Ruscus
{{Short description|Genus of flowering plants}}
{{Expand Polish|Myszopłoch|date=May 2022}}
{{Automatic taxobox
|taxon = Ruscus
|image = Ruscus aculeatus0.jpg
|image_caption = Ruscus aculeatus
|authority = L.
|synonyms_ref=[http://apps.kew.org/wcsp/namedetail.do?name_id=286744 Kew World Checklist of Selected Plant Families]
|synonyms=*Hippoglossum Hill
- Oxymyrsine Bubani
- Platyruscus A.P.Khokhr. & V.N.Tikhom.
}}
Ruscus, commonly known as butcher's broom, is a genus of six species of flowering plants, native to western and southern Europe, Macaronesia, northwestern Africa, and southwestern Asia east to the Caucasus. In the APG III classification system, it is placed in the family Asparagaceae, subfamily Nolinoideae (formerly the family Ruscaceae).{{Citation |last1=Chase |first1=M.W. |last2=Reveal |first2=J.L. |last3=Fay |first3=M.F. |year=2009 |title=A subfamilial classification for the expanded asparagalean families Amaryllidaceae, Asparagaceae and Xanthorrhoeaceae |journal=Botanical Journal of the Linnean Society |volume=161 |issue=2 |pages=132–136 |doi=10.1111/j.1095-8339.2009.00999.x|name-list-style=amp |doi-access=free }} Like many lilioid monocots, it was formerly classified in the family Liliaceae.
The species are evergreen shrub-like perennial plants, growing to approximately {{convert|1|m}} tall. They have branched stems that bear numerous cladodes (flattened, leaf-like stem tissue, also known as phylloclades) {{convert|2|to|18|cm}} long and {{convert|1|to|8|cm}} broad. The true leaves are minute, scale-like, and non-photosynthetic. The flowers are small, white with a dark-violet centre, and situated on the middle of the cladodes. The fruit is a red berry {{convert|5|to|10|mm}} in diameter. Some species are monoecious while others are dioecious.
Ruscus is spread by seed and by means of underground rhizomes. It can colonise extensive patches of ground.
Image:Ruscus aculeatus bugelenn liliacea (fragon).JPG habit]]
Image:Ruscus hypoglossum at The Grand Canyon Of Crimea.jpg]]
Species
- Ruscus aculeatus (butcher's broom). Europe, Azores.
- Ruscus colchicus Caucasus.
- Ruscus hypoglossum Central and Southeast Europe, Turkey.
- Ruscus hypophyllum (spineless butcher's broom). Iberia, northwest Africa. Used in the floral trade as foliage.
- Ruscus hyrcanus Woronow An endemic and relict bush in the Talish Mountains, Azerbaijan. Protected in the Hirkan national Park.{{citation needed|date=April 2012}}
- Ruscus x microglossus Southern Europe.
