RRAGC
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Ras-related GTP binding C, also known as RRAGC, is a protein which in humans is encoded by the RRAGC gene.{{cite web | title = Entrez Gene: RRAGC Ras-related GTP binding C| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64121}}{{cite journal | vauthors = Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T | title = Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B | journal = The Journal of Biological Chemistry | volume = 276 | issue = 10 | pages = 7246–57 | date = Mar 2001 | pmid = 11073942 | doi = 10.1074/jbc.M004389200 | doi-access = free }}
RRAGC is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.
Interactions
RRAGC has been shown to interact with RRAGA.{{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M |authorlink30=Huda Zoghbi| title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 |bibcode=2005Natur.437.1173R|s2cid=4427026}}
References
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Further reading
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- {{cite journal | vauthors = Horwitz MS | title = Adenovirus immunoregulatory genes and their cellular targets | journal = Virology | volume = 279 | issue = 1 | pages = 1–8 | date = Jan 2001 | pmid = 11145883 | doi = 10.1006/viro.2000.0738 | doi-access = free }}
- {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R | s2cid = 4427026 }}
- {{cite journal | vauthors = Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T | title = A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D | journal = The Journal of Biological Chemistry | volume = 279 | issue = 9 | pages = 8343–50 | date = Feb 2004 | pmid = 14660641 | doi = 10.1074/jbc.M305935200 | doi-access = free }}
- {{cite journal | vauthors = Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T | title = Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B | journal = The Journal of Biological Chemistry | volume = 276 | issue = 10 | pages = 7246–57 | date = Mar 2001 | pmid = 11073942 | doi = 10.1074/jbc.M004389200 | doi-access = free }}
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