STP

• São Tomé and Príncipe (ISO 3166-1 alpha-3 code, IOC country code, and FIFA country code STP)
• St Pancras railway station (National Rail code STP)
• St. Paul Downtown Airport (IATA airport code STP) in Saint Paul, Minnesota, US
• South Texas Nuclear Generating Station, also known as the South Texas Project

• German Union of Saddlers, Upholsterers and Portfolio Makers, a former German trade union
• STP (motor oil company)
• Segmenting-targeting-positioning, a framework in marketing
• Society for Threatened Peoples, an international NGO
• Space Test Program, a spaceflight provider for US DoD
• Straight-through processing, in securities transaction
• Suntech Power (NYSE symbol STP)

• 2,5-Dimethoxy-4-methylamphetamine, also called DOM or "serenity, tranquility, and peace"

• Star Trek: Picard (2020 TV series), an American science fiction TV series
• Star Trek: Prodigy (2021 TV series), an American science fiction children's TV series

• Stone Temple Pilots, an American rock band
• Slaughter to Prevail, a Russian deathcore band
• "S.T.P.", a song on the album Robbin' the Hood by the band Sublime
• STP, an American band with Julia Cafritz

• ISO 10303-21, the STEP CAD exchange file extension
• Serial ATA Tunneling Protocol, supporting SATA devices in SAS bays
• Server Time Protocol, to synchronize clocks
• Shielded twisted pair, a type of cable
• Signal Transfer Point, an SS7 packet switch
• Spanning Tree Protocol, a network protocol used for loop prevention
• Schedule Transfer Protocol, a network protocol designed for low-latency data transfer
• Software Technology Parks of India
• Straight-through processing, without repeating data entry for a financial transaction

• Scientist Training Programme, a UK healthcare training scheme under Modernising Scientific Careers
• Sustainability and transformation plan, a scheme in NHS England

• Standard temperature and pressure, 0 °C and 100 kPa
• Sewage Treatment Plant, a site where wastewater is cleaned
• Shovel test pit, a method of archaeological survey
• Sodium triphosphate, used in detergents, etc.
• Stand-to-pee device, a female urination device
• Solar Terrestrial Probes program, a series of NASA missions
• Silane-terminated polymers

• Sacrae Theologiae Professor, a Catholic degree
• Seattle to Portland Bicycle Classic
• Soviet-type economic planning
• 25 metre standard pistol, a shooting sport
• Sticky toffee pudding

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