host response to influenza in patients admitted to 11 hospitals in London and Liverpool (Wellcome Trust/MRC support) and directs studies of viral challenge of human volunteers.

He was Theme Lead for the Respiratory Theme and later the Infection Theme of the NIHR Imperial Biomedical Research Centre. Currently he works as Head of the Respiratory Infections Section at the National Heart and Lung Institute, a department of Imperial College London.

;Academic leadership

Openshaw established the academic department of Respiratory Medicine on the St Mary’s Campus of Imperial College and created the Centre for Respiratory Infection (Wellcome Trust funded). He has sat on numerous governmental, grant awarding and international committees.

He was elected an Imperial College Consul for the Faculty of Medicine in 2016, becoming Senior Consul in 2019{{Cite web |date=2019-05-30 |title=Professor Peter Openshaw elected as Senior Consul at Imperial |url=https://www.imperial.ac.uk/news/191369/professor-peter-openshaw-elected-senior-consul/ |access-date=2024-03-11 |website=Imperial News |language=en}} and then Proconsul.{{Cite web |title=Knighthoods for Chief Medical Officers in COVID Dominated New Year Honours |url=https://www.medscape.co.uk/viewarticle/knighthoods-chief-medical-officers-covid-dominated-new-year-2022a100000a |access-date=2024-03-11 |website=Medscape UK |language=en}} He co-chaired Imperial's Working Together Task Group in 2021.{{Cite web |title=Working Together Task Group |url=https://www.imperial.ac.uk/about/leadership-and-strategy/provost/working-together-task-group/ |access-date=2024-03-11 |website=Imperial College London |language=en-GB}}

;Advisory

Openshaw is a member of the New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) in the UK.{{Cite web|url=https://www.gov.uk/government/groups/new-and-emerging-respiratory-virus-threats-advisory-group|title=New and Emerging Respiratory Virus Threats Advisory Group|website=GOV.UK|language=en|access-date=2020-03-20}}

Openshaw is a Fellow of the Royal College of Physicians (1994), a Fellow of the Academy of Medical Sciences (1999) and a Fellow of the Society of Biology (2014).{{Cite web |title=Honours and Memberships - Peter Openshaw - Professor of Experimental Medicine |url=https://www.imperial.ac.uk/people/p.openshaw/honours-and-memberships.html |access-date=2024-03-11 |website=www.imperial.ac.uk}} He was selected as Senior Investigator by National Institute for Health Research (NIHR) in 2013 and 2020.{{Cite web |last=Openshaw |first=Peter |date=2017-10-04 |title=Vaccines are vital: there's never been a more exciting time to be a vaccinologist! |url=https://blogs.imperial.ac.uk/imperial-medicine/2017/10/04/vaccines-are-vital/ |access-date=2024-03-11 |website=Imperial Medicine Blog |language=en-GB}}{{Cite web |title=NIHR Senior Investigator awards for Imperial |url=https://imperialbrc.nihr.ac.uk/2020/02/19/nihr-si/ |access-date=2024-03-11 |website=NIHR Imperial Biomedical Research Centre |language=en-GB}}

Openshaw was appointed Commander of the Order of the British Empire (CBE) in the 2022 New Year Honours for services to medicine and immunology.{{London Gazette|issue=63571|supp=y|page=N10|date=1 January 2022}}