- Ruscus streptophyllus Madeira.{{cite journal |author=P. F. Yeo |title=Two New Species of Ruscus (Liliaceae) |journal=Feddes Repertorium |volume=73 |issue=1 |pages=17–20 |year=1966 |doi=10.1002/fedr.19660730103}}
Uses
=[[Medicinal plants]]=
==History==
Various species of butcher's broom have been used for medicinal purposes since antiquity. The first mentions of the medicinal use of the butcher's broom come from ancient Greece. The rhizomes of this plant were used to treat inflammations, hemorrhoids, and urinary tract conditions, as well as a diuretic and laxative.{{cite web|access-date=2021-09-24|author=Matej Barbic|title=Isolation and identification of the constituents from Ruscus aculeatus L. and their in vitro activity|url=https://core.ac.uk/reader/11548567}} In the 1st century De Materia Medica by Dioscorides, the plants described are: ύπόγλοσσον (ypoglosson), probably Ruscus hypoglossum, ιδαια ριζα (idaia riza), also probably R. hypoglossum{{cite book|date=2017|edition=3|first=Pedanios|isbn=9783487155715|last=Dioskurydes|others=Lily Y. Beck (tłum.)|title=De materia medica|publisher=Georg Olms Verlag}} and μυρσίνη άγρία (myrsini agria), probably R. aculeatus.{{cite book|date=2005|edition=1|first=Pedanios|isbn=3487128810|last=Dioskurydes|others=Lily Y. Beck (tłum.)|title=De materia medica|publisher=Olms-Weidmann}} Dioscorides indicated the laxative and diuretic effects of these plants.{{cite book|date=2013|edition=2|first1=Kerry|first2=Simon|isbn=9780702052972|last1=Bone|last2=Mills|location=Edinburgh|page=467-472|publisher=Elsevier Health Sciences|title=Principles and practice of phytotherapy: modern herbal medicine}} Pliny the Elder in his Natural History pointed out the use of these plants in treating varicose veins.{{cite book|date=2011|first=Bashar|isbn=9781118002261|last=Saad|location=Hoboken, N.J.|publisher=Wiley|title=Greco-Arab and Islamic Herbal Medicine : Traditional System, Ethics, Safety, Efficacy, and Regulatory Issues}} In the Herbal of Simon Syreński, first published in 1613, the butcher's broom is described as a plant with healing power, for use in urinary retention, kidney stones, and accelerating menstruation, mainly in the form of a wine tincture.{{cite book|author-link=Szymon Syreński (Syreniusz)|date=1613|first=Szymon|last=Syreński|location=Kraków|title=Zielnik}} Also, in the 17th-century work Janua linguarum reserata by Comenius, the butcher's broom was described as a warm herb for kidney diseases.{{cite book|author-link=Jan Ámos Komenský|date=1768|first=Jan Ámos|last=Komenský|location=Wilno|publisher=Scholarium Piarum|title=Janua aurea reserata duarum linguarum}} In the 1852 work Special Botany: Description of Monocotyledonous Medicinal and Industrial Plants by Ignacy Czerwiakowski, the author reported that the root of butcher's broom (radix Rusci v. Brusci) was formerly used as "an opening and diuretic agent in dropsy and blockages of the viscera", part of the herbal mixture radices quinque aperientes majores (five major opening roots), and also used in treating jaundice and kidney stones, and to accelerate menstruation. The author also mentioned that the root of R. hypophyllum had medical applications, including in difficult births, retention of menstruation, and urinary system conditions. In the case of R. hypoglossum, Czerwiakowski mentioned the use of this plant's herb for throat and uterine conditions.{{cite book|author=Ignacy Rafał Czerwiakowski|date=1852|language=pl|location=Kraków|page=613-615|publisher=Uniwersytet Jagielloński|title=Botanika szczególna|volume=2 Opisanie roślin jednolistniowych lekarskich i przemysłowych}}
==Indications==
Butcher's broom is used in traditional medicine in many countries around the Mediterranean Sea. In Europe, the underground parts are traditionally used in the treatment of urinary system conditions and as a laxative, while the aboveground parts are mainly used as diuretics.{{cite journal|date=2021-03-26|doi=10.3390/molecules26071882|edition=7|first=Joana P. B.|journal=Molecules|last=Rodrigues|page=1882|title=Phenolic Compounds and Bioactive Properties of Ruscus aculeatus L. (Asparagaceae): The Pharmacological Potential of an Underexploited Subshrub|volume=26|issue=7 |doi-access=free|pmid=33810432 |pmc=8037534 |hdl=10198/24369|hdl-access=free}} In folk medicine in Turkey, a decoction of the roots of butcher's broom is widely used internally as a diuretic and for treating urinary system conditions, such as kidney inflammation and kidney stones, as well as for treating eczema. In Palestine, an extract from the rhizome is used externally for skin diseases, while in Italy it is used in treating warts and frostbite, with inflammatory bowel diseases and diarrhea, and topically in joint inflammation. The aboveground parts of the plant are traditionally used as diuretics, mainly in Mediterranean countries and the Middle East.{{cite journal|date=2016-11-08|doi=10.1055/s-0042-119728|edition=18|first1=Milena|first2=Cosimo|first3=Sonia|journal=Planta Medica|last1=Masullo|last2=Pizza|last3=Piacente|pages=1513–1524|title=Ruscus Genus: A Rich Source of Bioactive Steroidal Saponins|volume=82|issue=18 |doi-access=free|pmid=27825178 |bibcode=2016PlMed..82.1513M }}
In Turkey, a decoction of the berries of Ruscus hypoglossum is used externally for boils and warts, and fresh leaves are used in cattle breeding against colds and mastitis. The leaves of R. colchicus are used by the local population for feeding farm animals to increase milk production and fat content.
