RCAN2
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
RCAN2 is a gene that in humans encodes for the protein Calcipressin-2.
Calcipressin-2 is a protein that in humans is encoded by the RCAN2 gene.{{cite journal | vauthors = Miyazaki T, Kanou Y, Murata Y, Ohmori S, Niwa T, Maeda K, Yamamura H, Seo H | title = Molecular cloning of a novel thyroid hormone-responsive gene, ZAKI-4, in human skin fibroblasts | journal = J Biol Chem | volume = 271 | issue = 24 | pages = 14567–71 |date=Aug 1996 | pmid = 8662924 | doi =10.1074/jbc.271.24.14567 | doi-access = free }}{{cite web | title = Entrez Gene: DSCR1L1 Down syndrome critical region gene 1-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10231}}
Summary box
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See also
References
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Further reading
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- {{cite journal | vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 |doi-access=free }}
- {{cite journal |vauthors=Rothermel B, Vega RB, Yang J, etal |title=A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling. |journal=J. Biol. Chem. |volume=275 |issue= 12 |pages= 8719–25 |year= 2000 |pmid= 10722714 |doi=10.1074/jbc.275.12.8719 |doi-access=free }}
- {{cite journal |vauthors=Strippoli P, Lenzi L, Petrini M, etal |title=A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2). |journal=Genomics |volume=64 |issue= 3 |pages= 252–63 |year= 2000 |pmid= 10756093 |doi= 10.1006/geno.2000.6127 }}
- {{cite journal |vauthors=Fuentes JJ, Genescà L, Kingsbury TJ, etal |title=DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways. |journal=Hum. Mol. Genet. |volume=9 |issue= 11 |pages= 1681–90 |year= 2000 |pmid= 10861295 |doi=10.1093/hmg/9.11.1681 |doi-access=free }}
- {{cite journal |vauthors=Cao X, Kambe F, Miyazaki T, etal |title=Novel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitors |journal=Biochem. J. |volume=367 |issue= Pt 2 |pages= 459–66 |year= 2002 |pmid= 12102656 |doi= 10.1042/BJ20011797 | pmc=1222895 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
- {{cite journal |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
- {{cite journal |vauthors=Qin L, Zhao D, Liu X, etal |title=Down syndrome candidate region 1 isoform 1 mediates angiogenesis through the calcineurin-NFAT pathway |journal=Mol. Cancer Res. |volume=4 |issue= 11 |pages= 811–20 |year= 2007 |pmid= 17114339 |doi= 10.1158/1541-7786.MCR-06-0126 |doi-access= free }}
- {{cite journal | vauthors=Gollogly LK, Ryeom SW, Yoon SS |title=Down syndrome candidate region 1-like 1 (DSCR1-L1) mimics the inhibitory effects of DSCR1 on calcineurin signaling in endothelial cells and inhibits angiogenesis |journal=J. Surg. Res. |volume=142 |issue= 1 |pages= 129–36 |year= 2007 |pmid= 17610901 |doi= 10.1016/j.jss.2006.10.011 | pmc=1995402 }}
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External links
- {{UCSC genome browser|RCAN2}}
- {{UCSC gene details|RCAN2}}
{{gene-6-stub}}