Sagar Sengupta
{{Short description|Indian immunologist and cancer biologist}}
{{Use dmy dates|date=July 2018}}
{{Use Indian English|date=July 2018}}
{{Infobox scientist
| name = Sagar Sengupta
| image =
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| birth_place = West Bengal, India
| death_date =
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| nationality = Indian
| fields = {{ublist | Immunology | Oncology }}
| workplaces = {{ublist | National Institute of Immunology, India }}
{{ublist | National Institute of Biomedical Genomics, India }}
| alma_mater = {{ublist | University of Calcutta | Indian Institute of Science | IGBMC | National Institutes of Health }}
| doctoral_advisor =
| doctoral_students =
| known_for = Studies on tumor suppressor gene and oncogenes
| awards = {{ublist| 2011 N-BIOS Prize }}
}}
Sagar Sengupta is an Indian cancer biologist, a scientist at the National Institute of Immunology, India and Director, National Institute of Biomedical Genomics, Kalyani, India. Known for his studies on genome integrity, tumor suppressor gene and oncogenes, Sengupta is an elected fellow of all the three major Indian science academies namely the National Academy of Sciences, India, the Indian National Science Academy and the Indian Academy of Sciences. He has been a Jagadish Chandra Bose (JC Bose) Fellow since 2018. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2011.
Biography
Sagar Sengupta was born in the Indian state of West Bengal, earned a postgraduate degree from the University of Calcutta and secured a PhD from the Indian Institute of Science.{{Cite web |url=http://www.nii.res.in/research/sagar-sengupta |title=Sagar Sengupta on NII |date=2018-01-27 |website=www.nii.res.in |access-date=2018-01-27}} He did his post doctoral studies at the Institut de Genetique et de Biologie Moleculaire et Cellulaire (IGBMC) in Strasbourg, France and completed it at the National Cancer Institute of the National Institutes of Health.{{Cite web |url=http://www.incredb.org/investigator.php?incredb_id=415 |title=Sagar Sengupta, profile in India Cancer Research Database |date=2018-01-27 |website=www.incredb.org |access-date=2018-01-27}} Subsequently, he joined the National Institute of Immunology, India in 2004 as a faculty. He served in National Institute of Immunology till 2022 as a Grade VII Staff Scientist.{{Cite web |url=http://insaindia.res.in/detail/P17-1761 |title=Indian fellow |date=2018-01-25 |publisher=Indian National Science Academy |access-date=2018-01-25}} In November 2022, Sengupta became the Director of National Institute of Biomedical Genomics on deputation from National Institute of Immunology. The permanent residence of Sengupta is in Gurgaon, Haryana.{{Cite web |url=http://www.nasi.org.in/fellows.asp?RsFilter=S |title=NASI fellows |date=2018-01-25 |publisher=National Academy of Sciences, India |access-date=2018-01-25}}
Professional profile
Sengupta's research focus is on the changes in the signaling pathways during cancer development and he has carried out studies on the tumour suppressor genes and oncogenes. During his post-doctoral days at the National Institutes of Health (NIH), he undertook a project on NIH grant to study the Determination of regulatory mechanisms for BLM helicase.{{Cite journal |url=http://grantome.com/grant/NIH/R01-TW007302-04 |title=Determination of regulatory mechanisms for BLM helicase |last=Sagar |first=Sengupta |date=2018-01-27 |website=Grantome |language=en |access-date=2018-01-27}} His studies have been documented by way of a number of articles{{Cite web |url=https://scholar.google.com/citations?user=Bc4SKwgAAAAJ&hl=en |title=On Google Scholar |date=2018-01-20 |publisher=Google Scholar |access-date=2018-01-20}}{{Refn|group=note|Please see Selected bibliography section}} and ResearchGate, an online repository of scientific articles has listed over 50 of them.{{Cite web |url=https://www.researchgate.net/profile/Sagar_Sengupta |title=On ResearchGate |date=2018-01-20 |access-date=2018-01-20}} The complete list of his publications can be found at: https://www.ncbi.nlm.nih.gov/myncbi/1t7wpVLc8yt/bibliography/public/