Ruscus hyrcanus is used in traditional Iranian medicine as a diuretic, hemostatic, vasoconstrictor, antimicrobial, and anti-inflammatory agent.
==Current Use==
Presently, butcher's broom is not widely used in modern medicine due to a lack of comprehensive clinical studies proving its effectiveness. However, extracts of this plant are found in some pharmaceutical and cosmetic products, such as creams for varicose veins and hemorrhoids. Preparations of the plant are also used in homeopathy.
Some recent studies have indicated that the plant may have potential pharmacological effects, such as anti-inflammatory, antimicrobial, and antioxidant activities. These studies suggest the possibility of its future application in modern medicine, especially in diseases related to inflammation and oxidative stress.
=Culinary=
In Italy the tender young, {{convert|5–20|cm|in}} long, pinkish-white shoots are consumed boiled like asparagus. As of 1997,Annex V of Directive 92/42/EEC and subsequent amendments (and related Annex E of Presidential Decree 357/1997 and subsequent amendments). it has been planned to introduce management measures to protect its overexploitation.{{sfn|Banfi|Colombo|Davanzo|Falciola|2012|p=126}}
=Toxicity=
The {{ill|Milan Poison Control Centre|it|Centro antiveleni di Milano}} handled 107 R. aculeatus poisoning cases in the period 1995–2007; subsequently 4 acute poisoning cases were recorded for the 2010–2011 season in Lombardy. The majority of cases were children who had consumed the attractive berries.{{sfn|Banfi|Colombo|Davanzo|Falciola|2012}}
{{sticky header}}
| class="wikitable sortable plainrowheaders sticky-header"" style="line-height:1.3em; max-width:1200px"
|+Common Ruscus toxins |
| rowspan="2" | Compound
! rowspan="2" | EINECS Number ! rowspan="2" | CAS Number ! rowspan="2" | GHS Class (Oral) ! rowspan="2" | Oral LD₅₀ (mg/kg) ! colspan="3" | R. aculeatus (%DW) ! colspan="3" | R. hypoglossum (%DW) ! rowspan="2" | Sources |
|---|
| Rhizome
! Aerial ! Fruit ! Rhizome ! Aerial ! Fruit |
| Neoruscogenin
| 241-660-1 | 17676-33-4 | H302 | 5000 | 0.173% | ? | ? | ? | ? | ? |
| Ruscogenin
| 207-447-2 | 472-11-7 | H302 | 8000 | 0.111% | 0.03-0.05% | ? | 0.14% | 0.10% | ? |
References
{{Reflist}}
Bibliography
- {{cite web |date=2025b |author=NCBI |author-link=National Center for Biotechnology Information |title=PubChem Compound Summary for CID 9910474, Neoruscogenin |url=https://pubchem.ncbi.nlm.nih.gov/compound/Neoruscogenin |website=PubChem |access-date=2025-06-06}}
- {{cite web |date=2025a |author=NCBI |author-link=National Center for Biotechnology Information |title=PubChem Compound Summary for CID 441893, Ruscogenin |url=https://pubchem.ncbi.nlm.nih.gov/compound/Ruscogenin |website=PubChem |access-date=2025-06-06}}
