RCC1

RCC1 has been shown to interact with RANBP3{{cite journal | vauthors = Nemergut ME, Lindsay ME, Brownawell AM, Macara IG | title = Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor | journal = The Journal of Biological Chemistry | volume = 277 | issue = 20 | pages = 17385–8 | date = May 2002 | pmid = 11932251 | doi = 10.1074/jbc.C100620200 | doi-access = free }}{{cite journal | vauthors = Mueller L, Cordes VC, Bischoff FR, Ponstingl H | title = Human RanBP3, a group of nuclear RanGTP binding proteins | journal = FEBS Letters | volume = 427 | issue = 3 | pages = 330–6 | date = May 1998 | pmid = 9637251 | doi = 10.1016/S0014-5793(98)00459-1 | doi-access = free }} and Ran (biology).{{cite journal | vauthors = Steggerda SM, Paschal BM | title = The mammalian Mog1 protein is a guanine nucleotide release factor for Ran | journal = The Journal of Biological Chemistry | volume = 275 | issue = 30 | pages = 23175–80 | date = July 2000 | pmid = 10811801 | doi = 10.1074/jbc.C000252200 | doi-access = free }}{{cite journal | vauthors = Renault L, Kuhlmann J, Henkel A, Wittinghofer A | title = Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1) | journal = Cell | volume = 105 | issue = 2 | pages = 245–55 | date = April 2001 | pmid = 11336674 | doi = 10.1016/S0092-8674(01)00315-4 | s2cid = 12827419 | doi-access = free }}{{cite journal | vauthors = Azuma Y, Renault L, García-Ranea JA, Valencia A, Nishimoto T, Wittinghofer A | title = Model of the ran-RCC1 interaction using biochemical and docking experiments | journal = Journal of Molecular Biology | volume = 289 | issue = 4 | pages = 1119–30 | date = June 1999 | pmid = 10369786 | doi = 10.1006/jmbi.1999.2820 }}{{cite journal | vauthors = Ren M, Villamarin A, Shih A, Coutavas E, Moore MS, LoCurcio M, Clarke V, Oppenheim JD, D'Eustachio P, Rush MG | title = Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing | journal = Molecular and Cellular Biology | volume = 15 | issue = 4 | pages = 2117–24 | date = April 1995 | pmid = 7891706 | pmc = 230439 | doi = 10.1128/MCB.15.4.2117 }}