He has also undertaken several projects on behalf of the government agencies such as the Department of Science and Technology, the Science and Engineering Research Board, the Department of Biotechnology and the Council of Scientific and Industrial Research and the Board of Research in Nuclear Sciences as the principal investigator and is associated with the Department of Biotechnology as a member of its Task force on Cancer Biology, the expert committee on Promotion and Popularization of Biotechnology and the Expert Committee for Twinning RD program for North Eastern Region.{{Cite web |url=http://www.ias.ac.in/MYM2017/Speakers/Sagar_Sengupta |title=Sagar Sengupta - Speakers - Indian Academy of Sciences |date=2018-01-27 |website=www.ias.ac.in |language=en |access-date=2018-01-27}}
Awards and honors
Sengupta received the Best Thesis Award for his doctoral thesis from the Indian Institute of Science in 1991. The Department of Biotechnology (DBT) of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards in 2011.{{Cite web |url=http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf |title=Awardees of National Bioscience Awards for Career Development |date=2016 |publisher=Department of Biotechnology |access-date=2017-11-20}} The National Academy of Sciences, India elected him as a fellow in 2012{{Cite web |url=http://www.nasi.org.in/Year%20Book%202015.pdf |title=NASI Year Book 2015 |date=2018-01-25 |publisher=National Academy of Sciences, India |access-date=2018-01-25}} and he became an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy in 2017.{{Cite web |url=http://www.ias.ac.in/listing/fellows/S |title=Fellowship - Indian Academy of Sciences |date=2018-01-27 |website=www.ias.ac.in |language=en |access-date=2018-01-27}} He is also a member of the Guha Research Conference.He has been a Jagadish Chandra Bose (JC Bose) Fellow since 2018.
Selected bibliography
= Articles =
- {{Cite journal |last1=Sengupta |first1=Sagar |last2=Harris |first2=Curtis C. |date=2005 |title=p53: traffic cop at the crossroads of DNA repair and recombination |journal=Nature Reviews Molecular Cell Biology |language=En |volume=6 |issue=1 |pages=44–55 |doi=10.1038/nrm1546 |pmid=15688066 |s2cid=11972657 |issn=1471-0080}}
- {{Cite journal |last1=Sengupta |first1=Sagar |last2=Robles |first2=Ana I. |last3=Linke |first3=Steven P. |last4=Sinogeeva |first4=Natasha I. |last5=Zhang |first5=Ran |last6=Pedeux |first6=Remy |last7=Ward |first7=Irene M. |last8=Celeste |first8=Arkady |last9=Nussenzweig |first9=André |date=2004-09-13 |title=Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest |journal=J Cell Biol |language=en |volume=166 |issue=6 |pages=801–813 |doi=10.1083/jcb.200405128 |issn=0021-9525 |pmid=15364958|pmc=2172115 }}
- {{Cite journal |last1=Sengupta |first1=Sagar |last2=Wasylyk |first2=Bohdan |date=2001-09-15 |title=Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2 |journal=Genes & Development |language=en |volume=15 |issue=18 |pages=2367–2380 |doi=10.1101/gad.202201 |issn=0890-9369 |pmid=11562347|pmc=312780 }}
See also
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{{portal|India|Biology|Medicine}}
Notes
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References
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External links
- {{Cite web |url=https://www.youtube.com/watch?v=xm8A07H45V0 |title=Mechanisms that Prevent Carcinogenesis: Study of a Family of Caretaker Tumour Suppressors |last=Sagar Sengupta |date=21 July 2017 |publisher=Indian Academy of Sciences |format=YouTube video |access-date=2018-01-27}}
{{N-BIOS Laureates 2010–2019}}
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Category:N-BIOS Prize recipients
Category:20th-century Indian biologists
Category:Indian medical researchers
Category:Fellows of the National Academy of Sciences, India
Category:Scientists from West Bengal
Category:University of Calcutta alumni
Category:Indian Institute of Science alumni
Category:National Institutes of Health people