- {{cite journal |date=2025-03-17 |first1=Ovinuchi |last1=Ejiohuo |first2=Donald |last2=Bajia |first3=Joanna |last3=Pawlak |first4=Aleksandra |last4=Szczepankiewicz |title=In silico identification of novel ligands targeting stress-related human FKBP5 protein in mental disorders |doi=10.1371/journal.pone.0320017 |journal=PLOS ONE |volume=20 |issue=3 |pages=e0320017 |doi-access=free |bibcode=2025PLoSO..2020017E |eissn=1932-6203}}
- {{cite web |date=2025b |author=Chemicalbook |title=Ruscogenin Chemical Safety Data Sheet MSDS / SDS |url=https://www.chemicalbook.com/msds/ruscogenin.htm |website=ChemicalBook |access-date=2025-06-06}}
- {{cite web |date=2025a |author=Chemicalbook |title=Neoruscogenin Chemical Safety Data Sheet MSDS / SDS |url=https://www.chemicalbook.com/msds/neoruscogenin.htm |website=ChemicalBook |access-date=2025-06-06}}
- {{cite journal |date=2016 |first1=Milena |last1=Masullo |first2=Cosimo |last2=Pizza |first3=Sonia |last3=Piacente |title=Ruscus Genus: A Rich Source of Bioactive Steroidal Saponins |pages=1513–1524 |url=https://magistralbr.caldic.com/storage/product-files/779958021.pdf |journal=Planta Medica |eissn=1439-0221 |volume=82 |issue=18|doi=10.1055/s-0042-119728 |pmid=27825178 |bibcode=2016PlMed..82.1513M }}
- {{cite journal |date=2012 |first1=Enrico |last1=Banfi |first2=Maria Laura |last2=Colombo |first3=Franca |last3=Davanzo |first4=Chiara |last4=Falciola |first5=Gabriele |last5=Galasso |first6=Emanuela |last6=Martino |first7=Sandro |last7=Perego |title=Piante velenose della flora italiana nell'esperienza del Centro Antiveleni di Milano |url=http://scienzenaturali.org/wp-content/uploads/2018/02/Natura%20102-1%202012.pdf |journal=Natura: Rivista di Scienze Naturali |issn=0369-6243 |volume=102 |issue=1 |language=it |trans-title=Poisonous Plants of the Italian Flora in the Experience of the Milan Poison Control Centre}}
- {{cite journal |date=2009 |first1=Laurian |last1=Vlase |first2=Béla |last2=Kiss |first3=Georgeta |last3=Balica |first4=Mircea |last4=Tămas |first5=Gianina |last5=Crisan |first6=Sorin E. |last6=Leucuta |title=High-Throughput LC/MS/MS Analysis of Ruscogenin and Neoruscogenin in Ruscus aculeatus L |pages=1055–1059 |url=https://www.researchgate.net/publication/215738505 |doi=10.1093/jaoac/92.4.1055 |journal=Journal of AOAC International |eissn=1944-7922 |volume=92 |issue=4|pmid=19714971 }}
- {{cite journal |date=2007 |first1=Sezen |last1=Tansi |first2=G. |last2=Kokdil |first3=S. |last3=Karaman |first4=Ozlem |last4=Toncer |first5=H. |last5=Yilmaz |title=Variation in ruscogenin contents in Ruscus aculeatus L. growing wild in Southern Turkey |pages=3015–3022 |url=https://www.researchgate.net/publication/279605533 |journal=Asian Journal of Chemistry |eissn=0975-427X |volume=19 |issue=4}}
External links
- [http://rbg-web2.rbge.org.uk/cgi-bin/nph-readbtree.pl/feout?FAMILY_XREF=&GENUS_XREF=Ruscus&SPECIES_XREF=&TAXON_NAME_XREF=&RANK= Flora Europaea: Ruscus]
{{Taxonbar|from=Q157597}}
{{Authority control}}