{{Reflist}}

{{Refbegin | 2}}

• {{cite journal | vauthors = Furuno N, Nakagawa K, Eguchi U, Ohtsubo M, Nishimoto T, Soeda E, Ohtubo M | title = Complete nucleotide sequence of the human RCC1 gene involved in coupling between DNA replication and mitosis | journal = Genomics | volume = 11 | issue = 2 | pages = 459–61 | date = October 1991 | pmid = 1769659 | doi = 10.1016/0888-7543(91)90156-9 }}
• {{cite journal | vauthors = Bischoff FR, Ponstingl H | title = Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1 | journal = Nature | volume = 354 | issue = 6348 | pages = 80–2 | date = November 1991 | pmid = 1944575 | doi = 10.1038/354080a0 | bibcode = 1991Natur.354...80B | s2cid = 4346596 }}
• {{cite journal | vauthors = Bischoff FR, Ponstingl H | title = Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 88 | issue = 23 | pages = 10830–4 | date = December 1991 | pmid = 1961752 | pmc = 53025 | doi = 10.1073/pnas.88.23.10830 | bibcode = 1991PNAS...8810830B | doi-access = free }}
• {{cite journal | vauthors = Bischoff FR, Maier G, Tilz G, Ponstingl H | title = A 47-kDa human nuclear protein recognized by antikinetochore autoimmune sera is homologous with the protein encoded by RCC1, a gene implicated in onset of chromosome condensation | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 87 | issue = 21 | pages = 8617–21 | date = November 1990 | pmid = 2236072 | pmc = 55008 | doi = 10.1073/pnas.87.21.8617 | bibcode = 1990PNAS...87.8617B | doi-access = free }}
• {{cite journal | vauthors = Ohtsubo M, Okazaki H, Nishimoto T | title = The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA | journal = The Journal of Cell Biology | volume = 109 | issue = 4 Pt 1 | pages = 1389–97 | date = October 1989 | pmid = 2677018 | pmc = 2115805 | doi = 10.1083/jcb.109.4.1389 }}
• {{cite journal | vauthors = Ohtsubo M, Kai R, Furuno N, Sekiguchi T, Sekiguchi M, Hayashida H, Kuma K, Miyata T, Fukushige S, Murotsu T | title = Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation | journal = Genes & Development | volume = 1 | issue = 6 | pages = 585–93 | date = August 1987 | pmid = 3678831 | doi = 10.1101/gad.1.6.585 | doi-access = free }}
• {{cite journal | vauthors = Hayashi N, Yokoyama N, Seki T, Azuma Y, Ohba T, Nishimoto T | title = RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4 | journal = Molecular & General Genetics | volume = 247 | issue = 6 | pages = 661–9 | date = June 1995 | pmid = 7616957 | doi = 10.1007/BF00290397 | s2cid = 24266692 }}
• {{cite journal | vauthors = Nishimoto T, Seino H, Seki N, Hori TA | title = The human CHC1 gene encoding RCC1 (regulator of chromosome condensation) (CHC1) is localized to human chromosome 1p36.1 | journal = Genomics | volume = 23 | issue = 3 | pages = 719–21 | date = October 1994 | pmid = 7851910 | doi = 10.1006/geno.1994.1570 }}
• {{cite journal | vauthors = Miyabashira J, Sekiguchi T, Nishimoto T | title = Mammalian cells have two functional RCC1 proteins produced by alternative splicing | journal = Journal of Cell Science | volume = 107 ( Pt 8) | issue = 8 | pages = 2203–8 | date = August 1994 | doi = 10.1242/jcs.107.8.2203 | pmid = 7983178 }}
• {{cite journal | vauthors = Noguchi E, Hayashi N, Azuma Y, Seki T, Nakamura M, Nakashima N, Yanagida M, He X, Mueller U, Sazer S, Nishimoto T | title = Dis3, implicated in mitotic control, binds directly to Ran and enhances the GEF activity of RCC1 | journal = The EMBO Journal | volume = 15 | issue = 20 | pages = 5595–605 | date = October 1996 | pmid = 8896453 | pmc = 452304 | doi = 10.1002/j.1460-2075.1996.tb00944.x }}
• {{cite journal | vauthors = Renault L, Nassar N, Vetter I, Becker J, Klebe C, Roth M, Wittinghofer A | title = The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller | journal = Nature | volume = 392 | issue = 6671 | pages = 97–101 | date = March 1998 | pmid = 9510255 | doi = 10.1038/32204 | bibcode = 1998Natur.392...97R | s2cid = 4344559 }}
• {{cite journal | vauthors = Renault L, Nassar N, Wittinghofer A, Roth M, Vetter IR | title = Crystallization and preliminary X-ray analysis of human RCC1, the regulator of chromosome condensation | journal = Acta Crystallographica. Section D, Biological Crystallography | volume = 55 | issue = Pt 1 | pages = 272–5 | date = January 1999 | pmid = 10089422 | doi = 10.1107/S0907444998007768 | bibcode = 1999AcCrD..55..272R }}
• {{cite journal | vauthors = Azuma Y, Renault L, García-Ranea JA, Valencia A, Nishimoto T, Wittinghofer A | title = Model of the ran-RCC1 interaction using biochemical and docking experiments | journal = Journal of Molecular Biology | volume = 289 | issue = 4 | pages = 1119–30 | date = June 1999 | pmid = 10369786 | doi = 10.1006/jmbi.1999.2820 }}
• {{cite journal | vauthors = Talcott B, Moore MS | title = The nuclear import of RCC1 requires a specific nuclear localization sequence receptor, karyopherin alpha3/Qip | journal = The Journal of Biological Chemistry | volume = 275 | issue = 14 | pages = 10099–104 | date = April 2000 | pmid = 10744690 | doi = 10.1074/jbc.275.14.10099 | doi-access = free }}
• {{cite journal | vauthors = Nemergut ME, Macara IG | title = Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms | journal = The Journal of Cell Biology | volume = 149 | issue = 4 | pages = 835–50 | date = May 2000 | pmid = 10811825 | pmc = 2174574 | doi = 10.1083/jcb.149.4.835 }}
• {{cite journal | vauthors = Fontoura BM, Blobel G, Yaseen NR | title = The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import | journal = The Journal of Biological Chemistry | volume = 275 | issue = 40 | pages = 31289–96 | date = October 2000 | pmid = 10875935 | doi = 10.1074/jbc.M004651200 | doi-access = free }}
• {{cite journal | vauthors = Freire J, Covelo G, Sarandeses C, Díaz-Jullien C, Freire M | title = Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin alpha | journal = Biochemistry and Cell Biology | volume = 79 | issue = 2 | pages = 123–31 | year = 2001 | pmid = 11310559 | doi = 10.1139/bcb-79-2-123 }}
• {{cite journal | vauthors = Renault L, Kuhlmann J, Henkel A, Wittinghofer A | title = Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1) | journal = Cell | volume = 105 | issue = 2 | pages = 245–55 | date = April 2001 | pmid = 11336674 | doi = 10.1016/S0092-8674(01)00315-4 | s2cid = 12827419 | doi-access = free }}
• {{cite journal | vauthors = Nemergut ME, Mizzen CA, Stukenberg T, Allis CD, Macara IG | title = Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B | journal = Science | volume = 292 | issue = 5521 | pages = 1540–3 | date = May 2001 | pmid = 11375490 | doi = 10.1126/science.292.5521.1540 | bibcode = 2001Sci...292.1540N }}
• {{cite journal | vauthors = Nemergut ME, Lindsay ME, Brownawell AM, Macara IG | title = Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor | journal = The Journal of Biological Chemistry | volume = 277 | issue = 20 | pages = 17385–8 | date = May 2002 | pmid = 11932251 | doi = 10.1074/jbc.C100620200 | doi-access = free }}

{{Refend}}

{{PDB Gallery|geneid=1104}}

{{Protein-stub}}