RRAGA

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Ras-related GTP-binding protein A is a protein that in humans is encoded by the RRAGA gene.{{cite journal | vauthors = Schürmann A, Brauers A, Massmann S, Becker W, Joost HG | title = Cloning of a novel family of mammalian GTP-binding proteins (raga d, RagBs, RagB1) with remote similarity to the Ras-related GTPases | journal = The Journal of Biological Chemistry | volume = 270 | issue = 48 | pages = 28982–8 | date = Dec 1995 | pmid = 7499430 | doi = 10.1074/jbc.270.48.28982 | doi-access = free }}{{cite journal | vauthors = Li Y, Kang J, Horwitz MS | title = Interaction of an adenovirus 14.7-kilodalton protein inhibitor of tumor necrosis factor alpha cytolysis with a new member of the GTPase superfamily of signal transducers | journal = Journal of Virology | volume = 71 | issue = 2 | pages = 1576–82 | date = Feb 1997 | pmid = 8995684 | pmc = 191215 | doi = 10.1128/JVI.71.2.1576-1582.1997}}{{cite web | title = Entrez Gene: RRAGA Ras-related GTP binding A| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10670}}

Interactions

RRAGA has been shown to interact with NOL8{{cite journal | vauthors = Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T | title = A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D | journal = The Journal of Biological Chemistry | volume = 279 | issue = 9 | pages = 8343–50 | date = Feb 2004 | pmid = 14660641 | doi = 10.1074/jbc.M305935200 | doi-access = free }} and RRAGC.{{cite journal|author-link30=Huda Zoghbi | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R | s2cid = 4427026 }}{{cite journal | vauthors = Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T | title = Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B | journal = The Journal of Biological Chemistry | volume = 276 | issue = 10 | pages = 7246–57 | date = Mar 2001 | pmid = 11073942 | doi = 10.1074/jbc.M004389200 | doi-access = free }}

References

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Further reading

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  • {{cite journal | vauthors = Hirose E, Nakashima N, Sekiguchi T, Nishimoto T | title = RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway | journal = Journal of Cell Science | volume = 111 ( Pt 1) | issue = 1 | pages = 11–21 | date = Jan 1998 | doi = 10.1242/jcs.111.1.11 | pmid = 9394008 }}
  • {{cite journal | vauthors = Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T | title = Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B | journal = The Journal of Biological Chemistry | volume = 276 | issue = 10 | pages = 7246–57 | date = Mar 2001 | pmid = 11073942 | doi = 10.1074/jbc.M004389200 | doi-access = free }}
  • {{cite journal | vauthors = Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T | title = A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D | journal = The Journal of Biological Chemistry | volume = 279 | issue = 9 | pages = 8343–50 | date = Feb 2004 | pmid = 14660641 | doi = 10.1074/jbc.M305935200 | doi-access = free }}
  • {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R | s2cid = 4427026 }}

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{{Gene-9-stub}}