• {{cite journal |last1=Hansel |first1=TT |last2=Johnston |first2=SL |last3=Openshaw |first3=PJ |year=2013 |title=Microbes and mucosal immune responses in asthma |doi=10.1016/S0140-6736(12)62202-8 |pmid=23428115 |journal=Lancet |volume=381 |issue=9869 |pages=861–873 |s2cid=24596808 |url=https://zenodo.org/record/3423604}}
• {{cite journal |last1=Chiu |first1=C |last2=Openshaw |first2=PJ |year=2015 |title=Antiviral B cell and T cell immunity in the lungs |journal=Nature Immunology |volume=16 |issue=1 |pages=18–26 |doi=10.1038/ni.3056 |pmid=25521681 |pmc=7097128}}
• {{Cite journal |last1=Habibi |first1=Maximillian S. |last2=Thwaites |first2=Ryan S. |last3=Openshaw |first3=Peter |last4=Jozwik |first4=Agnieszka |last5=Paras |first5=Allan |last6=Kirsebom |first6=Freja |last7=Varese |first7=Augusto |last8=Owen |first8=Amber |last9=Cuthbertson |first9=Leah |last10=James |first10=Phillip |last11=Tunstall |first11=Tanushree |last12=Nickle |first12=David |last13=Hansel |first13=Trevor T. |last14=Moffatt |first14=Miriam F. |last15=Johansson |first15=Cecilia |display-authors=3 |date=2020-10-09 |title=Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection |journal=Science |language=en |volume=370 |issue=6513 |doi=10.1126/science.aba9301 |issn=0036-8075 |pmc=7613218 |pmid=33033192}}
• {{Cite journal |last1=Thwaites |first1=Ryan S |last2=Sanchez Sevilla Uruchurtu |first2=Ashley |last3=Openshaw |first3=Peter |last4=Liew |first4=Felicity |last5=Russell |first5=Clark D |last6=Moore |first6=Shona C |last7=Fairfield |first7=Cameron |last8=Carter |first8=Edwin |last9=Abrams |first9=Simon |last10=Short |first10=Charlotte-Eve |last11=Thaventhiran |first11=Thilipan |last12=Bergstrom |first12=Emma |last13=Gardener |first13=Zoe |last14=Ascough |first14=Stephanie |last15=Chiu |first15=Christopher |display-authors=3 |date=2021-03-04 |title=Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19 |journal=Science Immunology |language=en |volume=6 |issue=57 |doi=10.1126/sciimmunol.abg9873 |pmid=33692097 |pmc=8128298 |issn=2470-9468}}
• {{Cite journal |last=Openshaw |first=Peter J. M. |date=2022-01-07 |title=Using correlates to accelerate vaccinology |url=https://www.science.org/doi/10.1126/science.abn0007 |journal=Science |language=en |volume=375 |issue=6576 |pages=22–23 |doi=10.1126/science.abn0007 |pmid=34990231 |bibcode=2022Sci...375...22O |issn=0036-8075}}
• {{Cite journal |last1=Pairo-Castineira |first1=Erola |last2=Rawlik |first2=Konrad |last3=Openshaw |first3=Peter |last4=Qi |first4=Ting |last5=Wu |first5=Yang |last6=Nassiri |first6=Isar |last7=McConkey |first7=Glenn A. |last8=Zechner |first8=Marie |last9=Klaric |first9=Lucija |last10=Griffiths |first10=Fiona |last11=Oosthuyzen |first11=Wilna |last12=Kousathanas |first12=Athanasios |last13=Richmond |first13=Anne |last14=Millar |first14=Jonathan |last15=Russell |first15=Clark D. |display-authors=3 |date=2023-05-25 |title=GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19 |journal=Nature |language=en |volume=617 |issue=7962 |pages=764–768 |doi=10.1038/s41586-023-06034-3 |issn=0028-0836 |pmc=10208981 |pmid=37198478}}
• {{Cite journal |last1=Thwaites |first1=Ryan S. |last2=Uruchurtu |first2=Ashley S. S. |last3=Openshaw |first3=Peter |last4=Cole |first4=Megan E. |last5=Singh |first5=Nehmat |last6=Poshai |first6=Nelisa |last7=Jackson |first7=David |last8=Hoschler |first8=Katja |last9=Baker |first9=Tina |last10=Scott |first10=Ian C. |last11=Ros |first11=Xavier Romero |last12=Cohen |first12=Emma Suzanne |last13=Zambon |first13=Maria |last14=Pollock |first14=Katrina M. |last15=Hansel |first15=Trevor T. |display-authors=3 |date=2023-12-05 |title=Early mucosal events promote distinct mucosal and systemic antibody responses to live attenuated influenza vaccine |journal=Nature Communications |language=en |volume=14 |issue=1 |page=8053 |doi=10.1038/s41467-023-43842-7 |issn=2041-1723 |pmc=10697962 |pmid=38052824|bibcode=2023NatCo..14.8053T }}
• {{Cite journal |last1=Sidhu |first1=Jasmin K |last2=Siggins |first2=Matthew K |last3=Openshaw |first3=Peter J M |last4=Russell |first4=Clark D |last5=Uruchurtu |first5=Ashley S S |last6=Davis |first6=Christopher |last7=Turtle |first7=Lance |last8=Moore |first8=Shona C |last9=Hardwick |first9=Hayley E |last10=Oosthuyzen |first10=Wilna |last11=Thomson |first11=Emma C |last12=Semple |first12=Malcolm G |last13=Baillie |first13=J Kenneth |last14=Thwaites |first14=Ryan S |display-authors=3 |date=2023-12-22 |title=Delayed Mucosal Antiviral Responses Despite Robust Peripheral Inflammation in Fatal COVID-19 |url=https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad590/7491611 |journal=The Journal of Infectious Diseases |language=en |doi=10.1093/infdis/jiad590 |pmid=38134401 |issn=0022-1899|hdl=20.500.11820/bed8141e-e4f2-482e-beae-1d084fe9ae37 |hdl-access=free }}
• {{Cite journal |last1=Wagstaffe |first1=Helen R. |last2=Thwaites |first2=Ryan S. |last3=Openshaw |first3=Peter |last4=Sidhu |first4=Jasmin K. |last5=McKendry |first5=Richard |last6=Ascough |first6=Stephanie |last7=Papargyris |first7=Loukas |last8=Collins |first8=Ashley M. |last9=Xu |first9=Jiayun |last10=Lemm |first10=Nana-Marie |last11=Siggins |first11=Matthew K. |last12=Chain |first12=Benny M. |last13=Killingley |first13=Ben |last14=Kalinova |first14=Mariya |last15=Mann |first15=Alex |display-authors=3 |date=2024-09-02 |title=Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adults |url=https://www.science.org/doi/10.1126/sciimmunol.adj9285 |journal=Science Immunology |language=en |volume=9 |issue=92 |pages=eadj9285 |doi=10.1126/sciimmunol.adj9285 |pmid=38335268 |issn=2470-9468}}

Openshaw has a son named Nick.{{cite web |last1=Taysom |first1=Joe |title=Florence Welch Talks About Alcohol and Her Grandmother's Suicide |url=https://faroutmagazine.co.uk/florence-welch-talks-about-her-battle-with-alcohol-and-grandmothers-suicide/ |website=Far Out Magazine |date=25 June 2018 |access-date=19 November 2018}} As well as two step daughters Florence Welch and Grace, and a step-granddaughter.{{Cite web |last=Huelsbeck |first=Mia |date=2023-12-11 |title=Tragic Details About Florence Welch |url=https://www.thelist.com/1465719/tragic-details-florence-welch/ |access-date=2024-07-30 |website=The List |language=en-US}}

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Category:1954 births

Category:Living people

Category:People educated at Millfield

Category:People educated at Sidcot School

Category:People educated at Bootham School

Category:British immunologists

Category:Alumni of King's College London

Category:Fellows of the Royal College of Physicians

Category:Fellows of the Academy of Medical Sciences (United Kingdom)

Category:NIHR Senior Investigators

Category:Commanders of the Order of the British Empire

Category:People from Glastonbury

Category:20th-century English medical doctors

Category:21st-century English medical doctors