Ravi Salgia
{{short description|Indian-born American medical scientist}}
{{Use dmy dates|date=April 2023}}
{{Use Indian English|date=April 2023}}
{{Infobox scientist
| name = Ravi Salgia
| native_name =
| native_name_lang =
| image =
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| birth_date = {{birth year and age|1960}}
| birth_place = Indore, India
| citizenship = American
| nationality =
| fields = Oncology
| workplaces = {{plainlist|
- Johns Hopkins University
- Harvard Medical School
- Dana–Farber Cancer Institute
- Brigham and Women's Hospital
- University of Chicago
- City of Hope National Medical Center
}}
| education =
| alma_mater = Loyola University of Chicago
| known_for =
| awards =
| spouse = Deborah Ann Salgia
| children = 3
| website =
}}
Ravi Salgia (born 1960) is a translational thoracic oncologist, clinician/scientist, and academician.{{cite web|url=https://www.ascopost.com/issues/january-25-2016/ravi-salgia-md-phd-joins-city-of-hope/|title=Ravi Salgia, MD, PhD, Joins City of Hope|last=|first=|date=|website=|publisher=ascopost.com|accessdate=2019-09-08}}
Biography and career
Salgia is the Arthur & Rosalie Kaplan Endowed Chair of Medical Oncology at City of Hope National Medical Center in Duarte, California. He also serves as Associate Director for Clinical Sciences at City of Hope National Medical Center. Prior to joining City of Hope, he served as tenured Professor of Medicine, Pathology and Dermatology, Director of the Thoracic Oncology Program and the Aerodigestive Tract Program Translational Research Lab in the section of Hematology/Oncology, Vice Chair for Translational Research in the Department of Medicine and Associate Director for Translational Science at the University of Chicago Comprehensive Cancer Center in Chicago.{{Cite web|url=https://www.cityofhope.org/news/acclaimed-oncologist-researcher-ravi-salgia-joins-city-of-hope|title=Acclaimed oncologist/researcher Ravi Salgia joins City of Hope as chair of medical oncology|website=www.cityofhope.org|access-date=2019-09-09}}
During his fellowship in Professor James Griffin's laboratory at Harvard, Salgia worked on the cytoskeleton, signal transduction pathways and hematpoiesis/Chronic myelogenous leukemia.{{Cite journal|last1=Salgia|first1=R.|last2=Avraham|first2=S.|last3=Pisick|first3=E.|last4=Li|first4=J. L.|last5=Raja|first5=S.|last6=Greenfield|first6=E. A.|last7=Sattler|first7=M.|last8=Avraham|first8=H.|last9=Griffin|first9=J. D.|date=1996-12-06|title=The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells|journal=The Journal of Biological Chemistry|volume=271|issue=49|pages=31222–31226|doi=10.1074/jbc.271.49.31222|issn=0021-9258|pmid=8940124|doi-access=free}}{{Cite journal|last1=Salgia|first1=R.|last2=Pisick|first2=E.|last3=Sattler|first3=M.|last4=Li|first4=J. L.|last5=Uemura|first5=N.|last6=Wong|first6=W. K.|last7=Burky|first7=S. A.|last8=Hirai|first8=H.|last9=Chen|first9=L. B.|date=1996-10-11|title=p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene|journal=The Journal of Biological Chemistry|volume=271|issue=41|pages=25198–25203|doi=10.1074/jbc.271.41.25198|issn=0021-9258|pmid=8810278|doi-access=free}}{{Cite journal|last1=Salgia|first1=R.|last2=Sattler|first2=M.|last3=Pisick|first3=E.|last4=Li|first4=J. L.|last5=Griffin|first5=J. D.|date=February 1996|title=p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl|journal=Experimental Hematology|volume=24|issue=2|pages=310–313|issn=0301-472X|pmid=8641358}}{{Cite journal|last1=Okuda|first1=K.|last2=Matulonis|first2=U.|last3=Salgia|first3=R.|last4=Kanakura|first4=Y.|last5=Druker|first5=B.|last6=Griffin|first6=J. D.|date=October 1994|title=Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1|journal=Experimental Hematology|volume=22|issue=11|pages=1111–1117|issn=0301-472X|pmid=7925778}} He was the first to fully clone the focal adhesion protein paxillin (human and chicken) and demonstrate its role in oncogenic transformation.{{Cite journal|last1=Salgia|first1=R.|last2=Li|first2=J. L.|last3=Lo|first3=S. H.|last4=Brunkhorst|first4=B.|last5=Kansas|first5=G. S.|last6=Sobhany|first6=E. S.|last7=Sun|first7=Y.|last8=Pisick|first8=E.|last9=Hallek|first9=M.|date=1995-03-10|title=Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL|journal=The Journal of Biological Chemistry|volume=270|issue=10|pages=5039–5047|doi=10.1074/jbc.270.10.5039|issn=0021-9258|pmid=7534286|doi-access=free}} As an independent clinician-scientist, Salgia's major research interests include elucidating how the receptor tyrosine kinases affect cell growth, and understanding tumor heterogeneity, including the role of cell-signaling pathways, mitochondria, immunology, and mathematical modeling{{Cite web|url=https://pubmed.ncbi.nlm.nih.gov/?term=ravi+Salgia|title=ravi Salgia - PubMed - NCBI|last=pubmeddev|website=www.ncbi.nlm.nih.gov|access-date=2019-09-09}}
Salgia was born in Indore, Madhya Pradesh, India. He earned his undergraduate degree summa cum laude in mathematics, biology, and chemistry, minor in physics and then his medical degree and Ph.D. in biochemistry and biophysics from Loyola University of Chicago.{{Cite web|url=https://www.cityofhope.org/people/salgia-ravi|title=Ravi Salgia, M.D., Ph.D., Chair and Professor of City of Hope's Department of Medical Oncology & Therapeutics Research|website=www.cityofhope.org|access-date=2019-09-09}} There he also completed a fellowship in neurochemistry and physiology. He continued his postgraduate training with an internship and residency in internal medicine at the Johns Hopkins Hospital in Baltimore, followed by a fellowship in medical oncology at Dana–Farber Cancer Institute in Boston, during which time he also served as a clinical fellow at Harvard Medical School in Boston.{{Cite web|url=https://www.businesswire.com/news/home/20160113005271/en/Acclaimed-OncologistResearcher-Ravi-Salgia-Joins-City-Hope|title=Acclaimed Oncologist/Researcher Ravi Salgia Joins City of Hope as Chair of Medical Oncology|date=2016-01-13|website=www.businesswire.com|access-date=2019-09-09}}
Salgia has been married to Deborah A. Salgia since 1990 and they have three children.{{fact|date=April 2023}}
References
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Category:Loyola University Chicago alumni
Category:University of Chicago faculty